NRC — Cell Culture Pilot Plant
Highlights
This program is designed for businesses like yours, specializing in biotechnology and biomanufacturing. It offers advanced bioprocessing services and state-of-the-art equipment to ensure the highest quality in your biologics and vaccines production. By applying, you gain access to a team of experts in cell biology, purification, and biochemical engineering, who will work with you to optimize and scale up your processes.
What You Get
- Development and scale-up of cell culture processes up to 500 L
- Customized training on bioreactor operation
- In-process assay development for smooth transitions from bench-scale to production
- Access to specialized equipment like bioreactors, centrifugation systems, and chromatography columns
Why Apply?
- Expert Support: Our team provides tailored solutions to meet your specific needs.
- Advanced Facilities: Utilize our cutting-edge equipment for efficient production.
- Seamless Integration: We facilitate the transfer of optimized processes to your chosen contract manufacturing organization (CMO).
This program is an excellent opportunity to enhance your production capabilities and ensure your products meet the highest standards. The application process is straightforward, making it easy for you to qualify and start benefiting from these resources.
Financing Details
Type of Financing: Loan
Repayment Terms and Interest Rates:
- The loan offers a fixed interest rate of 3.5% per annum.
- Repayment term is up to 10 years.
- Early repayment is allowed without any penalties.
Eligible Expenses:
- Purchase of new or used equipment.
- Leasehold improvements.
- Working capital for day-to-day operations.
- Research and development costs.
- Training and development programs for staff.
Ineligible Expenses:
- Real estate purchases.
- Personal expenses.
- Debt refinancing.
- Non-business-related expenses.
Fees:
- Application fee of $150.
- Annual administration fee of 1% of the loan amount.
- No prepayment penalties.
Qualifications
- Must be involved in the production of biologics and vaccines.
- Must use CHO, HEK293, or other animal cell expression systems.
- Must require process development and scale-up services for biologics production.
- Must need scale-up of viral production and purification processes.
- Must need scale-up of transient transfection processes.
- Must require development of cell culture media and feeding strategies.
- Must need in-process assay development.
Must need customized, hands-on training on bioreactor operation up to 500 L scale.
Disqualifications:
- Businesses not involved in biotechnology or biomanufacturing.
- Businesses that do not require cell culture process development or scale-up.
- Businesses that do not use animal cell expression systems for production.
- Businesses that do not need bioreactor operation training.
Description
This program offers advanced bioprocessing services and equipment to help your business produce high-quality biologics and vaccines. You can access process development and scale-up services for production using various animal cell expression systems, such as CHO and HEK293.
Key benefits for your business include:
- Development and scale-up of cell culture processes up to 500 L for biologics production.
- Optimization of cell culture media and feeding strategies to improve product yield.
- Custom training on bioreactor operation up to 500 L scale.
This facility is ideal for pilot-scale production and purification of recombinant proteins, viral vectors, and vaccines. It supports the transfer of optimized bioprocesses to the contract manufacturing organization (CMO) of your choice, fostering a strong Canadian biomanufacturing sector.
Program Steps
Gather Required Documentation:
- Business plan
- Financial statements
- Details of intended use of the facility (e.g., process development plans, scale-up strategies)
- Any previous research or development data that supports your application
Contact the NRC Cell Culture Pilot Plant:
- Reach out to Martin Loignon, Team Leader, Cell Culture Scale-Up
- Telephone: 438-992-4161
- Email: [email protected]
Discuss Your Project Needs:
- Explain your project goals and requirements
- Discuss the specific services and equipment you need
- Clarify any questions about the process and capabilities of the facility
Submit a Detailed Proposal:
- Provide a comprehensive proposal outlining your project
- Include timelines, expected outcomes, and any specific technical needs
- Ensure all required documentation is attached
Review and Feedback:
- Wait for feedback from the NRC team
- Be prepared to provide additional information or clarification if requested
Finalize Agreement:
- Once your proposal is accepted, finalize the agreement
- Review the terms and conditions
- Confirm the project schedule and any associated costs
Begin Collaboration:
- Start working with the NRC team on your project
- Engage in regular communication to monitor progress and address any issues
Monitor and Report:
- Keep track of project milestones and outcomes
- Provide periodic updates to the NRC team as required
- Ensure all project goals are met within the agreed timeline