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NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)

Up to $1,050,000
Type
GRANTS AND FUNDING
Application Difficulty
MEDIUM
Application DeadlineNovember 13, 2026
Time To Complete4 weeksProgram Budgetno cap
See If You Qualify

Highlights

This program is a perfect fit for your business if you're looking to advance your research on natural products like botanicals or dietary supplements. By applying, you can secure up to three years of funding to conduct vital early phase clinical trials. This funding will help you explore the effects of these natural products on human health, contributing valuable insights that could guide further research and development. You'll have the chance to test various formulations and dosages, optimizing results and even potentially combining them with other treatments.

Joining this initiative positions you at the forefront of innovation, allowing you to play a vital role in shaping the future of healthcare. Not only will your work contribute to advancements in natural health products, but it also opens doors for future funding opportunities based on the meaningful data you gather. With no minimum revenue or employee requirements, the pathway to approval is streamlined, making it accessible for businesses like yours to take part in something impactful and transformative.

Financing Details

Type of Financing

This program offers grant funding for early-phase clinical trials focused on natural products. Grants do not need to be repaid, making them an attractive option for your business.

Repayment Terms and Interest Rates

Since it's a grant, there are no repayment terms or interest rates involved. You can use the funds to support your project without worrying about paying it back later.

Eligible Expenses

You can use the funds for a variety of expenses related to your clinical trials, including:

  • Personnel costs (salaries for researchers and staff)
  • Supplies needed for conducting trials
  • Equipment purchases or rentals
  • Travel expenses for research activities
  • Services from external experts or institutions

Ineligible Expenses

Keep in mind that the funding cannot be used for:

  • Efficacy or effectiveness trials
  • General operating expenses unrelated to the project

Fees Associated with the Program

There are no fees associated with this program. Your business can access the funding without any hidden costs.

Qualifications

  • Eligible Activities: Clinical trials of natural products (e.g., botanicals, dietary supplements).
  • Scientific Premise: Must have a strong scientific premise for further testing.
  • Study Design: Trials should aim to replicate the impact on target engagement and assess functional or clinical outcomes.
  • Duration of Support: Up to 3 years support for studies.
  • Location of Business: Available across the country.
  • Sectors: Open to all sectors.
  • Employee Count: No minimum or maximum employee requirements.
  • Revenue: No minimum or maximum revenue requirements.
  • Legal Structure: All legal structures are applicable.
  • Profit Structure: All profit structures are applicable.

Disqualifications:

  • Trial Type: Does not support efficacy or effectiveness trials.

Description

This program can provide financial support for early phase clinical trials of natural products like botanicals, dietary supplements, and probiotics. You can receive up to three years of funding to conduct studies that investigate the effects of these products on human health. The tests need to be scientifically solid and aimed at producing useful results, whether they are positive or negative. This means you'll gather valuable information that can guide future research and development.

You can explore various formulations and dosages while determining how to optimize results with these natural products. This program encourages innovation, allowing you to combine these products with existing treatments to see if they can work better together. By joining this initiative, you help bridge the gap between basic science and practical applications, ultimately shedding light on whether deeper clinical research is needed.

Overall, participating in this program gives you a chance to contribute to advancements in natural health products, potentially making a significant impact in your field. You’ll be on the cutting edge of research, helping to reshape the future of healthcare.

Program Steps

  1. Visit the Program Website: Go to the official website for the program to gather detailed information and updates.

  2. Prepare the Appropriate Documentation: Collect all necessary documents needed for your application. Here’s what you’ll likely need:

    • Proof of business registration
    • A detailed project proposal outlining your clinical trial plans
    • Budget estimates for the trial
    • Evidence of scientific backing, such as previous research findings
    • Any partnership agreements (if applicable)
  3. Complete the Application Form: Fill out the application form accurately. Make sure all sections are completed as required.

  4. Submit the Application: Once you have filled in all details, submit your application by the specified deadline. Double-check that all documentation is included.

  5. Follow Up: Keep track of your application status. If there’s an option to check in, don’t hesitate to reach out for any updates.

  6. Prepare for a Possible Interview: Be ready to discuss your project in more detail. This may involve answering questions about your research and how it aligns with the program’s goals.

  7. Review and Respond to Feedback: If you receive feedback or requests for additional information, respond promptly to ensure your application remains under consideration.

Visit Program Website