Funding Opportunities In Us

Department of the Interior - Bureau of Land Management National Operations Center (NOC) Forest and Woodlands Resource Management Program

The Consolidated Appropriations Act of 2023 (Public Law 117-328, Sec 644) reauthorized the Japanese American Confinement Sites (JACS) Grant Program and established the Norman Y. Mineta Japanese American Confinement Education (JACE) grants, which seeks to educate the public about the historical importance of understanding Japanese American confinement in the United States during World War II, so that present and future generations may learn from Japanese American confinement and the commitment of the United States to equal justice under the law.Through a competitive grant process, the Norman Y. Mineta Japanese American Confinement Education (JACE) grants will provide financial assistance to Japanese American organizations for large impactful education projects. Up to $10 million was authorized for the life of the JACE grants. Individual awards shall be in an amount not less than $750,000. Eligible grant applicants are limited to Japanese American organizations, defined in the authorizing legislation as, “... a private nonprofit organization within the United States established to promote the understanding and appreciation of the ethnic and cultural diversity of the United States by illustrating the Japanese American experience throughout the history of the United States.” Projects must educate individuals in the United States on the historical importance of understanding Japanese American confinement during World War II, so that present and future generations may learn from Japanese American confinement and the commitment of the United States to equal justice under the law.The National Park Service seeks projects from Japanese American organizations that will have a meaningful and lasting impact on educating the public about the historical importance of understanding Japanese American confinement during World War II, so that present and future generations may learn from Japanese American confinement and the commitment of the United States to equal justice under the law.

The National Institutes of Health (NIH) awards senior individual research training fellowships to experienced scientists who wish to make major changes in the direction of their research careers or who wish to broaden their scientific background by acquiring new research capabilities as independent investigators in research fields relevant to the missions of participating NIH Institutes and Centers. This Notice of Funding Opportunity (NOFO) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial, but does allow candidates to propose research experience in a clinical trial led by a sponsor or co-sponsor.

The purpose of this Funding Opportunity Announcement (FOA) is to support hypothesis-generating research in transgender people with the objective of characterizing the biological and immunological impact of the interventions (hormones, drugs and surgical) used for gender reassignment and their impact on susceptibility to HIV and other sexually transmitted infections (STI).

See Application Package for more detailed information on Uganda Feed the Future (FTF) programs. This is not a call for applications. This is information to let the public know of USAID/Uganda's anticipated future FTF programming for FY 2010. The U.S. Government (USG) anticipates a five-year $150M commitment to be invested in programs that align directly with the goals of Uganda's Development Strategy and Investment Plan (DSIP) with a strategic focus on the maize, beans and coffee value chains.

The purpose of the National Institute for Occupational Safety and Health (NIOSH) and World Trade Center (WTC) Health Program Mentored Research Scientist Career Development Award (K01) is to provide support and 75% “protected time” (up to 3 years) for an intensive, supervised (mentored) career development experience in WTC-related health research. This can facilitate the transition of junior research scientists from the mentored to the independent stages of their careers in WTC-related health research. By providing support for the critical transition period between postdoctoral training and independent U01 or R01 funding for investigators, NIOSH/WTC Health Program hopes to foster the careers of these investigators, who are vital for the future excellence of WTC-related health research endeavors.Applicants must justify the need for a period of mentored research experience and convincingly describe how the proposed period of support will substantially enhance their careers as independent investigators. Applicants must also concisely describe the issues related to diagnostic or treatment uncertainty addressed in their proposal. Applicants should clearly articulate the anticipated impacts of the proposed research, both during the project period and beyond.The NIOSH/WTC Health Program supports K01 grants to help ensure the availability of an adequate number and diversity of highly trained scientists and educators to address issues related to diagnostic or treatment uncertainty with respect to individuals receiving monitoring and/or treatment under subtitle B of the James Zadroga 9/11 Health and Compensation Act of 2010 (Public Law 111–347, as amended by Public Laws 114–113, 116–59 and 117-328).WTC responders, screening-eligible WTC survivors, and certified-eligible WTC survivors comprise the population targeted for the research project. Research funded by the WTC Health Program is primarily intended for the benefit of the 9/11-exposed population. It is not required that project findings be generalizable to other populations.NIOSH is soliciting Mentored Research Scientist Career Development research projects within the following six major areas of clinical research interest: Translation Research, Health Services Research, Health Equity Research, Treatment Research, Prevention Research, and Quality of Life Research.The WTC Health Program Research webpage provides comprehensive information and tools for researchers. The research agenda, publication library, and other resources, including the Funding Dashboard can also be found there (e.g., awarded project details such as publications, topics, populations, funding awarded, and the principal investigators and their institutions).

Cyberspace has transformed the daily lives of people. Society's overwhelming reliance on cyberspace, however, has exposed the system's fragility and vulnerabilities: corporations, agencies, national infrastructure, and individuals continue to suffer cyber-attacks. Achieving a truly secure cyberspace requires addressing both challenging scientific and engineering problems involving many components of a system, and vulnerabilities that stem from human behaviors and choices. Examining the fundamentals of security and privacy as a multidisciplinary subject can lead to fundamentally new ways to design, build, and operate cyber systems, protect existing infrastructure, and motivate individuals to learn about cybersecurity. The Cybersecurity Enhancement Act of 2014, as amended by the National Defense Authorization Acts for 2018 and 2021, and the CHIPS and Science Act of 2022, authorizes the National Science Foundation (NSF), in coordination with the Office of Personnel Management (OPM) and the Department of Homeland Security (DHS), to offer a scholarship program to recruit and train the next generation of cybersecurity professionals to meet the needs of the cybersecurity mission of federal, state, local, and tribal governments. The goals of the CyberCorps® Scholarship for Service (SFS) program are aligned with the U.S. strategy to develop a superior cybersecurity workforce. The program goals are to: (1) increase the number of qualified and diverse cybersecurity candidates for government cybersecurity positions; (2) improve the national capacity for the education of cybersecurity professionals and research and development workforce; (3) hire, monitor, and retain high-quality CyberCorps® graduates in the cybersecurity mission of the Federal Government; and (4) strengthen partnerships between institutions of higher education and federal, state, local, and tribal governments. While all three agencies work together on all four goals, NSF’s strength is in the first two goals; OPM’s in goal (3); and DHS in goal (4). The SFS Program welcomes proposals to establish or to continue scholarship programs in cybersecurity. A proposing institution must provide clearly documented evidence of a strong existing academic program in cybersecurity. In addition to information provided in the proposal narrative, such evidence can include ABET accreditation in cybersecurity; a designation by the National Security Agency and the Department of Homeland Security as a Center of Academic Excellence in Cyber Defense Education(CAE-CDE), in Cyber Operations (CAE-CO) or in Research (CAE-R); or equivalent evidence documenting a strong program in cybersecurity. Service Obligation: All scholarship recipients must work after graduation in the cybersecurity mission of a federal, state, local, or tribal government organization, or certain other qualifying entities, for a period equal to at least the length of the scholarship. The SFS Program also supports efforts leading to an increase in the ability of the United States higher education enterprise to produce cybersecurity professionals. Funding opportunities in this area are provided via the Secure and Trustworthy Cyberspace - Education Designation (SaTC-EDU) and other programs (see the section "Increasing National Capacity in Cybersecurity Education" for more details.)

The purpose of this Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research award is to enhance the diversity of the health-related research workforce by supporting the research training of predoctoral students from diverse backgrounds including those from groups that are underrepresented in the biomedical, behavioral, or clinical research workforce. Through this award program, promising predoctoral students will obtain individualized, mentored research training from outstanding faculty sponsors while conducting well-defined research projects in scientific health-related fields relevant to the missions of the participating NIH Institutes and Centers. The proposed mentored research training is expected to clearly enhance the individual's potential to develop into a productive, independent research scientist. This Notice of Funding Opportunity (NOFO) does not allow candidates to propose to lead an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial, but does allow candidates to propose research experience in a clinical trial led by a sponsor or co-sponsor.

The FY24 TBIPHRP TRA intends to accelerate the conversion of research findings in psychological health and/or TBI into clinical applications. Funded research outcomes should lead to the development of health care products, technologies, and/or clinical practice guidelines that improve patient outcomes. Additional information about translational research can be found here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829707/ and https://ncats.nih.gov/about/about-translational-science.Applications may include preclinical applied research (including animal research) and clinical research (including pilot/exploratory clinical trials). The FY24 TBIPHRP TRA may also support ancillary studies that are associated with an ongoing or completed clinical trial and projects that optimize the design of future clinical trials. This award may not be used to support studies requiring an exception from informed consent (EFIC). Clinical trials may be designed to evaluate promising new products, pharmacologic agents (drugs or biologics), diagnostics, devices, therapies, clinical guidance, behavioral interventions, emerging approaches and technologies, and/or new indications for products currently U.S. Food and Drug Administration (FDA)-approved or -cleared.Basic research is not allowed: Basic research is defined as research directed toward greater knowledge or understanding of the fundamental aspects of phenomena and of observable facts without specific applications toward process or products in mind.Preliminary data are required: Applications must include preliminary and/or published data to support the proposed research project.The FY24 TBIPHRP TRA allows funding for a pilot/exploratory clinical trial as PART of the funded research project where limited clinical testing of a novel knowledge product,5 intervention, or device is necessary to inform the next step in clinical translation. Such pilot/exploratory clinical trial studies should be small, make up only a portion of the research proposed in the Statement of Work (SOW), and be utilized to establish the feasibility of a potential approach or to aid in device or intervention refinement. Applications that include large-scale clinical trials do not meet the intent of the mechanism. Applications that consist entirely of a pilot/exploratory clinical trial or multiple pilot/exploratory clinical trials may be administratively withdrawn.A clinical trial is defined in 45 CFR 46.102 as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials. For more information, a Human Subject Resource Document is provided at https://cdmrp.health.mil/pubs/pdf/Human%20Subjects%20Resource%20Document.pdf.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under §46.104(d)(4) of the Common Rule.Applications that include a clinical trial as part of the proposed research will have additional submission requirements and review criteria. For more information, see Section II.D.2, Content and Form of the Application Submission and Section II.E.1, Criteria. Funded clinical trials are required to post a copy of the informed consent form used to enroll subjects on a publicly available federal website in accordance with federal requirements described in 32 CFR 219.Multi-Institutional Clinical Research/Trials: As of January 20, 2020, U.S. institutions engaged in non-exempt cooperative research must rely on a single Institutional Review Board (IRB) to review and approve the portion of the research conducted at domestic sites (45 CFR 46.114(b)). If the proposed, non-exempt research involves more than one U.S.-based institution, a written plan for single IRB review arrangements must be provided at the time of application submission or award negotiation. The lead institution responsible for developing the master protocol and master consent form should be identified and should be the single point of contact for regulatory submissions and requirements.Communication and data transfer between or among the collaborating institutions, as well as how specimens and/or imaging products obtained during the study will be handled, should be included in the appropriate sections of the application. A separate intellectual and material property plan agreed on by all participating institutions is also required for multi-institutional clinical research/trials.Research Levels: The FY24 TBIPHRP TRA offers funding for two Research Levels (refer to Section II.D.5 Funding Restrictions). Only one Research Level category may be chosen per application. It is the responsibility of the applicant to select the level that aligns with the scope of the proposed research. The Research Level should be selected based on the research scope and not on the amount of the budget. The following are generalized descriptions of the scope of the research appropriate for each Research level:• Research Level 1: Research Level 1 is intended to support smaller scope, less complex preclinical and/or clinical research. Pilot clinical trials as part of the proposed research are allowed. The maximum period of performance is 3 years. The application’s direct costs budgeted for the entire period of performance should not exceed $500,000.• Research Level 2: Research Level 2 is intended to support larger scope, more complex preclinical and/or clinical research. Pilot clinical trials as part of the proposed research are allowed. The maximum period of performance is 4 years. The application’s direct costs budgeted for the entire period of performance should not exceed $1.0M.o Early-Career Investigator Partnering Option: The FY24 TBIPHRP TRA (Research Level 2 only) includes an Early-Career Investigator Partnering Option that is structured to accommodate two Principal Investigators (PIs), one of whom is an Early-Career Investigator. The combined direct costs budgeted for the entire period of performance in the applications of the Initiating PI and Partnering PI should not exceed $1.0M.o The PIs may have experience in similar or disparate scientific disciplines, but each PI is expected to bring distinct contributions to the application. One PI will be identified as the Initiating PI and will be responsible for most of the administrative tasks associated with application submission. The other investigator will be the Partnering PI. At least one of the Initiating or Partnering PIs must be an Early-Career Investigator.o The intent is not to create a mentor-mentee arrangement. Both PIs should contribute significantly to the development of the proposed research project, including the Project Narrative, Statement of Work (SOW), and other required components. The application is expected to describe how the PIs’ unique experience/expertise combined as a partnership will better address the research question, how the unique experience/expertise that each individual brings to the application is critical for the research strategy and completion of the SOW, and why the work should be done together rather than through separate efforts. o If recommended for funding, each PI will be named to an individual award within the recipient organization(s). For individual FY24 TBIPHRP TRA submission requirements for the Initiating and Partnering PI, refer toSection II.D.2, Content and Form of the Application Submission.Rigor of Preclinical Research Design: All projects should adhere to a core set of standards for rigorous study design and reporting to maximize the reproducibility and translational potential of preclinical research. The standards are described in SC Landis et al., 2012, A call for transparent reporting to optimize the predictive value of preclinical research, Nature 490:187-191 (www.nature.com/nature/journal/v490/n7419/full/nature11556.html). While these standards are written for preclinical studies, the basic principles of randomization, blinding, sample-size estimation, and data handling derive from well-established best practices in clinical studies. Projects that include research on animal models are required to submit Attachment 9, Animal Research Plan, as part of the application package to describe how these standards will be addressed. Applicants should consult the ARRIVE guidelines 2.0 (Animal Research: Reporting In Vivo Experiments) to ensure relevant aspects of rigorous animal research are adequately planned for and, ultimately, reported. The ARRIVE guidelines 2.0 can be found at https://arriveguidelines.org/arrive-guidelines.If animal models are proposed, consider the following:• Pairing clinical populations to animal models in order to validate the clinical relevance and development of prevention, assessment, and treatment solutions is encouraged.• Proposed animal models should be well justified, supported within the literature, and clearly align with clinical relevance to the human condition.Relevance to Military Health: Relevance to the health care needs of Service Members, their Families, and Veterans is a key feature of this award. Investigators are encouraged to consider the following characteristics as examples of how a project may demonstrate relevance to military health:• Explanation of how the project addresses an aspect of psychological health conditions and/or TBI that has direct relevance to the health and/or readiness of Service Members, their Families, and Veterans.• Description of how the knowledge, information, products, or technologies gained from the proposed research could be implemented in a dual-use capacity to benefit the civilian population and also address a military need.• Use of military or Veteran populations, samples, or datasets in the proposed research, if appropriate.Collaborations between researchers or consultants at military or Veterans organizations and non-military organizations are strongly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique data and research resources that the partners bring to the research effort, ultimately advancing TBI and psychological health research of significance to Service Members, their Families, and Veterans. A list of websites that may be useful in identifying additional information about ongoing DOD and VA areas of research interest or potential opportunities for collaboration can be found inAppendix 2.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $17.05M to fund approximately six TRA Research Level 1 applications and eight TRA Research Level 2 applications. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.

The U.S. National Science Foundation’s Directorate for Technology, Innovation and Partnerships (TIP) is charged with accelerating use-inspiredand translationalresearch and development (R&D) to advance U.S. competitiveness in key technology focus areas. The Breaking the Low Latency Barrier for Verticals in Next-G Wireless Networks (Breaking Low)initiative will accelerate and enable new technologies and contribute to the growth of the U.S. economy in advanced wireless communications. TIP is seeking to identify and address critical architectural, technical and technological issues that must be resolved in fifth-generation (5G) and next generation (Next-G) wireless networks to provide the necessary low-latency performance that is required for the success of key emerging vertical industries. Most current public cellular deployments are unable to support end-to-end (E2E) latencies that are consistently below 10 milliseconds (ms) and Wireless Local Area Network (WLAN) latencies below 10 ms are possible only under certain favorable conditions (low network load, high bandwidth) even with Wi Fi 6 (IEEE 802.11ax). The Next-G mobile network use cases are expected to demand even more stringent latency and reliability requirements as network designers seek to raise the bar with better performance. A closer examination of the current state of the art reveals that there are critical bottlenecks at various points in the end-to-end network path from the application to the cloud resulting from the existing design, architectural, protocol, processing, optimization and implementation choices across both control and user planes, as well as the lack of low-latency vertical applications-driven technology development. This solicitation describes an Ideas Lab focused on low-latency wireless networks and vertical applications that rely on them to: a) identify cost-effective novel approaches that have the potential to break the hurdles that exist in today’s networks, including 5G/Next-G cellular, WLAN, access and cloud components, to meet the end-to-end low-latency and high-reliability targets required to enable specific emerging vertical use cases; b) formulate and execute a coherent research and development (R&D) plan that will lead to the technological advances necessary to engineer Next-G advanced wireless networks that meet the desired low-latency and high-reliability demands of identified vertical applications; and c) prototype and demonstrate the developed technology solutions in at-scale testbeds for specific vertical use cases under a wide range of relevant network conditions. The Ideas Lab Workshop is an interactive gathering of experts and stakeholders interested in collaboratively developing potential solution approaches to a specific problem or a grand challenge. It is expected to be a three-day-long intensive and focused meeting. The participants are drawn from diverse backgrounds and a broad range of expertise areas relevant to the posed problem of interest. The goal is to facilitate a brainstorming effort among a team of experts who may not otherwise come together to solve the specific posed problem though all their experiences, expertise and the needs are very much relevant to the problem. Hence, ideally, the participants are expected not to have had significant prior research or technology development interactions among them. This Ideas Lab workshop, in particular, aims to bring together, and facilitate a dialogue among a group of innovators with diverse perspectives, experiences and expertise to stimulate creative thinking and collaborative spirit to develop and validate innovative low latency communications technologies that will help meet, and possibly exceed, Next-G mobile wireless network specifications to spur a great number of emerging applications within multiple vertical industries that will transform the way we live and interact with each other. It is expected that the participation of key stakeholders and experts from low-latency vertical application use cases in the Ideas Lab workshop, in addition to the networking/computing researchers and technical experts, may contribute to achieving the goals of this Ideas Lab program. The solicitation expects robust partnerships between both academia and industry in the wireless telecom, vertical application and cloud computing sectors to co-design solutions to meet the requirements of specific low-latency verticals including rapid prototyping, testing, validation and at-scale pilot demonstrations. It is the belief of NSF that adoption of the resultant solutions will be hastened through such partnerships and thus NSF encourages applications from both academia and industry (both wireless as well as application verticals).

The PFE: Research Initiation in Engineering Formation (PFE: RIEF) program has two goals: 1) Support research in the Professional Formation of Engineers (PFE), and 2) Increase the community of researchers conducting PFE research. PIs are expected to have little or no experience conducting social science or education research. PFE: RIEF is not intended for established researchers in engineering education or other social science fields to initiate new projects. Those researchers should consider the Research in the Formation of Engineers program (https://www.nsf.gov/funding/pgm_summ.jsp?pims_id=505681). The NSF Engineering (ENG) Directorate has launched a multi-year initiative, the Professional Formation of Engineers, to create and support an innovative and inclusive engineering profession for the 21st Century. Professional Formation of Engineers (PFE) refers to the formal and informal education and value systems by which people become engineers. It also includes the ethical responsibility of practicing engineers to sustain and grow the profession. The engineering profession must be responsive to national priorities, grand challenges, and dynamic workforce needs; it must be equally open and accessible to all. Engineering faculty possess both deep technical expertise in their engineering discipline and the primary responsibility for the process of professional formation of future engineers. As such, engineering faculty are in a unique position to help address critical challenges in engineering formation. The Professional Formation of Engineers: Research Initiation in Engineering Formation (PFE: RIEF) program enables engineering faculty who are renowned for teaching, mentoring, or leading educational reform efforts on their campus to develop expertise in conducting engineering education research.

Correctness for Scientific Computing Systems (CS2) is a joint program of the National Science Foundation (NSF) and the Department of Energy (DOE). The program addresses challenges that are both core to DOE’s mission and essential to NSF’s mission of ensuring broad scientific progress. The program’s overarching goal is to elevate correctness as a fundamental requirement for scientific computing tools and tool chains, spanning low-level libraries through complex multi-physics simulations and emerging scientific workflows. At an elementary level, correctness of a system means that desired behavioral properties will be satisfied during the system’s execution. In the context of scientific computing, correctness can be understood, at both the level of software and hardware, as absence of faulty behaviors such as excessive numerical rounding, floating-point exceptions, data races deadlocks, memory faults, violations of specifications at interfaces of system modules, and so on. The CS2 program puts correctness on an equal footing with performance, the focus of current scientific computing research. This program envisions the necessity of proving correctness even in performant scientific computing systems. Such correctness proofs themselves might rely upon multiple factors, including correctness of static and runtime program analyses. Recognizing that many scientific computing applications are inherently statistical, use probabilistic or randomized algorithms, and/or deal with uncertain data, probabilistic notions of correctness may be needed. It is also critical to realize that correctness guarantees are provided with respect to some pre-defined system model. For many reasons, including misspecification, approximation, and defect, the state space allowed by real systems might depart from that model. When this happens, the ability to probe the system to isolate the discrepancy is a key challenge in many domains. CS2 requires close and continuous collaboration between researchers in two complementary areas of expertise. One area is scientific computing, which, for this solicitation, is broadly construed to include: models and simulations of scientific theories; management and analysis of data from scientific simulations, observations, and experiments; libraries for numerical computation; and allied topics. The second area is formal reasoning and mechanized proving of properties of programs, which, for this solicitation, is broadly construed to include automatic/interactive/auto-active verification, runtime verification, type systems, abstract interpretation, programming languages, program analysis, program logic, compilers, concurrency, stochastic reasoning, static and dynamic testing, property-based testing, and allied topics.

The Geobiology and Low-Temperature Geochemistry Program supports research on geochemical processes in terrestrial Earth’s surface systems, as well as the interaction of geochemical and biological processes. Proposals may address field, laboratory, theoretical, or modeling studies of these processes and related mechanisms at all spatial and temporal scales. The Geobiology and Low-Temperature Geochemistry Program is interested in supporting transformational and cutting-edge research. The Program also supports the development of geochemical proxies and analytical techniques. The Program is highly interdisciplinary and interfaces with other programs within the Geosciences Directorate, and with programs across NSF, including in biology, chemistry, and engineering.

The National Institutes of Health (NIH) hereby notify Program Directors/Principal Investigators (PD(s)/PI(s)) holding specific types of NIH research grants listed in the full Funding Opportunity Announcement (FOA) that funds may be available for administrative supplements to meet increased costs that are within the scope of the approved award, but were unforeseen when the new or renewal application or grant progress report for non-competing continuation support was submitted. Applications for administrative supplements are considered prior approval requests (as described in Section 8.1.2.11 of the NIH Grants Policy Statement) and will be routed directly to the Grants Management Officer of the parent award. Although requests for administrative supplements may be submitted through this FOA, there is no guarantee that funds are available from the awarding IC or for any specific grant. All applicants are encouraged to discuss potential requests with the awarding IC. Additionally, prior to submission, applicants must review the awarding IC's web site to ensure they meet the IC's requirements. A list of those web sites is available at https://grants.nih.gov/grants/guide/admin_supp/index.htm.

The ER2 program supports projects that focus on what constitutes or promotes responsible and ethical research in science, technology, engineering, and mathematics (STEM) fields. The ER2 program promotes the development, improvement, and dissemination of responsible and ethical research practices and aims to build on organizational cultures that value and reward such practices. Proposers to the ER2 program may examine responsible and ethical research practices across one or more career stages. This can include, for example, the research practices of students, postdoctoral fellows, faculty, or practitioners. ER2 projects could seek to improve responsible and ethical research practices in teams, organizations, or communities, or between researchers and the public. ER2 projects may include the development of interventions that promote responsible and ethical research practices, including in multidisciplinary, inter-organizational, cross-sector, translational, or international contexts. An ER2 project can also identify challenges that undermine or erode responsible and ethical research practices in STEM fields and evaluate measures to prevent or mitigate such challenges. A comprehensive approach to responsible and ethical research not only influences individual behavior, but it also contributes to an inclusive, equitable, and respectful research culture. Thus, proposers could examine organizational or other factors that positively influence responsible and ethical research practices in STEM fields. Proposals from or involving substantial collaboration with organizations in EPSCoR-eligible jurisdictions, minority-serving institutions, women's colleges, or organizations primarily serving persons with disabilities are encouraged. Proposals that include international collaborations are encouraged if the unique resources, expertise, facilities, or locations of international partners enhance the merit of the proposed work. Please see the NSF PAPPG for guidance on international collaborations.

The objective of this NOFO is to invite sponsors of eligible water reuse projects to request cost-shared funding for planning, design, and/or construction of those projects. A NOFO for congressionally authorized Title XVI projects is being released separately. The U.S. Department of the Interior’s (Department) WaterSMART (Sustain and Manage America’s Resources for Tomorrow) Program provides a framework for Federal leadership and assistance to stretch and secure water supplies for future generations in support of the Department’s priorities. Through WaterSMART, the Bureau of Reclamation (Reclamation) leverages Federal and non-Federal funding to support stakeholder efforts to stretch scarce water supplies and avoid conflicts over water.Through the Title XVI Water Reclamation and Reuse Program (Title XVI), authorized by P.L. 102-575 in 1992, Reclamation provides financial and technical assistance to local water agencies for the planning, design, and construction of water reclamation and reuse projects. Water recycling is an important tool used to stretch limited water supplies in the Western United States. Title XVI projects develop and supplement urban and irrigation water supplies through water reuse—thereby improving efficiency, providing flexibility during water shortages, and diversifying the water supply. These projects provide growing communities with new sources of clean water which increases water management flexibility and makes water supplies more reliable. The Title XVI Program also provides support for priorities identified in Presidential Executive Order (E.O.) 14008: Tackling the Climate Crisis at Home and Abroad and aligned with other priorities, such as those identified in E.O. 13985: Advancing Racial Equity and Support for Underserved Communities Through the Federal Government. The WaterSMART Title XVI Program will advance the Biden-Harris Administration’s Justice40 Initiative. Established by E.O. 14008, the Justice40 Initiative has made it a goal that 40 percent of the overall benefits of certain federal investments, such as climate, clean energy, and other areas, flow to disadvantaged communities. Title XVI water projects are an important part of the WaterSMART Program. Eligible Projects:Planning, design, and construction of water reclamation and reuse facilities that are eligible for funding under Section 4009(c) of the WIIN Act, P.L. 114-322, are eligible projects. To be eligible for funding under this NOFO, the project must have a completed Title XVI feasibility study submitted to Reclamation for review by November 7, 2023, for applications submitted under the first submittal period and by August 30, 2024, for applications submitted under the second submittal period. Completed feasibility studies must be found by Reclamation to meet all of the requirements of WTR 11-01 by January 19, 2024, for applications submitted under the first submittal period and by November 29, 2024, for applications submitted under the second submittal period. If a feasibility study has been reviewed by Reclamation and found to meet the requirements of WTR 11-01, but the review findings have not yet been transmitted to Congress, Reclamation will transmit those findings to Congress either before project selections are made or concurrently with project selections. Eligibility does not entitle a project to any future Federal funding or create a new project authorization.The project MUST be located in one of the following States or territories: Arizona, California, Colorado, Hawaii, Idaho, Kansas, Montana, Nebraska, Nevada, New Mexico, North Dakota, Oklahoma, Oregon, South Dakota, Texas, Utah, Washington, Wyoming, American Samoa, Guam, the Northern Mariana Islands, or the Virgin Islands.All applicants should review the Full Notice of Funding Opportunity Document attached under the Related Documents tab above this statement. The Document provides full guidance and additional information on the application development process.

The purpose of this notice of funding opportunity is to invite Institutional Network Awards (U2C-TL1) to cultivate a highly integrated cohort of trainees and early career investigators and to develop career development resources to acceleratekidney, urologic, and hematologic research. To maximize integration and promote a true trainee community, Institutions are invited to submit a single, unified U2C-TL1 application to engage, recruit, prepare, and sustain the next generation of scientists able to contribute to advancing research in kidney, urology,and hematology. Applications representing multiple institutions within a single metropolitan area are strongly encouraged (see Section III.3).

Application website will be open starting August 1, 2024 Award amount is based on availability of funding. Award amount is not to exceed $300,000. Award will be based on the merit of the proposal. Proposals are due September 13, 2024. Project is to be completed by January 30, 2026 Application Website: https://nucfac-ten-year-action-plan-grant.urbanandcommunityforests.org | Link to RFP: https://nucfac.org/forms/Final%20%20NUCFAC%20RFP%206_17_2024%20ADA%20V05_.pdf | Congress established the National Urban and Community Forestry Advisory Council (Council) to advise the Secretary of Agriculture on issues related to the nations urban and community forests and related natural resources. The Council is charged by law (P.L. 95-313 Section 9 as amended through PL 110-246, [16 U.S.C. 2105](g)(1)(A)) with developing a ten-year action plan; providing annual accomplishments for the action plan and assisting the U.S. Forest Service in establishing categories and recommendations for award to the agency’s competitive National Urban and Community Forestry Challenge Cost-Share Grant Program . | The current National Urban and Community Forestry Ten-year Action plan (Action Plan) will expire at the end of 2026. To prepare for the next ten-year action plan, the Forest Service is requesting proposals from qualified organizations/entities to coordinate, facilitate and manage a collaborative and comprehensive process for the development of the next ten-year Action Plan. | | PROPOSAL REQUEST: Coordinate, facilitate, and manage a collaborative and comprehensive process for the development of the next National Urban and Community Forestry Ten Year Action Plan (2027-2037). This includes publishing and rollout assistance.   The National Urban and Community Forestry Advisory Council’s authorizing legislation requires the Council to prepare a National Urban and Community Forestry Action Plan every ten years. The current Action Plan, 2016-2026, is to be updated by January 30, 2026, for the Council to meet its mandate. | The Forest Service is seeking proposals from qualified organizations/entities to conduct a current assessment, and review and identify emerging issues of the nation’s urban forest resources and the urban and community forestry programs and activities conducted by Federal and State agencies, nonprofit organizations, community and civic organizations and other interested parties across the country. Funds are to support the development of a National Urban and Community Forestry Advisory Council’s Ten-Year Action Plan, 2027-2037 as mandated by Congress. The award will be based on the availability of funding, which may be subject to change. The maximum award amount may not to exceed $300,000. | Proposals will be expected to address the following key elements, through implementation of the scope and criteria below. This will also include incorporating the Council’s comments and recommendations. | Key Elements: 1)    Work with the National Urban and Community Forestry Advisory Council and the Forest Service Urban and Community Forestry staff throughout the process for input and guidance. 2)    Assess the current Action Plan’s accomplishments, gaps, and items to carry over into the next Action Plan. 3)    Summarize the status of urban forest resources in the United States. This is to include the human dimension of urban forestry as well as the urban natural resources. 4)    A review of urban and community forestry related programs and activities in the United States, including education and technical assistance activities conducted by: -        the Department of Agriculture, and other Federal agencies, -       the State forestry organizations, -       private industry, -       nonprofit organizations, community and civic organizations -       Indian Nation and Indigenous communities, and -       interested others. 5)    Facilitate and integrate applicable public engagement recommendations for improving the status of the Nation’s urban and community forest resources, including education and technical assistance and modifications required in existing programs and policies of relevant Federal agencies. 6)    A review of the urban and community forestry research, documents including-- a)     a review of all past five years of research and ongoing research associated with urban and community forests, arboricultural practices, urban forest management, work with disadvantaged communities, and the economic, social, and psychological benefits of trees and forest cover in urban and community environments being conducted by the Forest Service, other Federal agencies, and associated land grant colleges and universities. b)    recommendations for new and expanded research efforts directed to and by the Forest Service Research, other Federal agencies, and associated land grant colleges and universities; around urban and community forestry concerns identified by this Action Plan; and c)     a summary of research priorities and an estimate of the funds needed to implement such research, on an annual basis, by the Forest Service Research, other Federal agencies, and associated land grant colleges and universities; for the next ten years. 7)    An estimate of the financial and technical resources needed to implement the National Urban and Community Forestry Action Plan and the Urban and Community Forestry Program for the succeeding 10 fiscal years. |

The purpose of this program is to provide resources to improve the mental health outcomes for children and youth, birth through age 21, at risk for or with serious emotional disturbances (SED), and their families. This program supports the implementation, expansion, and integration of the System of Care (SOC) approach by creating sustainable infrastructure and services that are required as part of the Comprehensive Community Mental Health Services for Children and their Families Program (also known as the Children’s Mental Health Initiative or CMHI). With this program, SAMHSA aims to prepare children and youth with or at risk of SED for successful transition to adulthood and assumption of adult roles and responsibilities. | This NOFO will remain open for FY 2024 and FY 2025. | The following are the due dates for each FY: FY 2023: Applications are due by May 21, 2023 (Closed) FY 2024: Applications are due by February 14, 2024 FY 2025: Applications are due by February 14, 2025 | Applications submitted by the due date will be reviewed and funding decisions will be made by the end of the FY. | Applicants that do not receive funding are eligible to apply for the following fiscal year.

The purpose of this funding opportunity announcement (FOA) is to encourage behavioral intervention development research to test efficacy, conduct clinical trials, examine mechanisms of behavior change, determine dose-response, treatment optimization, and/or ascertain best sequencing of behavioral, combined, sequential, or integrated behavioral and pharmacological (1) drug abuse treatment interventions, including interventions for patients with comorbidities; (2) drug abuse treatment and adherence interventions; (3) drug abuse treatment and adherence interventions that utilize technologies to boost effects and increase implementability and sustainability; (4) interventions to prevent the acquisition or transmission of HIV infection among individuals in drug abuse treatment; (5) interventions to promote adherence to drug abuse treatment, HIV and addiction medications; and (6) interventions to treat substance misuse and chronic pain. Research of interest includes but is not limited to Stage II and Stage III efficacy research.

The National Institute of Mental Health (NIMH) Division of AIDS Research (DAR) encourages applications for Center Core grants (P30) to support HIV/AIDS Research Centers (ARC). The ARC is intended to provide infrastructure support that facilitates the development of high impact science in HIV/AIDS and mental health that is relevant to the NIMH mission. This Notice of Funding Opportunity (NOFO) intends to support innovative, interdisciplinary research in several areas, including basic, NeuroHIV, behavioral and social, integrated biobehavioral, applied, clinical, translational, and implementation science.

The purpose of this notice of funding opportunity (NOFO) is to inform Agency for Healthcare Research and Quality (AHRQ) grantees holding active AHRQ awards that funds may be available for administrative supplements to meet increased costs that are within the scope of the approved award, but were unforeseen when the competing application was submitted. Although requests for administrative supplements may be submitted to this NOFO, there is no guarantee that funds will be available from the awarding agency for any specific grant. Applicants are encouraged to discuss potential requests with the assigned AHRQ staff contacts for their project prior to submission.

The National Science Foundation (NSF) and the Paul G. Allen Family Foundation (the foundation) are continuing their partnership to support this program, to be administered by NSF, supporting conservation science and science-informed conservation practice in the United States. The objective of the PACSP Program is to support conservation research that investigates organismal biology, ecology, and/or evolution and is designed to contribute to the development and implementation of evidence-based activities and/or technology solutions to advance biodiversity conservation. We seek proposals that involve the implementation of conservation activitiesbased on conservation science principles via academic-conservation organization partnerships. The strongest projects will involve ongoing assessment of biodiversity outcomes, for instance via an adaptive management framework, that inform both scientific understanding and conservation actions. A significant distinction between the PACSP program and other NSF programs is that proposals to this program must make clear and well-defined connections between basic research questions and the implementation of conservation focused actions. The Program's focus is on conservation goal-related research that will directly translate to on-the-ground biodiversity conservation efforts. Proposals that adopt a convergent approach between climate and/or other anthropogenic environmental change, conservation, and the health of ecosystems and the organisms therein are especially encouraged. Proposals are also expected to incorporate project outcomes within the context of broader societal impacts and, as appropriate for the research proposed, engage non-academic partners in collaboration. For proposals recommended for funding, NSF will fund the proposed research scope and the foundation will fund the proposed conservation component of the project.

This Notice identifies the criteria established for the selection of noise mitigation project(s) under the Community Noise Mitigation Program, which is intended to facilitate the installation of sound insulation in covered facilities. Through the Consolidated Appropriations Act, 2022 (Pub. L. 117-103), $75 million in funding is available, with $56,250,000 allocated for funding at or near active-duty military installations and $18,750,000 allocated for funding at or near guard or reserve installations, of which $5 million shall be for grants to communities for which a nearby military installation has transitioned to a new type or model of aircraft after January 1, 2019. The Office of Local Defense Community Cooperation must obligate these funds through a counter-signed grant agreement no later than close of business on September 30, 2025. The Generally, a Grantee will have five (5) years after the date of the Office of Local Defense Community Cooperation award to expend the funds. If a Grantee is using the funds for non-Federal local match for grants issued by the Federal Aviation Administration under the Airport Improvement Program, the Grantee must fully execute an award with the Federal Aviation Administration within twelve (12) months of receiving a Office of Local Defense Community Cooperation award to ensure both that all Community Noise Mitigation Program grant funds are expended within five (5) years of award and all Federal Aviation Administration grant obligations are timely met. Any Grantee using Community Noise Mitigation Program funds for a Federal Aviation Administration match will agree to voluntarily terminate its Office of Local Defense Community Cooperation award if the requirement is not met. If all the funds are not awarded and obligated through this Notice of Funding Opportunity competition, the Office of Local Defense Community Cooperation may reissue a Notice of Funding Opportunity for a second competition if sufficient time remains to obligate these remaining funds prior to September 30, 2025.

This Funding Opportunity Announcement (FOA) will provide the early stage translational support needed for prototype testing/design modification, assay development for diagnostic disease targets, and development of research tools for use in the treatment of HLBS diseases and disorders. This FOA is part of a suite of Catalyze innovation grants to advance projects to the point where they can meet the entry criteria for the NHLBI Catalyze Preclinical program or attract independent development support from other federal or private partners for preclinical product optimization and characterization.

The purpose of this Notice of Funding Opportunity (NOFO) is to support research to develop and test community-level interventions to improve minority health and reduce health disparities.

The purpose of this FOA is to support the planning phase of the Model Continuums of Care Initiative (MCCI) to Advance Health Equity and End Health Disparities Among Women and Girls in Racial/Ethnic Minority and Other Underserved Communities. MCCI is a multi-ICO dissemination and implementation science initiative to advance health equity and end health disparities in racial/ethnic minority women and girls of reproductive age. Specifically, the Model Continuums of Care Initiative will apply the latest dissemination and implementationscience approaches to significantly reduce the prevalence and impact of multi-morbidity among racial/ethnic minority women and girls of reproductive age at risk and living with mental health disorders, substance use disorders, chronic stress, cardiopulmonary diseases, common metabolic disorders (e.g., diabetes), cancer, and HIV/AIDS. This concept proposes a continuum of care approach that integrates preventive health services, primary care, behavioral health, integrative care, and cardiopulmonary and endocrine specialties to fully address health care needs in each of these domains, and to have maximum impact on the overall health and well-being ofracial and ethnic minority and other underserved women and girls. While MCCI is not a maternal health initiative, women and girls ages 15-44 yrs. are centered because it is during the early reproductive period, i.e., adolescence, that multimorbidity typically begins and rapidly progresses, setting the stage for multiple chronic debilitating conditions in later life. Special emphasis will be placed on using stakeholder partnerships, provider training, and infrastructure changes to improve access for subgroups of racial/ethnic minority women and girls who currently have the least access to high quality health care (e.g., racial/ethnic minority women and girls living in low resource settings).

This Notice of Funding Opportunity (NOFO) solicits grant applications proposing exploratory research projects focused on the early-stage development of highly innovative technologies that improve the quality of the samples used for cancer research or clinical care. This includes new capabilities to address issues related to pre-analytical degradation of targeted analytes during the collection, processing, handling, and/or storage of cancer-relevant biospecimens. The overall goal is to support the development of highly innovative technologies capable of maximizing or otherwise interrogating the quality and utility of biological samples used for downstream analyses. This NOFO will support the development of tools, devices, instrumentation, and associated methods to preserve or protect sample integrity, or establish verification criteria for quality assessment/quality control and handling under diverse conditions. These technologies are expected to accelerate and/or enhance research in cancer biology, early detection and screening, clinical diagnosis, treatment, epidemiology, or address issues associated with cancer health disparities, by reducing pre-analytical variations that affect biospecimen sample quality. This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program.

The purpose of the NIH Mentored Research Scientist Development Award (K01) is to provide support and protected time (three to five years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence. Although all of the participating NIH Institutes and Centers (ICs) use this support mechanism to support career development experiences that lead to research independence, some ICs use the K01 award for individuals who propose to train in a new field or for individuals who have had a hiatus in their research career because of illness or pressing family circumstances. Other ICs use the K01 to support career development in specific fields. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor. Applicants proposing a clinical trial or an ancillary clinical trial as lead investigator, should apply to the companion NOFO.

The AFRI Foundational and Applied Science Program supports grants in six AFRI priority areas to advance knowledge in both fundamental and applied sciences important to agriculture. The six priority areas are: Plant Health and Production and Plant Products; Animal Health and Production and Animal Products; Food Safety, Nutrition, and Health; Bioenergy, Natural Resources, and Environment; Agriculture Systems and Technology; and Agriculture Economics and Rural Communities. Research-only, extension-only, and integrated research, education and/or extension projects are solicited in this Request for Applications (RFA). See Foundational and Applied Science RFA for specific detail.

The Foundational Research in Robotics (FRR) program, jointly led by the CISE and ENG Directorates, supports research on robotic systems that exhibit significant levels of both computational capability and physical complexity. For the purposes of this program, a robot is defined as intelligence embodied in an engineered construct, with the ability to process information, sense, plan, and move within or substantially alter its working environment. Here intelligence includes a broad class of methods that enable a robot to solve problems or to make contextually appropriate decisions and act upon them. The program welcomes research that considers inextricably interwoven questions of intelligence, computation, and embodiment. Projects may also focus on a distinct aspect of intelligence, computation, or embodiment, as long as the proposed research is clearly justified in the context of a class of robots. The focus of the FRR program is on foundational advances in robotics. Robotics is a deeply interdisciplinary field, and proposals are encouraged across the full range of fundamental engineering and computer science research challenges arising in robotics. To be responsive to the FRR program, each proposal should clearly articulate the following three points: The focus of the research project should be a robot or a class of robots, as defined above. [Is there a robot?] The goal of the project should be to endow a robot or a class of robots with new and useful capabilities or to significantly enhance existing capabilities. [Will a robot gain a new or significantly improved capability?] The intellectual contribution of the proposed work should address fundamental gaps in robotics. [Is robotics essential to the intellectual merit of the proposal?] Meaningful experimental validation on a physical platform is encouraged. Projects that do not represent a direct fundamental contribution to the science of robotics or are better aligned with other existing programs at NSF should not be submitted to the FRR program. Potential investigators are strongly encouraged to discuss their projects with an FRR Program Officer before submission. Non-compliant proposals may be returned without review.

The National Human Genome Research Institute (NHGRI) seeks to broaden the types of knowledge, skills, expertise, experience, and perspectives brought to bear in research addressing the ethical, legal and social implications (ELSI) of advances in human genetics or genomics. This Notice of Funding Opportunity (NOFO) solicits UM1 applications from domestic organizations located in the United States and its territories that received less than $30 million per year in total NIH funding for the past three fiscal years. These organizations are underrepresented among those receiving NHGRI funding for ELSI research. The Building Partnerships and Broadening Perspectives to Advance Ethical, Legal, and Social Implications (ELSI) Research (BPAER) Program will support: 1) transdisciplinary ELSI research addressing timely, complex, and understudied topics, 2) the establishment of research teams that include representatives from relevant communities who are affected by and have an interest in the proposed research, 3) research capacity building to develop, conduct and sustain ELSI research, and 4) workforce development opportunities for early career scholars, research team members, and other research project staff. Transdisciplinary ELSI research projects require involvement from two or more fields of knowledge and use of multiple research approaches. Relevant communities must be actively and meaningfully involved on ELSI research teams across all phases of proposed research projects. Research capacity building plans must be informed by a needs assessment. Given the complex structure, a strategic management plan, evaluation plan, and sustainability plan are required to ensure successful completion of the program.

The Healthy Communities Grant Program was launched in 2003 and supports EPA’s mission by integrating many EPA New England (Region 1) programs including Air Quality Outreach; Asthma and Indoor Air; Children’s Environmental Health; Air Pollution in Schools and the Clean, Green and Healthy Schools Initiative; Energy Efficiency Program; Environmental Justice Program; Pollution Prevention; Sustainable Materials Management; Toxics and Pesticides; and Water Infrastructure (Stormwater, Wastewater, and Drinking Water). The goal of the program is to combine available resources and best identify competitive projects that will achieve measurable environmental and public health results in communities across New England. Eligible applicants are invited to apply to EPA New England for funding consideration under this competitive grant program. The Healthy Communities Grant Program anticipates awarding approximately 15 cooperative agreements from these project applications in 2024. | The Healthy Communities Grant Program is a competitive grant program for EPA New England to fund direct work with communities to support EPA’s mission to reduce environmental risks, protect and improve human health and improve quality of life. The Healthy Communities Grant Program will achieve these goals by identifying and funding projects that: | Target resources to benefit communities at risk (environmental justice areas of potential concern and/or sensitive populations [e.g., children, elderly, tribes, urban and rural residents, and others at increased risk]). Assess, understand, and reduce environmental and human health risks. Increase collaboration through partnerships and community-based projects. Build institutional and community capacity to understand and solve environmental and human health problems. Achieve measurable environmental and human health benefits.

The goal of the Maximizing Access to Research Careers (MARC) program is to: Strengthen research training environments, and Promote broader participation in the biomedical research workforce by expanding the pool of well-trained scientists (for example, encouraging the inclusion of individuals from underrepresented groups) who: Complete their baccalaureate degree, and Transition into and complete biomedical, research-focused higher degree programs (such as Ph.D. or M.D./Ph.D.). Specifically, this funding announcement provides support to eligible, domesticorganizations to develop and implement effective, evidence-informed approaches to biomedical undergraduate training and mentoring that will keep pace with the rapid evolution of the biomedical research enterprise. NIGMS expects that the proposed research training programs will incorporate didactic, research, and career development elements to prepare trainees for careers that will have a significant impact on the health-related research needs of the nation. This program is limited to applications from baccalaureate degree-granting research-intensive organizations (that is, those with NIH Research Project Grant (RPG) funding averaging greater than or equal to $7.5 million in total costs (direct and F and A/indirect) per year over the last three fiscal years (FY)).

This Notice of Funding Opportunity Announcement (NOFO), issued by the National Institutes of Health (NIH) and the Centers for Disease Control and Prevention (CDC) invites eligible United States small businesses to submit Small Business Innovation Research (SBIR) grant applications. United States small businesses that have the research capabilities and technological expertise to contribute to the R and D mission(s) of the NIH and CDC awarding components identified in this NOFO are encouraged to submit SBIR grant applications in response to identified topics (see SBIR/STTR Program Descriptions and Research Topics for NIH, CDC, and FDA). This Parent Funding Opportunity Announcement requires that at least 1 clinical trial be proposed. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.

The Office of Disease Prevention (ODP) and participating National Institutes of Health (NIH) Institutes, Centers, and Offices (ICOs) are issuing this notice of funding opportunity (NOFO) seeking applications to test innovative approaches to implementing SBIRT/P for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities. SBIRT/P, (a term used for purposes of this funding announcement), involves screening individuals for risk of ATOD use and misuse, briefly intervening with a conversation about harmful substance use, and referring individuals for treatment or preventive services, as needed. Proposed research should include prospective tests of SBIRT/P and should leverage collaborations with healthcare and community partners. Specific research interests of participating NIH ICOs are detailed within.??

The goal of the Discovery Research PreK-12 program (DRK-12) is to catalyze research and development that enhances all preK-12 teachers’ and students’ opportunities to engage in high-quality learning experiences related to the sciences, technology, engineering, and mathematics (STEM). The program’s objectives are to: (1) build knowledge about how to develop preK-12 students’ and teachers’ STEM content knowledge, practices, and skills; (2) support collaborative partnerships among STEM education researchers, STEM education practitioners and school leaders with the goals of extending relevant scientific literatures while developing more effective practice; and (3) build the field of STEM education by supporting knowledge synthesis, interdisciplinary interactions across fields and stakeholders, and the development of novel and robust ways of assessing teacher and student learning, engagement, and skills. Outcomes of DRK-12 projects can include but are not limited to promising, evidence-based products that can be used by others to support the success of all teachers and all students (e.g., curriculum, teaching and research tools, and models of collaboration). The program solicits proposals along two strands: (1) Learning and (2) Teaching. While these strands certainly overlap and have synergy, proposals should identify one strand that is most consistent with the proposal’s objectives and research questions (e.g., are the project’s methods and outcomes focused primarily on teacher development and teaching or student development and learning?). Research project types under both Strands include exploratory, design and development, impact, implementation, measurement and assessment, and synthesis studies. The program also supports other project types including Partnership Development Grants and Workshops/Conferences. Successful proposals demonstrate how they build on fundamental research in STEM education and on previous or current applied research and development efforts. They also explain their theoretical and empirical justification (e.g., Why is the project designed as it is?) and outline related specific aims and methods with potential to yield new understandings of STEM teaching and learning contexts, processes, and outcomes. The program welcomes proposals focused on teaching and learning in any STEM field(s) and on priorities identified in the National Science Foundation’s strategic plan. Efforts focused on facilitating the reciprocal exchange or mobilization of knowledge between the research and preK-12 formal education professional communities are strongly encouraged (see this Dear Colleague Letter https://www.nsf.gov/pubs/2023/nsf23078/nsf23078.jsp).

Orthopaedic injuries have a profound impact on military readiness and return to work/activity/duty. In the military, extremity battle wounds comprise approximately 50% of injuries reported in the Department of Defense Trauma Registry. Additionally, orthopaedic injuries and conditions that occur outside of combat (e.g., during training, leisure activities, resultant from old injuries, etc.) present one of the greatest threats to the readiness of our Service Members and military. Early stabilization, treatment, and rehabilitation of orthopaedic injuries in both civilian and military populations have led to better outcomes, particularly in the prevention of secondary complications and in minimizing morbidity. Availability of orthopaedic care and treatment as early as possible, or as close to the point of injury as possible, also minimizes limb loss and affects military readiness.Although the PRORP is interested in supporting military-focused research, research supported by the PRORP is expected to also apply to all individuals who have sustained a major orthopaedic injury.With the initiation of the Arthritis Research Program, the FY24 PRORP may not fund arthritis research; however, research that addresses conditions or health abnormalities related to arthritis is permitted provided the proposed research addresses the selected Focus Area.The FY24 PRORP ARA seeks applied research applications focused on advancing optimal treatment and restoration of function for individuals with orthopaedic injuries sustained during combat and service-related activities. Applicants are encouraged to address how the proposed research will support patient care and allow patients to more quickly return to duty/work. It is expected that any research findings would also provide benefit to the general population. To meet the intent of the award mechanism, applications must specifically address an FY24 PRORP ARA Focus Area, listed in Section II.A.1, above.The FY24 PRORP ARA is focused on applied research, defined as work that refines concepts and ideas into potential solutions with a view toward evaluating technical feasibility of promising new knowledge products, pharmacologic agents, behavioral and rehabilitation interventions, diagnostic and therapeutic techniques, clinical guidance, and/or emerging approaches and technologies.Awards may not be used to support fundamental basic research. Basic research is defined as research directed toward greater knowledge or understanding of the fundamental aspects of phenomena and of observable facts without specific applications toward process or products in mind.Research Scope: Research proposed under the FY24 PRORP ARA may include small- to large-scale projects. Upon successful completion, the proposed research is expected to yield knowledge products, approaches, or technologies that have the potential to advance toward clinical translation. Strong transition plans are expected.Inclusion of preliminary and/or published data relevant to the proposed research is required. Applicants must demonstrate logical reasoning for the proposed work. To be competitive, the application must include a sound scientific rationale and a well-formulated, testable hypothesis established through a critical review and analysis of the literature.Studies allowed under the FY24 PRORP ARA may include, but are not limited to:• Refinement of concepts and ideas into potential solutions, or research tools, with a view toward evaluating technical feasibility of emerging approaches, technologies, and promising new knowledge products.• Evaluation, maturation, and/or down-selection of potential product candidates (drugs, biologic constructs, or devices/systems) in vitro and/or in vivo.• Preparation activities needed to support a future clinical trial or regulatory submission.Applications to the FY24 PRORP ARA mechanism must support preclinical applied research and may not be used for clinical research studies. Applicants seeking support for clinical research projects should consider the FY24 PRORP Clinical Translational Research Award (Funding Opportunity Number HT942524PRORPCTRA), Clinical Trial Award (Funding Opportunity Number HT942524PRORPCTA), or Women’s Health Research Award (Funding Opportunity Number HT942524PRORPWHRA) mechanisms.The funding instrument for awards made under the program announcement will be grants (31 USC 6304).Rigor of Experimental Design: All projects should adhere to a core set of standards for rigorous study design and reporting to maximize the reproducibility and translational potential of preclinical research. The standards are described in SC Landis et al., 2012, A call for transparent reporting to optimize the predictive value of preclinical research, Nature 490:187-191 (www.nature.com/nature/journal/v490/n7419/full/nature11556.html). While these standards are written for preclinical studies, the basic principles of randomization, blinding, sample-size estimation, and data handling derive from well-established best practices in clinical studies. Projects that include research on animal models are required to submit Attachment 8, Animal Research Plan, as part of the application package to describe how these standards will be addressed. Applicants should consult the ARRIVE guidelines 2.0 (Animal Research: Reporting In Vivo Experiments) to ensure relevant aspects of rigorous animal research are adequately planned for and, ultimately, reported. The ARRIVE guidelines 2.0 can be found at https://arriveguidelines.org/arrive-guidelines.Women’s Health Research: The CDMRP encourages research on health areas and conditions that affect women uniquely, disproportionately, or differently from men, including studies analyzing sex as a biological variable. Such research should relate anticipated project findings to improvements in women's health outcomes and/or advancing knowledge for women's health. Applications proposing research that solely address women’s health may also consider the FY24 PRORP WHRA mechanism, Funding Opportunity Number HT942524PRORPWHRA.Encouraged Department of Defense (DOD) and/or VA Collaboration: Military relevance is a key feature of this award. Principal Investigators (PIs) are encouraged, but not required, to collaborate with DOD or VA researchers and clinicians.Use of DOD or VA Resources: If the proposed research involves access to DOD or VA resources or databases, the application must describe the access at the time of submission and include a plan for maintaining access as needed throughout the proposed research. Refer to Section II.D.2.b.ii, Full Application Submission Components, for detailed information. Refer to the General Application Instructions, Appendix 1, for additional information.The anticipated total costs budgeted for the entire period of performance for an FY24 PRORP Applied Research Award should not exceed $750,000. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $3.75M to fund approximately five ARA applications. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.

The purpose of this Funding Opportunity Announcement (FOA) is to promote the discovery and validation of novel therapeutic targets to facilitate the development of pain therapeutics. Specifically, the focus of this FOA is on the basic science discovery of targets in the peripheral nervous system, central nervous system, immune system or other tissues in the body that can be used to develop treatments that have minimal side effects and little to no abuse/addiction liability. Research supported by this FOA must include rigorous validation studies to demonstrate the robustness of the target as a pain treatment target. This will lower the risk of adopting the target in translational projects to develop small molecules, biologics, natural substances, or devices that interact with this target for new pain treatments. Translational research to develop new medical devices are not the focus of this FOA. Basic science studies of pain and related systems in the body are responsive to this FOA and are encouraged in the context of novel pain therapeutic target discovery. This FOA is not specific for any one or group of pain conditions. Projects to identify novel targets for acute pain, chronic pain, migraine, other headache disorders, osteoarthritis, diabetic neuropathy, chemotherapy-induced neuropathy, sickle-cell pain, post stroke pain, etc. will be considered. Projects to identify novel targets for a combination of chronic overlapping pain conditions or for specific pathological conditions will be considered. Projects that seek to identify novel targets in specific populations such as women, children, older adults or other underrepresented groups will also be responsive to this FOA.

The purpose of this notice of funding opportunity (NOFO) is to understand the critical drivers of tuberculosis (TB) transmission at the individual and population levels in high-burden settings; to develop effective methods to measure rates of TB transmission that rely on an increased understanding of the biomedical basis of transmission and related risk factors; and assess potential interventions, including low-cost and low-tech options, to prevent TB transmission and detect infectious TB.

The USDA SBIR/STTR programs focus on transforming scientific discovery into products and services with commercial potential and/or societal benefit. Unlike fundamental research, the USDA SBIR/STTR programs support small businesses in the creation of innovative, disruptive technologies and enable the application of research advancements from conception into the market. The STTR program aims to foster technology transfer through formal cooperative R&D between small businesses and nonprofit research institutions.

The NHPRC seeks archival projects that will significantly improve online public discovery and use of historical records collections. We welcome projects that engage the public, expand civic education, and promote understanding of the nation’s history, democracy, and culture from the founding era to the present day. The Commission encourages projects focused on collections of America’s early legal records, such as the records of colonial, territorial, county, and early statehood and tribal proceedings that document the evolution of the nation’s legal history. Archival Projects - 2 Collections that center the voices and document the history of Black, Indigenous, and People of Color are especially welcome. In addition, with the 250th anniversary of the Declaration of Independence approaching, the Commission is particularly interested in projects that promote discovery and access to collections that explore the ideals behind our nation’s founding and the continuous debate over those ideals to the present day. Projects, to preserve and process historical records, may: ? Arrange or re-house and describe collections; ? Convert existing description for online access; ? Create new online finding aids to collections; ? Digitize historical records collections and make them freely available online. All types of historical records are eligible, including documents, photographs, born-digital records, and analog audio and moving images. The successful application will: ? demonstrate the value of the collections to the understanding of United States democracy, history, and culture; ? outline a work plan that uses archival best practices, ? be appropriately staffed with archivists; ? propose a cost-effective budget; and outline activities that connect researchers to the project’s collections, as well as the rest of the repository’s holdings. For a comprehensive list of Commission limitations on funding, please see: "What we do and do not fund". Award Information A grant is for one to two years and for up to $150,000. The Commission expects to make up to 12 grants in this category for a total of up to $1,200,000. The Commission requires that grant recipients acknowledge NHPRC grant assistance in all publicity, publications, and other products that result from its support. Eligibility Eligible applicants: ? Nonprofit organizations or institutions ? Colleges, universities, and other academic institutions ? State or local government agencies ? Federally-recognized or -acknowledged or state-recognized Native American tribes or groups Archival Projects - 3 Projects must include at least one of the eligible activities described for this program. Applications must include all required elements (SF424, Narrative, NHPRC Budget form, and Supplemental Materials). Applications that do not meet both of these criteria will not be considered. In order to ensure eligibility, applicants should first review the rules and regulations governing NHPRC grants under the Administering an NHPRC Grant section. Cost Sharing The total costs of a project are shared between the NHPRC and the applicant organization. Cost sharing is required. The applicant's financial contribution may include both direct and indirect expenses, in-kind contributions, non-Federal third-party contributions, and any income earned directly by the project. NHPRC grant recipients are not permitted to use grant funds for indirect costs (as indicated in 2 CFR 2600.101). Indirect costs must be listed under the applicant's cost sharing contribution if they are included in the budget. The Commission provides no more than 75 percent of total project costs in the Archival Projects program. For example, a grant funds request of $150,000 will require $50,000 in cost share from the applicant institution, for a total project cost of $200,000. Other Requirements Applicant organizations must be registered in the System for Award Management (SAM) prior to submitting an application, maintain SAM registration throughout the application and award process, and include a valid Unique Entity Identifier (UEI) in their application. Details on SAM registration and requesting a UEI can be found at the System for Award Management website at https://sam.gov. Please refer to the User Guides section and the Grants Registrations PDF. Ensure your SAM.gov and Grants.gov registrations and passwords are current. It may take up to one month to register or reactivate your registration with SAM.gov and Grants.gov. NHPRC will not grant deadline extensions for lack of registration.

This is an open NFO, applicants may apply to this posting or subsequent amendments for specific STEM activities. See the Related Documents tab for the full NFO, and amendments announcing new funding opportunities. | The Department of Defense (DoD) Office of the Under Secretary of Defense for Research and Engineering (OUSD(R&E)) seeks innovative applications on mechanisms to implement and research the effectiveness of STEM education, outreach, and/or workforce initiative programs, here onto referred as STEM activities. | In response to this NFO, the Department intends to release amendments and solicitations, such as Industry Days, Opportunity Days, etc., detailing funding opportunities through award(s) in STEM activities. These activities include, but are not limited to: | STEM Education and OutreachSupport for STEM Education at Two-Year Institutions/Community Colleges (2YI/CCs)Manufacturing Engineering Education ProgramEducation and Workforce Development aligned to the DoD Critical Technology AreasEnhanced Civics EducationSTEM Scholarship ProgramsStrategic PartnershipsProgram Evaluations and AssessmentsData Analytics and VisualizationsActivities aligned to the DoD STEM Strategic PlanOther NDEP Congressional Initiatives and Programs | In response to this NFO, applicants may be asked for a mandatory white paper submission, emailed to [email protected]. Use of the white paper is intended to determine which efforts are of merit preparatory to submission of a full application as described in Section IV. Applicants will be selected from the white paper submissions to be invited by the Government via email to submit a full application on Grants.gov for evaluation and possible award consideration. White papers that fail to address the areas listed in the Program Description of the NFO amendment or Industry Day/Opportunity Day announcement will not be evaluated and will not receive an invitation to submit a full technical application. | The submission of a white paper is dependent on the NFO amendment or Industry Day/Opportunity Day announcement. In addition to the submission requirements outlined in Section IV, all responses should address items in the specific NFO amendment or Industry Day/Opportunity Day announcement.

Through this funding opportunity announcement, the National Cancer Institute (NCI) solicits applications to Cancer Epidemiology Cohorts: Building the Next Generation of Research Cohorts PAR. This funding opportunity announcement seeks to support initiating and building the next generation of population-based cancer epidemiology cohorts to address specific knowledge gaps in cancer etiology and survivorship. Specifically, it will support methodological work necessary to initiate and build cancer epidemiology cohorts that can address critical scientific gaps concerning (i) new or unique exposures in relation to cancer risks and outcomes and (ii) achievement of diverse populations in cohorts with the inclusion of understudied populations (e.g., racial/ethnic groups, rural populations, and persistent poverty areas) with substantial community engagement.

The purpose of this funding announcement is to invite proposals focused on developing strategies and interventions to improve diagnostic safety in the heterogenous ambulatory care environment. AHRQ is interested in providing support designed to develop, test, and evaluate ambulatory care activities that will improve diagnostic safety and quality.

The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from Small Business Concerns (SBCs) to pursue translational activities and limited-size clinical studies to advance the development of therapeutic and diagnostic devices for disorders that affect the nervous or neuromuscular systems. Activities supported in this program include implementation of clinical prototype devices, non-clinical safety and effectivenesting, design verification and validation activities leading to submission of an Investigational Device Exemption (IDE) to the FDA or Institutional Review Board (IRB) application for a Non-Significant Risk (NSR) study. The clinical study is expected to provide information about the device function or final design that cannot be practically obtained through additional non-clinical assessments (e.g., bench top or animal studies) due to the novelty of the device or its intended use. This FOA is a milestone-driven cooperative agreement program and will involve participation of NIH program staff in negotiating the final project plan before award and monitoring of research progress. Participants in Blueprint MedTech receive funding for all activities to be conducted in their own laboratories. In addition, applicants will collaborate with NIH-funded consultants to receive assistance with specialty areas including regulatory, reimbursement, intellectual property, commercialization, and strategic partnerships. Participants can also augment their project with NIH contract research organizations that specialize in large animal testing, sterilization testing, biocompatibility assessment, manufacturing, and medical monitoring. SBCs developing their own devices or that already have established collaborations with device manufacturers are welcome to apply directly to this FOA or any of the companion opportunities. For more information see: https://neuroscienceblueprint.nih.gov/neurotherapeutics/blueprint-medtech

This funding announcement solicits R01 grant applications that propose independent research projects that are consistent with the scientific framework detailed in the 2022-2026 National Institute of Nursing Research (NINR) Strategic Plan. This research will be rooted in nursing's holistic, contextualized approach to understanding people and their health, address the nation's most pressing and persistent health challenges with a solutions orientation, and employ innovative and rigorous study designs to inform practice and policy.

The Social Psychology Program at NSF supports research and research infrastructure to advance basic knowledge in social psychology. Projects funded by the Social Psychology Program support the NSF mission to promote the progress of science; to advance the national health, prosperity and welfare; and to secure the national defense. Proposals considered by the Social Psychology Program must communicate both the intellectual merit of the science and its broader societal impacts. Proposed research should carry strong potential for creating transformative advances in the basic understanding of human social behavior. Among the many research topics supported are social cognition, attitudes, social and cultural influence, stereotypes, motivation, decision making, group dynamics, aggression, close relationships, social and affective neuroscience, social psychophysiology, emotions, prosocial behavior, health-related behavior, and personality and individual differences. Proposals that develop new theories or methods for understanding social behavior are highly encouraged. Research samples should represent substantial ranges of ethnicities, socioeconomic backgrounds, cultures and other dimensions of human populations. Interdisciplinary, multidisciplinary and convergent research approaches are encouraged. Proposals involving non-human animals are considered only if the research offers clear and direct contributions to understanding human social behavior. The program does not fund research that seeks to improve clinical practice as its primary outcome, nor does it consider proposals with disease-related goals, including work on the etiology, diagnosis or treatment of physical or mental disease, abnormality or malfunction in human beings or animals. In assessing intellectual merit, the Social Psychology Program places highest priority on research that is theoretically grounded, based on empirical observation and validation, and with designs appropriate to the questions asked. In assessing broader impacts, the Social Psychology Program places highest priority on proposals that offer strong potential to benefit society, strengthen our national security interests, improve the quality of life, broaden participation in science, enhance infrastructure for research and education, and include a plan for sharing the results with a wide variety of audiences. The Social Psychology Program expects the methods, measures and data that result from NSF support to be openly shared with other researchers and the public. For further guidance proposers should consult Data Management for NSF SBE Directorate Proposals and Awards. The Data Management Plan should articulate how the proposed research will engage with best practices of open science. Researchers are expected to engage in open science practices, and deviations from that should be well-justified. The Social Psychology Program accepts regular research proposals, including Faculty Early Career Development (CAREER) proposals, proposals for research in undergraduate institutions (RUI), rapid response research proposals (RAPID) and early-concept grants for exploratory research (EAGER). The program also accepts small conference proposals for events (including workshops) being planned one year or more after submission. The Social Psychology Program does not accept proposals for doctoral dissertation improvement awards. Investigators are encouraged to contact a Social Psychology program director before submitting a proposal to confirm its fit with the scope and priorities of the Social Psychology Program. Such contact will be most productive by sending a one-page (maximum) summary with an overview of the planned proposal, which includes a description of intellectual merit and broader impacts. The Social Psychology program is always interested in identifying new reviewers. Potential reviewers should have a Ph.D. in psychology or related field and have a demonstrated area of expertise relevant to social psychology. Individuals interested in reviewing for the program should send a short description of their areas of expertise (2 sentences) and their CV to a Social Psychology program director.

The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease. The K25 award will provide support and "protected time" for a period of supervised study and research for productive professionals with quantitative (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research.

The Statistics Program supports research in statistical theory and methods, including research in statistical methods for applications to any domain of science and engineering. The theory forms the base for statistical science. The methods are used for stochastic modeling, and the collection, analysis and interpretation of data. The methods characterize uncertainty in the data and facilitate advancement in science and engineering. The Program encourages proposals ranging from single-investigator projects to interdisciplinary team projects.

This Notice of Funding Opportunity (NOFO) aims to support research on interdisciplinary population approaches to increasing awareness of the relationship between alcohol and cancer risk, understanding and changing social norms related to alcohol consumption, developing and/or evaluating alcohol policy approaches, and the development, testing, and implementation of population-level interventions to reduce alcohol-related cancer risk. Applications that address multiple levels of consumption, such as moderate and heavy drinking, are of particular interest, as well as those focusing on alcohol use disorder (AUD) from the perspective of cancer prevention and control. Proposals addressing understudied areas are encouraged, as is attention to underrepresented minority (URM) populations experiencing cancer and alcohol-related disparities such as American Indian, Alaskan Native, and sexual and gender minority populations.

Through this Notice of Funding Opportunity (NOFO), the National Institutes of Health (NIH) aims to facilitate the career development and transition of investigators new to entrepreneurship with an interest in small business by simultaneously supporting their entrepreneurial development and the conduct of research and development under their direction. This NOFO supports small business concerns (SBCs) in employing and developing researchers as entrepreneurial Program Directors/Principal Investigators (PDs/PIs). In addition to augmenting scientific research staff and supporting research and development efforts at SBCs, a major component of this NOFO is entrepreneurial training, mentoring, and career development of the PD/PI. Optimal PDs/PIs for this award are scientists and professionals with strong research, technology development, and/or healthcare delivery skills and experience, but limited entrepreneurial and independent research project leadership experience. PDs/PIs are expected to grow their entrepreneurial skillset while working in a small business to develop promising technologies and products that align with NIH's mission to improve health and save lives.

Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required)

| This APS will focus on bilateral or regional solutions to development challenges that drive irregular migration from Central America to the United States. By grounding this APS in the Regional Development Cooperation Strategy (RDCS) for 2022-27, this APS will allow for addenda to be issued directly by countries in the Central America region, to include Mexico, Belize, Guatemala, Honduras, Costa Rica, Nicaragua, and Panama. 

The B-INSPIRE: Research on Behavioral INterventionS that Promote Careers In the Biomedical Research Enterprise Notice of Funding Opportunity (NOFO) encourages applications that propose research designed to conduct studies of behavioral interventions to enhance research-oriented individuals' interest, motivation, persistence and preparedness for careers in the biomedical research workforce. Applications that propose conducting secondary data analysis of rigorous interventions, leveraging existing intervention cohorts, using new or advanced methods of analysis of rigorous intervention datasets, or general novel combinations and integration of rigorous intervention datasets for analysis, are also encouraged. Funded projects are expected to produce research findings that will guide the implementation of behavioral interventions in a variety of academic settings and career levels to enhance the diversity of the biomedical research workforce.

The National Center for Advancing Translational Sciences (NCATS) invites applications for the Awards Supporting Cutting-Edge Technologies for Translational Science (ASCETTS) Funding Opportunity Announcement (FOA) to foster investigator-initiated development of highly innovative technologies to address barriers, limitations, or bottlenecks in translational science particularly for therapeutic development. This program will support the early-stage proof of concept, high-risk and potentially high-reward studies for feasibility and exploratory technology development, which can transform or significantly improve the efficiency of therapeutic development to achieve NCATS ultimate goals - more treatments to all people more quickly. The research proposed should be for the development of technology that can break new ground or extend present technology toward new directions or novel applications. With this initiative, we expect to support the development and/or prototyping of new technologies that will lead to improved efficiency in the therapeutic development pipeline.

Invasive surgical procedures offer the opportunity for unique intracranial interventions such as the ability to record and stimulate intracranially within precisely localized brain structures in humans. Human studies using invasive technology are often constrained by a limited number of patients and resources available to implement complex experimental protocols and need to be aggregated in a manner that addresses research questions with appropriate statistical power. Therefore, this RFA seeks applications to assemble diverse, integrated, multi-disciplinary teams that cross boundaries of interdisciplinary collaboration to overcome these fundamental barriers and to investigate high-impact questions in human neuroscience. The research should be offered as exploratory research and planning activities to establish feasibility, proof-of-principle and early-stage development that, if successful, would support, enable, and/or lay the groundwork for a potential, subsequent Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain, as described in the companion FOA (RFA-NS-22-041). Projects should maximize opportunities to conduct innovative in vivo neuroscience research made available by direct access to the brain from invasive surgical procedures. Projects should employ approaches guided by specified theoretical constructs and by quantitative, mechanistic models where appropriate. Awardees will join a consortium working group, coordinated by the NIH, to identify consensus standards of practice, including neuroethical considerations, to collect and provide data for ancillary studies, and to aggregate and standardize data for dissemination among the wider scientific community.

This notice announces the opportunity to apply for funding under the Ryan White HIV/AIDS Program (RWHAP) Part A HIV Emergency Relief Grant Program. The purpose of this program is to provide direct financial assistance to an eligible metropolitan area (EMA) or transitional grant area (TGA) that has been severely affected by the HIV epidemic. Grant funds assist eligible jurisdictions to develop or enhance access to comprehensive, high quality, community-based care for people with HIV through the provision of grant funds. The goal is to provide optimal HIV care and treatment for people with HIV and improve their medical outcomes. RWHAP Part A recipients must use these funds to provide comprehensive primary health care and support services throughout the entire designated geographic service area. Your application must address the entire service area, as defined in Appendix B. Comprehensive HIV care consists of core medical services and support services that enable people with HIV to access and remain in HIV primary medical care to improve their health outcomes. Based on an annual assessment of the services and gaps in the HIV care continuum within a jurisdiction, HIV Planning Councils/Planning Bodies (PCs/PBs) and RWHAP recipients identify specific service categories to fund. Activities in each funded service category should lead to improvements in HIV care continuum outcomes. RWHAP Part A EMAs and TGAs must use grant funds to support, further develop, and/or expand systems of care to meet the needs of people with HIV within the EMA/TGA and strengthen strategies to reach disproportionately impacted subpopulations. The Health Resources and Services Administration (HRSA) HIV/AIDS Bureau (HAB) requires EMAs/TGAs to collect and analyze data to identify needs, set priorities, make allocations, and validate the use of RWHAP funding. Your application should describe how you have used data to develop and enhance the system of care in your jurisdiction. HRSA encourages innovation and collaboration with other agencies and organizations to maximize impact on health outcomes and effectively meet the needs of people with HIV within the EMA/TGA. For more details, see Program Requirements and Expectations.

Limited Competition: Small Grant Program for NIAMS K01, K08, K23, and K25 Recipients (R03)

The purpose of this combined Broad Agency Announcement (BAA) under Federal Acquisition Regulation (FAR) Part 35 and Funding Opportunity Announcement (FOA) under 2 Code of Federal Regulations (CFR) 200.204 (henceforth referred to as “BAA”) is to solicit research proposals for submission to the U.S. Army Combat Capabilities Development Command (DEVCOM) Army Research Laboratory (ARL) for funding consideration.   Prior to this announcement, ARL announced two separate BAAs to support the mission: 1) W911NF-17-S-0002 titled “Army Research Laboratory Army Research Office Broad Agency Announcement for Fundamental Research”; and 2) W911NF-17-S-0003 titled “Army Research Laboratory Broad Agency Announcement for Basic and Applied Scientific Research”. This announcement succeeds BAA W911NF-17-S-0002 and BAA W911NF-17-S-0003 combining the opportunities into a single announcement.    ARL’s mission as the Army’s foundational research laboratory is to Operationalize Science to ensure overmatch in any future conflict. ARL’s foundational research mission spans basic research (budget activity 6.1) and applied research (budget activity 6.2) as defined by 32 CFR 22.105 but may include advanced technology development (budget activity 6.3) and advanced component development and prototypes (budget activity 6.4) when opportunities arise to directly or indirectly help achieve ARL’s mission. ARL partners across the national security enterprise to deliver fundamentally advantageous change that is rooted in the creation and exploitation of scientific knowledge.  | This publication constitutes a BAA for awards as contemplated in FAR 6.102(d)(2) and 35.016 as well as a merit-based, competitive procedure in accordance with the Department of Defense Grant and Agreement Regulations (DoDGARS) at 32 CFR 22.315(a) and the Office of the Under Secretary of Defense for Acquisition and Sustainment Other Transaction Guide version 2.0 dated July 2023. | This BAA document, and the online list of research topics found on the ARL BAA topics website at https://www.arl.devcom.army.mil/opportunities/arl-baa/, sets forth ARL’s research topics of interest for whitepapers and proposals. This BAA is issued under FAR 6.102(d)(2), which provides for the competitive selection of basic and applied research proposals, and 10 U.S.C. 4001, 10 U.S.C. 4021, and 10 U.S.C. 4022, which provide the authorities for issuing awards under this announcement for basic and applied research. The definitions of basic and applied research may be found at 32 CFR 22.105. | Proposals submitted in response to this BAA and selected for award are considered to be the result of full and open competition and in full compliance with the provision of Public Law 98-369, “The Competition in Contracting Act of 1984” and subsequent amendments. |

Hispanic Serving Institutions (HSI) are an important component of the nation’s higher education ecosystem and play a critical role in realizing the National Science Board Vision Report for a more diverse and capable science and engineering workforce. Aligned with this vision and the NSF Strategic Plan 2022 -2026 the goals of the NSF HSI Program are to: 1. Enhance the quality of undergraduate science, technology, engineering, and mathematics (STEM) education at HSIs. 2. Increase the recruitment, retention, and graduation rates of students pursuing associate’s or baccalaureate degrees in STEM at HSIs. Meeting these goals requires institutions to understand and embrace their students’ strengths, challenges, identities and lived experiences. This can happen in many ways and across many areas of an institution. As such, the IUSE: HSI program provides multiple opportunities to support an institution’s goal to become more student centered, including theEquitable Transformation in STEM Education (ETSE) competition. This competition includes the following tracks: · Departmental/Division Transformation Track (DDTT) - New · Institutional Transformation Track (ITT) · Emerging Faculty Research Track (EFRT) - New · HSI Program Resource Hubs (Hubs) This solicitation will also accept conference proposals and planning proposals, as defined by the PAPPG. The ETSE competition focuses on (1) institutional transformation projects that support HSIs in their effort to achieve equity in STEM education, and (2) the infrastructure—the HSI-Net network of resource hubs—which supports the overall program goals. Institutions are encouraged to consider how their HSI designation, and their organizational mission align to better support STEM success of all students. The ETSE competition welcomes proposals that look to implement and evaluate promising practices and/or conduct research related to broadening participation or improving recruitment, retention, graduation, and other successful outcomes in STEM undergraduate education. The ETSE solicitation supports projects designed to catalyze change and help HSIs meet students where they are, accounting for their assets and the challenges they may face. Identities and experiences are not determined solely by membership in a single monolithic population of students (e.g., Hispanic, first-generation, commuter, etc.). Consequently, institutions are expected to use institutional data to identify equity gaps, identify areas of need, and unpack the factors that shape students’ individual identities and shared experiences. The perspectives gained from this data should be central to the design of the proposed project. Please see below for specific information about each track. While proposals are focused on mechanisms for transforming undergraduate STEM education, projects should also consider student voices and include mechanisms to aggregate and analyze existing student feedback and collect quantitative and qualitative student data throughout the life of the proposed project.

Reissue of PAR-20-119. This FOA encourages applications to advance the discovery, preclinical development, and proof of concept (PoC) testing of new, rationally based candidate agents and neurostimulation approaches to treat mental disorders, substance use disorders (SUDs) or alcohol use disorder (AUD), and to develop novel ligands and circuit-engagement devices as tools to further characterize existing or to validate new drug/device targets. Partnerships between academia and industry are strongly encouraged. This FOA supports a research program of multiple projects directed toward a specific major objective, basic theme or program goal, requiring a broadly based, multidisciplinary and often long-term approach. Projects seeking support for a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies should consider the companion U01 FOA.

(Reissue of PAR-20-021) The purpose of this award is to support outstanding scientific training of highly promising postdoctoral candidates with outstanding mentors. Candidates are eligible to apply for support from this program from ~12 months prior to the start of the proposed postdoctoral position to within 12 months after starting in postdoctoral position. Based on the early timeframe of eligibility, and the discouragement of inclusion of preliminary data, this NINDS F32 seeks to foster early, goal-directed planning and to encourage applications for bold and/or innovative projects by the candidate that have the potential for significant impact. Applications are expected to incorporate strong training in quantitative reasoning and the quantitative principles of experimental design and analysis. Support by this program is limited to the first 3 years of a candidate's activity in a specific laboratory or research environment, so as to further encourage early fellowship application and timely completion of mentored training of the postdoctoral candidate in a single environment.

The U.S. Agency for International Development (USAID) Mission in Guinea is pleased to issue this APS for the implementation of an activity designed to strengthen local health systems in targeted geographic areas so that Guineans can access a higher quality of health care in their communities and local public health facilities. USAID/Guinea’s health office proposes the design of a new health sector activity entitled: Guinea Local Health System Strengthening (GLHSS). Its design involved USAID/Guinea, USAID/Washington, the Ministry of Health (MOH) and stakeholders working in the health sector. This co-engagement process will continue during the five-year implementation phase and will identify health topics on which additional information is needed. | This APS document outlines the goal, purpose, expected results, and priorities of the Guinea Local Health System Strengthening (GLHSS), and may result in multiple awards issued under subsequent APS Rounds. GLHSS in this document is an umbrella APS and will not solicit concept papers or applications. Prospective applicants will be provided a fair opportunity to develop and submit competitive concept papers to USAID for potential funding via Rounds under this APS.

The Laura Bush 21st Century Librarian Program (LB21) supports the training and professional development of library and archives professionals; developing faculty and information leaders; and recruiting, educating, and retaining the next generation of library and archives professionals in order to develop a diverse library and archival workforce and meet the information needs of their communities.

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. This Parent Funding Opportunity Announcement is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Studies conducted with specific applications toward processes or products in mind should submit under the appropriate Clinical Trials Required or Clinical Trial Optional FOA. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.

The purpose of this trans-NCI Funding Opportunity Announcement (FOA) is to promote new cancer disparities research among investigators who do not normally conduct it and to encourage the partnership of experienced cancer research investigators with cancer disparities-focused researchers. This FOA is intended to accelerate and strengthen multi-disciplinary cancer disparities research in wide ranging areas. Cancer disparities research includes, but is not limited to basic, translational, behavioral, observational, interventional, environmental and population research studies that address the adverse differences in cancer incidence, prevalence, mortality, survivorship, burden and/or response to treatment in racial/ethnic minorities and/or underserved population groups. Proposed collaborations should focus on achieving research objectives that by necessity rely on diverse and complementary expertise, technical capabilities, and resource sets. Importantly, the supplemental request is required to be within the scope of the parent award and should expand the original aims to include a cancer disparity component and possible inclusion of international comparator cohorts. A trans NCI effort, the concept reissuance of the Collaborative Program is supported by NCIs Division of Cancer Biology (DCB), Division of Cancer Treatment and Diagnosis (DCTD), Division of Cancer Prevention (DCP), Division of Cancer Control and Population Sciences (DCCPS), Center to Reduce Cancer Health Disparities (CRCHD) and now, also included Center for Global Health.

Adolescence is a critical risk period for substance use initiation and adverse outcomes related to substance use, particularly as drug use has been found to escalate between ages 12 and 19. The goal of substance use prevention efforts is to prevent and/or delay the first use of substances. Research shows that early age of onset is an important predictor for the development of a substance use disorder later in life. Further, research shows that prevention interventions can have positive long-term effects in reducing substance use. Recognizing that preventing or delaying initiation of substance use can confer important health and social benefits, the purpose of the NCI is to serve as the training and technical assistance partner for DFC and non-DFC funded community coalitions across the country by enhancing the capacity of the prevention workforce and others in the prevention community to implement evidence-based interventions.

Defense Production Act Title III Expansion of Domestic Production Capability and Capacity | In addition to the below changes, please note, this Amendment of the Funding Opportunity Announcement (FOA) suspends the submission and acceptance of White Papers until further notice. Please continue to check SAM.gov for updates. | Amendment 4, dated 12 Mar 2024, hereby updates the following Funding Opportunity Announcement (FOA) information and sections:Closing Date of the FOAFROM: 12 July 2024TO: 12 July 2025Cost CeilingFROM: $5 Billion ($2.5 Billion Government share and $2.5 Billion Recipient share)TO: $9 Billion ($4.5 Billion Government share and $4.5 Billion Recipient Share)Contracting/Agreements Points of Contact (POC)Agreements OfficerMichelle GossAgreements SpecialistMelanie KiplingerTitle III Organization [email protected] Information Full Text Announcement Sections:Section I, Paragraph 4 – ScheduleSection II, Paragraph 2 – Anticipated FundingSection X, Paragraph 3 – Support ContractorsFOA AppendicesRevised Appendix II – Sample Technology Investment Agreement (TIA)Added Appendix VII – DPA Title III Statement of Work Template/OutlineMultiple updates were also made throughout the entirety of the FOA document to correct broken hyperlinks, outdated website references, outdated Regulation references, and the removal of all physical (mailed) delivery methods of White Papers and/or Proposals.  | Amendment 3, dated 30 Mar 2022, hereby replaces FOA Amendments 1 and 2. The following FOA sections have been updated/revised: Overview InformationFull Text Announcement Sections:          IV. Open FOA (Two Step Process)            VII. FOA with Calls (One Step Process)FOA Appendices           Appendix II – Sample Technology Investment Agreement, dated 30 MAR 2022Updates were also made throughout the FOA document and Appendix II to correct broken hyperlinks and/or outdated website references | | Amendment 2 posted 28 April 2020 - Contracting POCs are changed and the mailing addresses remain the same: Please do not send anything to Sheila Titer nor Sarah Thompson. Please send to the new team shown below: | Agreements OfficerWhitney [email protected] | Agreements NegotiatorFelicia [email protected] | In the future, a revised FOA document will be provided via this site.

This Notice of Funding Opportunity announcement (NOFO) invites applications for the Clinical and Translational Science Award (CTSA) Program hubs that will be part of a national, collaborative consortium focused on bringing more treatments for all people more quickly through advancing clinical and translational science (CTS) by (1) developing, demonstrating, and disseminating scientific and operational innovations that improve the efficiency and effectiveness of clinical translation from identification to first-in-human studies to medical practice implementation to community health dissemination; (2) promoting partnerships and collaborations to facilitate and accelerate translational research projects locally, regionally, and nationally; (3) creating, providing, and disseminating innovative research programs and partnerships across institutions and communities to address health disparities and deliver the benefits of translational science to all; (4) creating and implementing scientific and operational innovations that increase the quality, safety, efficiency, effectiveness, and informativeness of clinical research; (5) providing a national resource for the rapid response to urgent public health needs; and (6) creating, providing, and disseminating CTS training for clinical research professionals of all disciplines on the research team.

This notice of funding opportunity (NOFO) seeks to support research aimed at holistic understanding of inter-individual or between-person differences in human pain conditions, focusing on Whole Person Health and enhancing pain treatment and management strategies towards personalized pain medicine. The goal of this NOFO is to support studies that focus on the collection of clinical and/or preclinical data to enable evidence-based modeling and understanding of inter-individual differences and/or heterogeneity of pain occurring with use of pain therapy/management, or with conditions such as a second pain condition, a comorbid health condition, a comorbid mental health condition, or conditions of use / misuse of opioids, alcohol or other substances. Applicants are encouraged to develop and implement novel, multidisciplinary research approaches, and include investigators with complementary expertise to fulfill the project and program goals. Input from patients and caregivers on the goals of the project is highly encouraged. Rigorous data-driven and evidence-based research approaches supported under this NOFO are expected to provide better understanding of biological and/or biopsychosocial underpinnings of inter-individual differences, heterogeneity, and stratification of persons with lived pain experience, which would accelerate the development of evidence-based solutions toward precision pain medicine.

The NIDCD is committed to identifying effective interventions for the diagnosis, prevention, or treatment of communication disorders by supporting well-designed and well-executed clinical trials. This funding opportunity announcement (FOA) supports investigator initiated low risk clinical trials addressing the mission and research interests of NIDCD. Clinical trials must meet ALL the following criteria: meet the budget limits of this FOA, not require FDA oversight, are not intended to formally establish efficacy and have low risks to potentially cause physical or psychological harm.

This program element does not have a proposal due date. Proposals may be submitted at any time, pending certain eligibility timing issues related to resubmissions and duplicate proposal avoidance, see the program element text and appropriate overview appendix (e.g., B.1 or C.1). The date shown of 3/28/2025 is the last day that proposals may be submitted subject to the ROSES-24 rules and the current Guidebook for Proposers. The ROSES-25 version of this program element is planned to overlap with this ROSES-24 version by a few weeks, allowing continuous submission of proposals across ROSES years.   Proposers must retrieve the instructions document (zip file) associated with the application package for this opportunity as there is at least one required form that must be attached to the submitted proposal package.   The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) released its annual omnibus Research Announcement (NRA), Research Opportunities in Space and Earth Sciences (ROSES) – 2024 (OMB Approval Number 2700-0092, CFDA Number 43.001) on February 14, 2024. In this case "omnibus" means that this NRA has many individual program elements, each with its own due dates and topics. All together these cover the wide range of basic and applied supporting research and technology in space and Earth sciences supported by SMD. Awards will be made as grants, cooperative agreements, contracts, and inter- or intra-agency transfers, depending on the nature of the work proposed, the proposing organization, and/or program requirements. However, most extramural research awards deriving from ROSES will be grants, and many program elements of ROSES specifically exclude contracts, because contracts would not be appropriate for the nature of the work solicited. The typical period of performance for an award is three years, but some programs may allow up to five years and others specify shorter periods. In most cases, organizations of every type, Government and private, for profit and not-for-profit, domestic and foreign (with some caveats), may submit proposals without restriction on teaming arrangements. Tables listing the program elements and due dates (Tables 2 and 3), a table that provides a very top level summary of proposal contents (Table 1), and the full text of the ROSES-2024 "Summary of Solicitation", may all be found NSPIRES at http://solicitation.nasaprs.com/ROSES2024.   This synopsis is associated with one of the individual program elements within ROSES, but this is a generic summary that is posted for all ROSES elements. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables 2 or 3 of this NRA at http://solicitation.nasaprs.com/ROSES2024table2 and http://solicitation.nasaprs.com/ROSES2024table3, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in The Lunar Data Analysis Program (NNH24ZDA001N-LDAP) one would follow the link to the NSPIRES page for that program element and then to read the text of the call one would click on “C.8 Lunar Data Analysis Program (.pdf)” to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read “C.1 Planetary Science Research Program Overview (.pdf)” from that same page. While the letters and numbers are different for each element within ROSES (A.12, B.7, etc.) the basic configuration is always the same, e.g., the letter indicates the Science Division (A is Earth Science, B is Heliophysics etc.) and whatever the letter, #1 is always the division overview.    Frequently asked questions for ROSES are posted at http://science.nasa.gov/researchers/sara/faqs. Questions concerning general ROSES-2024 policies and procedures may be directed to Max Bernstein, Lead for Research, Science Mission Directorate, at [email protected], but technical questions concerning specific program elements should be directed to the point(s) of contact for that particular element, who may be found either at the end of the individual program element in the summary table of key information or on the web list of topics and points of contact at: http://science.nasa.gov/researchers/sara/program-officers-list.   Not all program elements are known at the time of the release of ROSES. To be informed of new program elements or amendments to this NRA, proposers may subscribe to: (1) The SMD mailing lists (by logging in at http://nspires.nasaprs.com and checking the appropriate boxes under "Account Management" and "Email Subscriptions"), (2) The ROSES-2024 blog feed for amendments, clarifications, and corrections to at https://science.nasa.gov/researchers/solicitations/roses-2024/, and (3) The ROSES-2024 due date Google calendars (one for each science division). Instructions are at https://science.nasa.gov/researchers/sara/library-and-useful-links (link from the words due date calendar). 

The Institutional Research and Academic Career Development Award (IRACDA) Program provides support for a mentored postdoctoral research experience at a research-intensive institution combined with an opportunity to develop critical teaching and mentoring skills at a teaching-intensive partner institution with a diverse student population. Accordingly, the IRACDA program requires effective partnerships between a research-intensive institution and a teaching-intensive partner institution that has a historical mission or a demonstrated commitment to educating students from groups underrepresented in the biomedical research workforce.The primary goal of the IRACDA program is to develop a diverse pool of well-trained biomedical scientists who have the necessary knowledge and skills to pursue independent academic teaching and research careers. An additional goal of the IRACDA program is to benefit the teaching-intensive partner institutions, e.g., by providing research-oriented, early career teachers, mentors, and role models for the students; enhancing science educational offerings; providing research opportunities for the faculty and students; and/or bringing expertise with state-of-the-art research methods and technologies.This Funding Opportunity Announcement (FOA) does not allow appointed scholars to lead an independent clinical trial but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.

The National Center for Advancing Translational Sciences (NCATS) will award Ruth L. Kirschstein National Research Service Award (NRSA) Predoctoral Institutional Research Training Grants for the Clinical and Translational Science Awards (CTSA) Program (T32) to eligible institutions to enhance predoctoral research training of individuals seeking health professional degrees and help ensure a heterogenous pool of clinical and translational scientist trainees who are equipped with the knowledge, skills and abilities to advance diagnostics, therapeutics, clinical interventions, and behavioral modifications aimed at improving health.

The goals of the Program are to: (i) advance knowledge about the processes that force and regulate the atmosphere’s synoptic and planetary circulation, weather and climate, and (ii) sustain the pool of human resources required for excellence in synoptic and global atmospheric dynamics and climate research. Research topics include theoretical, observational and modeling studies of the general circulation of the stratosphere and troposphere; synoptic scale weather phenomena; processes that govern climate; the causes of climate variability and change; methods to predict climate variations; extended weather and climate predictability; development and testing of parameterization of physical processes; numerical methods for use in large-scale weather and climate models; the assembly and analysis of instrumental and/or modeled weather and climate data; data assimilation studies; development and use of climate models to diagnose and simulate climate and its variations and change. Some Climate and Large Scale Dynamics (CLD) proposals address multidisciplinary problems and are often co-reviewed with other NSF programs, some of which, unlike CLD, use panels in addition to mail reviewers, and thus have target dates or deadlines. Proposed research that spans in substantive ways topics appropriate to programs in other divisions at NSF, e.g., ocean sciences, ecological sciences, hydrological sciences, geography and regional sciences, applied math and statistics, etc., must be submitted at times consistent with target dates or deadlines established by those programs. If it's not clear whether your proposed research is appropriate for co-review, please contact CLD staff. CLD strongly encourages proposals from: PIs at all career stages, including through the AGS Postdoctoral Research Fellowship program. PIs at all institution types, including MSIs, non-R1 institutions, and institutions in EPSCoR jurisdictions. PIs from traditionally underrepresented groups in Atmospheric Sciences.

UPDATED NOTICE - PLEASE READ: April 6, 2023 EDA is excited to announce the launch of its new grants management platform: the Economic Development Grants Experience (EDGE). EDGE was developed to streamline the application and grants management process by implementing a single platform with increased transparency, improved user experience, higher data quality, and more efficiency throughout the entire grant lifecycle.   As of April 6th, 2023, applications can no longer be submitted on Grants.gov, and will ONLY be accepted through EDGE. To apply in EDGE, please go to: sfgrants.eda.gov. More information on how to apply is provided in the full NOFO.   PARTNERSHIP PLANNING program instructions: Please note that applicants will be invited to submit applications through EDGE for the Partnership Planning program. For more information, please reach out to your EDA point of contact. | | Program Description: EDA makes planning and local technical assistance investments to support economic development, foster job creation, and attract private investment in economically distressed areas of the United States. | Under the Planning program, EDA makes Partnership Planning, Short-Term Planning, and State Planning awards to eligible recipients to create and implement regional economic development plans designed to build capacity and guide the economic prosperity and resiliency of an area or region. More specifically, EDA makes Partnership Planning investments to designated planning organizations (i.e., District Organizations) serving EDA-designated Economic Development Districts and to Indian Tribes to facilitate the development, implementation, revision, or replacement of Comprehensive Economic Development Strategies (CEDS), which articulate and prioritize the strategic economic goals of recipients’ respective regions. EDA also makes Short-Term and State Planning awards for economic development planning activities that guide the eventual creation and retention of high-quality jobs, particularly for the unemployed and underemployed in the Nation’s most economically distressed regions. | Under the Local Technical Assistance program, EDA makes awards to strengthen the capacity of local or State organizations, institutions of higher education, and other eligible entities to undertake and promote effective economic development programs through projects such as feasibility studies, impact analyses, disaster resiliency plans, and project planning. | **Please note: While the published Notice of Funding Opportunity (available under "Related Documents") states that the ED900A form and the SF424B form are both required for a complete application, these forms are no longer required and have therefore been removed from the package template.

Methods to quantify and predict vulnerability to harmful algal blooms (HABs) has not been developed for most lakes and reservoirs in the U.S. (and the world). This limits the ability for water quality stakeholders to 1) avoid costly emergency events, 2) efficiently design source water monitoring, 3) evaluate the impact of interventions, and 4) maintain trust with the public. Current approaches for detection and prediction of harmful algal blooms rely on infrequent satellite imagery and/or water samples, and provide predictions only at specific sites (i.e., where samples are taken). Furthermore, the models used to make predictions do not typically provide an ability to diagnose the specific drivers of HABs, beyond weather variables. The challenges confronting water quality stakeholders like the USACE are to 1) improve the spatial and temporal resolution of HAB predictions; 2) have the ability to diagnose the causes of HABs in managed reservoirs. | The overarching goal of this project is to develop and test a hybrid modeling system that combines watershed, hydrodynamic and machine learning models to provide accurate predictions of HABs in USACE reservoirs, at high spatial and temporal resolution.   The products that this project will create include:   1)   A hybrid modeling system for making accurate predictions of HABs at USACE reservoirs, improving on the state-of-the-art in terms of spatial coverage and temporal frequency; 2)   Demonstrated utility of the hybrid modeling system for identifying the drivers of HABs, and for estimating the efficacy of interventions; Documentation and training to enable deployment of the hybrid modeling system at additional USCAE reservoirs.

The FY24 VRP IIRA is intended to support studies that will yield highly impactful discoveries or major advancements in the research and/or patient care of eye injury and/or visual dysfunction as related to military exposure.To support research projects at different stages and the exploration/development of ideas of different maturity levels, two different funding levels are available under this program announcement. When submitting the pre-application, it is the responsibility of the applicant organization to select the funding level that is most appropriate for the research proposed. The funding level should be selected based on the stage and maturity level of the research project, rather than the amount of the budget.• Funding Level 1 supports exploratory, innovative, high-risk/high-reward research that is in the earliest stages of idea development. Research must have the potential to yield new avenues of investigation, such as new approaches, new research tools, or new paradigms.○ Preliminary data are not required. However, applicants must provide solid rationale for the research idea, supported by literature.○ Investigators without prior experience with the visual system are welcome to submit research ideas to Funding Level 1, provided that the investigating team have sufficient expertise to test the research idea.• Funding Level 2 supports the advancement of more mature research toward clinical translation. The research idea or solution should be innovative or novel, or offer significant refinements, improvements, or new applications of existing ideas or solutions, as applicable.○ Funding Level 2 applications may focus on any phase of research from basic through translational.○ Preliminary data supporting the readiness and feasibility of the proposed research are required.○ Partnering PI Option: The FY24 VRP IIRA Funding Level 2 includes an option for two Principal Investigators (PIs). One PI will be identified as the Initiating PI andDOD FY24 Vision Investigator-Initiated Research Award 5will be responsible for the majority of the administrative tasks associated with application submission. The other PI will be identified as the Partnering PI. Both PIs should contribute significantly to the development and execution of the proposed research project. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). Each award will be subject to separate reporting, regulatory, and administrative requirements. For individual submission requirements for the Initiating and Partnering PI, refer to Section II.D.2, Content and Form of the Application Submission.Research involving human subjects and human anatomical substances is permitted; however, the IIRA may not be used to conduct clinical trials.A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that retrospectively analyze data generated from previously conducted clinical trial(s) are not considered a clinical trial.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under §46.104(d)(4) of the Common Rule.

This notice is not a mechanism to fund existing NOAA awards. The purpose of this notice is to request applications for special projects and programs associated with NOAA's strategic plan and mission goals, as well as to provide the general public with information and guidelines on how NOAA will select applications and administer discretionary Federal assistance under this Broad Agency Announcement (BAA). Each NOAA Line Office that supports financial assistance (National Marine Fisheries Service, National Ocean Service, National Weather Service, Office of Atmospheric Research, Office of Education, and National Environmental Satellite Data Information Service) has a separate BAA found in Grants.gov, so applicants should submit their application to the BAA for the Line Office that best fits their application. A description of NOAA Line Offices is found at https://www.corporateservices.noaa.gov/public/lineoffices.html and https://www.noaa.gov/office-education, and applicants may contact the Agency Contacts in Section VII. below for more information. If you submit the same application to more than one Line Office, mention this in your application and notify the relevant contacts in Section VII. so that NOAA may coordinate internally.

USAID/West Bank and Gaza - Palestinian Community Assistance ProgramPre-Solicitation Notice The United States Government (USG), through USAID, has been one of the leading donors of humanitarian assistance to the people of Gaza since the onset of military operations in December 2008. USAID assistance has focused on the delivery of food and non-food items (including clothing, household items, and hygiene kits), school and classroom supplies for private schools, and emergency supplies (blankets, plastic sheeting, and medical supplies). This assistance was a critical lifeline for the people of Gaza in the immediate aftermath of Operation Cast Lead and throughout the ensuing months. Humanitarian assistance and disaster response remain key pillars of USG support for Gaza. Additionally, USAID planning for future assistance has increasingly focused on recovery programs that both meet basic human needs and address the recovery of livelihoods for Gazan families. USAID/West Bank and Gaza will be releasing an RFA that intends to award one Cooperative Agreement to an organization that would manage and oversee humanitarian and recovery sub-grants over a multi-year period. The RFA will fund complex programming in Gaza which promotes long-term food security, safe and secure housing options, improved infrastructure, household-level economic recovery, and other economic recovery opportunities. These efforts are in line with the priorities established in the Palestinian Authority’s Early Recovery and Reconstruction Plan for Gaza. Projects funded under this RFA may include activities in the health, education, agriculture, infrastructure, or economic sectors. Examples of potential activities may include constructing agricultural infrastructure, rehabilitating irrigation systems, providing emergency food and non-food items, constructing or rehabilitating private schools/health clinics, building women’s centers, weatherizing private homes, or providing educational programming for school age children. Such activities will provide a tangible benefit to the people of Gaza in 2010 and beyond.

The National Endowment for the Humanities (NEH) Division of Research Programs is accepting applications for the Collaborative Research program. This program supports groups of two or more scholars seeking to increase humanistic knowledge through convenings, manuscript preparation for collaborative publications, the creation of scholarly digital projects, or the planning of an international collaboration. Projects must pursue significant research questions and lead to a tangible interpretive product. The work can be rooted in a single field or cross disciplines. NEH encourages collaboration with scholars working in the natural or social sciences, but projects must focus on humanistic content and employ humanistic methods.

NSF seeks proposals to create an NSF National Resource Coordination Center on Improving Undergraduate STEM Education (IUSE) (IUSE Center) that will be an intellectual partner to the IUSE: EDU community and NSF. Working in concert with the IUSE: EDU program, the goal of the IUSE Center is to serve as a focal point and intellectual partner for the IUSE: EDU community. The objectives of the IUSE Center are to: Enhance the reach and influence of IUSE investments by facilitating communication, engagement, and networking among IUSE: EDU award recipients, prospective recipients, and other stakeholders; and Provide support and resources for development and maintenance of IUSE: EDU projects, especially for prospective recipients and those underrepresented in the IUSE: EDU award recipient community. The IUSE Center will be expected to work collaboratively with NSF and the IUSE: EDU community to design, implement, and execute its activities and ensure the inclusion of diverse educators and education researchers representing the full range of the nation’s talent pool, of eligible institutions and organizations, and of STEM education efforts funded through the IUSE: EDU Program.

The purpose of the NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01) is to support comprehensive and rigorous postdoctoral research and career development experiences in the biomedical, behavioral, or clinical sciences of promising Au.D./Ph.D. audiologists who have the potential to become productive, independent investigators in scientific health-related research fields relevant to NIDCD's mission.

The NEI uses U01 cooperative agreement awards to support investigator-initiated early-stage clinical trials that are greater than minimal risk and typically are Phase I or II trials. The risk level of the U01 trial requires appropriate performance oversight and safety monitoring. For purposes of this FOA, the proposed study must be intended to evaluate interventions aimed at screening, diagnosing, preventing, or treating vision disorders.

NIGMS will support innovative educational activities designed to equip participants with technical, operational, or professional skills required for careers in the biomedical research workforce. Activities must be open to the broader biomedical research community and may focus on participants at one or more career stages from undergraduates to professionals (for example faculty, staff scientists). Funded programs will have a robust program leadership structure, participant recruitment plan, and evaluation and dissemination plans.

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated fully remotely delivered and conducted clinical trials to assess the efficacy or effectiveness of complementary and integrative health interventions in NCCIH- designated areas of high research priority. Applications submitted under this NOFO are expected to propose a remotely delivered and conducted fully powered clinical trial with no in-person contact between research staff and study participants and may utilize mHealth tools or technologies. Applicants must provide justification for the remotely delivered approach and provide preliminary data on the feasibility and safety of the approach, along with evidence that the intervention has promise of clinical benefit. Applicants are encouraged to contact the appropriate NCCIH Scientific/Research contact for the area of science for which they are planning to develop an application prior to submitting to this NOFO. This NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications that fail to include a PEDP will be considered incomplete and will be withdrawn. Applicants are strongly encouraged to read the NOFO instructions carefully and view the available PEDP guidance material.

The purpose of the NHLBI Emerging Investigator Award (EIA) is to promote scientific productivity and innovation by providing long-term support and increased flexibility to experienced Program Directors/Principal Investigators (PDs/PIs) who are currently PDs/PIs on at least two NHLBI R01-equivalent awards and whose outstanding record of research demonstrates their ability to make major contributions to heart, lung, blood and sleep (HLBS) research. The EIA is intended to support a research program, rather than a research project, by providing the primary and most likely sole source of NHLBI funding on individual grant awards. The EIA will support the research program of NHLBI-funded investigators for up to seven years. The EIA will provide investigators increased freedom to conduct research that breaks new ground or extends previous discoveries in new directions. It will also allow PDs/PIs to take greater risks and to pursue research that requires a longer timeframe. Research supported by the EIA must be within the scope of the NHLBI mission (http://www.nhlbi.nih.gov/about/org/mission).

Under this Funding Opportunity Announcement (FOA), DOL will award grants through a competitive process to organizations providing pre-apprenticeship services that support education, occupational skills training, and employment services to opportunity youth, ages 16 to 24, who are performing meaningful work and service to their communities. The YouthBuild program model prepares participants for quality jobs in a variety of careers, in diverse industry sectors, particularly in infrastructure sectors, and includes wrap-around services such as mentoring, trauma-informed care, personal counseling, transportation supports, and employment preparation - all key strategies for addressing violence in communities. YouthBuild applicants must include construction skills training and may include occupational skills training in other in-demand industries. This expansion into additional in-demand industries is the Construction Plus component. Eligible applicants for these grants are public or private non-profit agencies or organizations, including consortia of such agencies or organizations. These organizations include rural, urban, or Native American/Tribal entities that have previously served opportunity youth in a YouthBuild or other similar program. DOL will fund approximately 75 projects across the country. Individual grants will range from $700,000 to $1.5 million and require a 25 percent match from applicants, using sources other than federal funding. This FOA features a matching waiver for Tribal entities and U.S. insular areas which allows these entities to not include a match commitment in their applications. The grant period of performance for this FOA is 40 months, including a four-month planning period and a twelve-month follow-up period.

Reissue of RFA-NS-20-010: The purpose of this funding opportunity announcement (FOA) is to support preclinical optimization and development of safe, effective, and non-addictive small molecule and biologic therapeutics to treat pain. The goal of the program is to accelerate the optimization and development of promising small molecule and biologic hits/leads towards clinical trials. Applicants must have a promising hit/lead, robust biological rationale for the intended approach, and identified assays for optimization of the agent. The scope of this program includes optimization and early development activities, IND-enabling studies, and assembly of Investigational New Drug (IND) application. This is a milestone-driven phased cooperative agreement program involving participation of NIH program staff in the development of the project plan and monitoring of research progress.

The purpose of this funding opportunity announcement (FOA) is to support research on interventions to improve health in Native American (NA) populations. This includes 1) etiologic research, where there is a significant gap in knowledge, that will directly inform intervention development or adaptations, 2) research that develops, adapts, or tests the efficacy or effectiveness of health promotion and disease prevention interventions, 3) research that tests culturally informed treatment or recovery interventions and 4) where a sufficient body of knowledge on intervention efficacy exists, research on dissemination and implementation that develops and tests strategies to overcome barriers to the adoption, integration, scale-up, and sustainability of effective interventions. Existing data suggest that significant acute and chronic disease inequities exist for NA populations. Concurrently, NA populations experience unique sociopolitical, historical, and environmental stressors and risks that may exacerbate health conditions and/or impact the effectiveness of existing solutions to address the conditions. They also possess unique strengths and resiliencies that can mitigate stressors or inform intervention strategies. Through this initiative, intervention and related research is sought to build upon community knowledge, resources, and resilience to test science-based, culturally appropriate solutions to reduce morbidity and mortality through identification and remediation of precursors to diseases and disorders and through culturally informed treatment. Interventions should be designed with a consideration for sustainability within the communities where they are tested, and have the flexibility to be readily adapted, disseminated, and scaled up to other communities where culturally appropriate. For the purposes of this FOA, Native Americans include the following populations: Alaska Natives, American Indians (whose ancestral lands fall at least partially within the U.S. ma

The purpose of this Funding Opportunity Announcement (FOA) is to invite Cooperative Agreement (U24) applications for advanced development and enhancement of emerging informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology, and/or cancer health disparities. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this FOA focuses on emerging informatics technology, defined as one that has passed the initial prototyping and pilot development stage, has demonstrated potential to have a significant and broader impact, has compelling reasons for further improvement and enhancement, and has not been widely adopted in the cancer research field. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, proposed development plans must have a clear rationale on why the proposed technology is needed and how it will benefit the cancer research field. In addition, mechanisms to solicit feedback from users and collaborators throughout the development process must be included. Potential applicants who are interested in early-stage development or informatics resource sustainment should consult the companion FOAs listed above.

| This program provides up to $50 million in grant funding to eligible public bodies, non-profits, and Federally-recognized tribes. Grants may cover up to 75 percent of total project cost. There is no minimum or maximum award amount. | Grants will be provided to eligible applicants to repair eligible essential community facilities damaged by Presidentially Declared Disasters that occurred in CY 2022 . Subject to any updates to the Presidentially Declared Disasters, the following states have been identified with areas that have been impacted by qualifying events during CY 2022: Alaska, American Samoa, Arizona, California, Colorado, Florida, Hawaii, Idaho, Illinois, Iowa, Kansas, Kentucky, Maine, Massachusetts, Minnesota, Mississippi, Missouri, Montana, Nebraska, Nevada, New Mexico, New York, North Carolina, North Dakota, Oklahoma, Oregon, Puerto Rico, Rhode Island, South Carolina, South Dakota, Tennessee, Texas, U.S. Virgin Islands, Virginia, Washington, and West Virginia.   Applications for the CF Program Disaster Repair Grants must be submitted to the applicable USDA RD Office. Applications will be accepted on a continual basis, beginning on the publication date of this notice, until funds are exhausted. The applicable USDA RD State Office will conduct an initial review, rating, and selection of complete applications.

OIA is requesting proposals for Fiscal Year 2024 for the four following activities:A. Invasive Species (Activity 6),B. Revegetate Mined Lands (Activity 8), C. Native Seed Strategy for Rehabilitation and Restoration (Activity 9), and D. Advancing the National Early Detection and Rapid Response Framework: Early Detection Surveillance for Asset Protection.

Reissue of RFA-20-351.The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications to pursue invasive neural recording studies focused on mental health-relevant questions. Invasive neural recordings provide an unparalleled window into the human brain to explore the neural circuitry and neural dynamics underlying complex moods, emotions, cognitive functions, and behaviors with high spatial and temporal resolution. Additionally, the ability to stimulate, via the same electrodes, allows for direct causal tests by modulating network dynamics. This funding opportunity aims to target a gap in the scientific knowledge of neural circuit function related to mental health disorders. Researchers should target specific questions suited to invasive recording modalities that have high translational potential. Development of new technologies and therapies are outside the scope of this FOA.

The purpose of the R&E Program is to provide grants for Initiating, Restoring, or Enhancing Intercity Rail Passenger Transportation operations.

This initiative invites applications for DP1 awards to support exceptionally creative early career investigators who propose high-impact projects that lead to advances in equity across populations affected by substance use-related harms. Investigators who apply may represent various fields of research, but research projects will emphasize persistent or intractable challenges that drive disparities in medical and other consequences related to substance use and SUD across population groups.

The goals of the paleoclimate program are to: (i) provide a baseline for present climate variability and future climate trends, and (ii) improve the understanding of the physical, chemical, and biological processes that influence climate variability and trends over the long-term. Research topics include observational and modeling studies of past climate variability and its drivers and studies that develop new paleoclimate proxies and records. Competitive proposals will address specific aspects of scientific uncertainty for their proposed research. The Paleoclimate program of the Division of the Atmospheric and Geospace Sciences together with other Divisions in the Geoscience Directorate have joined in coordinating and supporting the annual Paleo Perspectives on Present and Projected Climate (P4CLIMATE) competition with the objectives to support studies within two research themes: 1) Past Regional and Seasonal Climate; and 2) Past Climate Forcing, Sensitivity, and Feedbacks. Researchers are encouraged to consider the P4CLIMATE competition as a possible source of support for their global change research. Since proposals eligible for funding in the P4CLIMATE competition are not eligible for funding in the Paleoclimate Program, researchers are strongly advised to contact the Directors of the Paleoclimate Program for guidance as to the suitability of their proposed research for either program. The paleoclimate program strongly encourages proposals from: Researchers at all career stages, including through the AGS Postdoctoral Research Fellowship program. Researchers at all institution types, including MSIs, non-R1 institutions, and institutions in EPSCoR jurisdictions. Researchers from traditionally underrepresented groups in Paleoclimate Science.

COE for Technical Training and Human Performance

The purpose of this Funding Opportunity Announcement (FOA) is to facilitate the transition of previously funded SBIR and STTR Phase II and Phase IIB projects in pain management to the commercialization stage by providing additional assistance for private partnering activities through the Commercialization Readiness Pilot (CRP) program. Specifically, this FOA supports the addition of entrepreneurial expertise into small business leadership teams along with supporting partnering activities to aid in commercialization through private third-party funding or partnership with industry.

This funding opportunity seeks to support the Comprehensive Partnerships to Advance Cancer Health Equity (CPACHE) Program. The CPACHE Program develops and maintains comprehensive, long-term, and mutually beneficial partnerships between institutions serving underserved health disparity populations and underrepresented students (ISUPSs) and NCI-designated Cancer Centers (CCs). The program aims to achieve a stronger national cancer program and address challenges in cancer and cancer disparities research, education, and outreach, as well as cancer's impact on underserved populations.The institutions in each partnership are expected to work collaboratively to: (1) increase the cancer research and cancer research education capacity of the ISUPSs; (2) promote the diversity of the cancer research workforce; (3) improve the effectiveness of CCs in developing and sustaining research programs focused on cancer health disparities and increase the number of investigators and students conducting cancer health disparities research; and (4) develop and implement cancer-related outreach and education initiatives that benefit the surrounding underserved communities.