The FOA seeks to expand the HIV/AIDS prevention toolkit among alcohol impacted populations with a range of patterns of episodic and long-term use and associated behavioral and biological risks for HIV acquisition. This includes integration of effective prevention and treatment interventions with an understanding of the overarching framework for reducing the incidence of new infections by facilitating cross-cutting informative research. This R34 Funding Opportunity Announcement (FOA) supports studies that are both necessary and sufficient to inform the planning of a clinical trial within the scope of the companion announcement HIV Prevention and Alcohol (R01 Clinical Trials Optional). The NIAAA expects that applications to this FOA will describe the planned clinical trial and in so doing demonstrate that the proposed (R34) research is scientifically necessary to design or plan the subsequent trial. Furthermore, this FOA will support research projects that are designed to provide results that will be sufficient to inform the future trial without further studies. The planned Phase II, III, or IV trial must be primarily intended to test the efficacy, safety, clinical management, or implementation of intervention(s) in the prevention of HIV. In this NIAAA funding opportunity for pilot clinical trials the R34 mechanism is intended to provide new information that answers a scientific or operational question(s) which may be pragmatic in nature and, therefore, informs the final development of a clinical trial and testing of intervention tools.
The purpose of the K01 grant program is to provide support and dedicated time for a supervised (mentored) career development experience in occupational safety and health research, leading to research independence. This grant program also is to help ensure the availability of adequate numbers of highly trained scientists and educators to address critical issues in occupational safety and health.
The purpose of this Notice of Funding Opportunity (NOFO) is to support research seeking to understand mechanisms of chemical toxicity and to identify potential molecular/genetic targets that reduce acute effects of chemical threat agents that affect the eyes and lungs. These discoveries can lead to exploration of therapeutic countermeasures through early stage development efforts supported by the Countermeasures Against Chemical Threats (CounterACT) NIH-wide program, a component within the Chemical Countermeasures Research Program (CCRP).
This is a DRAFT solicitation. Comments are due to the Point of Contact by October 1, 2024 | Proposers must retrieve the instructions document (zip file) associated with the application package for this opportunity as there is at least one required form that must be attached to the submitted proposal package. The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) released its annual omnibus Research Announcement (NRA), Research Opportunities in Space and Earth Sciences (ROSES) – 2024 (OMB Approval Number 2700-0092, CFDA Number 43.001) on February 14, 2024. In this case "omnibus" means that this NRA has many individual program elements, each with its own due dates and topics. All together these cover the wide range of basic and applied supporting research and technology in space and Earth sciences supported by SMD. Awards will be made as grants, cooperative agreements, contracts, and inter- or intra-agency transfers, depending on the nature of the work proposed, the proposing organization, and/or program requirements. However, most extramural research awards deriving from ROSES will be grants, and many program elements of ROSES specifically exclude contracts, because contracts would not be appropriate for the nature of the work solicited. The typical period of performance for an award is three years, but some programs may allow up to five years and others specify shorter periods. In most cases, organizations of every type, Government and private, for profit and not-for-profit, domestic and foreign (with some caveats), may submit proposals without restriction on teaming arrangements. Tables listing the program elements and due dates (Tables 2 and 3), a table that provides a very top level summary of proposal contents (Table 1), and the full text of the ROSES-2024 "Summary of Solicitation", may all be found NSPIRES at http://solicitation.nasaprs.com/ROSES2024. This synopsis is associated with one of the individual program elements within ROSES, but this is a generic summary that is posted for all ROSES elements. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables 2 or 3 of this NRA at http://solicitation.nasaprs.com/ROSES2024table2 and http://solicitation.nasaprs.com/ROSES2024table3, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in The Lunar Data Analysis Program (NNH24ZDA001N-LDAP) one would follow the link to the NSPIRES page for that program element and then to read the text of the call one would click on “C.8 Lunar Data Analysis Program (.pdf)” to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read “C.1 Planetary Science Research Program Overview (.pdf)” from that same page. While the letters and numbers are different for each element within ROSES (A.12, B.7, etc.) the basic configuration is always the same, e.g., the letter indicates the Science Division (A is Earth Science, B is Heliophysics etc.) and whatever the letter, #1 is always the division overview. Frequently asked questions for ROSES are posted at http://science.nasa.gov/researchers/sara/faqs. Questions concerning general ROSES-2024 policies and procedures may be directed to Max Bernstein, Lead for Research, Science Mission Directorate, at [email protected], but technical questions concerning specific program elements should be directed to the point(s) of contact for that particular element, who may be found either at the end of the individual program element in the summary table of key information or on the web list of topics and points of contact at: http://science.nasa.gov/researchers/sara/program-officers-list. Not all program elements are known at the time of the release of ROSES. To be informed of new program elements or amendments to this NRA, proposers may subscribe to: (1) The SMD mailing lists (by logging in at http://nspires.nasaprs.com and checking the appropriate boxes under "Account Management" and "Email Subscriptions"), (2) The ROSES-2024 blog feed for amendments, clarifications, and corrections to at https://science.nasa.gov/researchers/solicitations/roses-2024/, and (3) The ROSES-2024 due date Google calendars (one for each science division). Instructions are at https://science.nasa.gov/researchers/sara/library-and-useful-links (link from the words due date calendar).
The purpose of this Notice of Funding Opportunity Announcement (NOFO) is to invite R01 applications to support biomedical and behavioral research that will provide scientific data to inform the regulation of tobacco products to protect public health. Research Projects must address the research priorities related to the regulatory authority of the Food and Drug Administration (FDA) Center for Tobacco Products (CTP). The awards under this NOFO will be administered by NIH using funds that have been made available through FDA CTP and the Family Smoking Prevention and Tobacco Control Act (P.L. 111-31). Research results from this NOFO are expected to generate findings and data that are directly relevant to informing the FDA's regulation of the manufacture, distribution, and marketing of tobacco products to protect public health.
The purpose of this notice of funding opportunity (NOFO) is to provide salary support for exceptional Research Software Engineers (RSEs) that contribute their skills to the development and dissemination of biomedical, behavioral or health related software, tools, and algorithms as well as to the training of prospective users of these tools.
The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. The new tools and technologies should inform and/or exploit cell-type and/or circuit-level specificity. Plans for validating the utility of the tool/technology will be an essential feature of a successful application. The development of new genetic and non-genetic tools for delivering genes, proteins and chemicals to cells of interest or approaches that are expected to target specific cell types and/or circuits in the nervous system with greater precision and sensitivity than currently established methods are encouraged. Tools that can be used in a number of species/model organisms rather than those restricted to a single species are highly desired. Applications that provide approaches that break through existing technical barriers to substantially improve current capabilities are highly encouraged.
Amendment No. 01 Issuance Date: January 15, 2021 Subject: Notice of Funding Opportunity (NOFO) No. 72044021RFA0001 Activity Title: USAID Counter Wildlife Trafficking The purpose of Amendment No. 01 to the NOFO No. 72044021RFA0001 is to provide responses to the questions received during the questions-answers period, as specified in Attachment 1 of this Amendment. All information in the original NOFO remains unchanged and in full effect. Thank you for your interest in USAID programs. Sincerely, s/ Bruce Gelband Agreement Officer
To develop and/or pilot test interventions for HIV/AIDS-associated stigma and its outcome on the prevention and treatment of HIV/AIDS and on the quality of life of People Living with HIV/AIDS (PLWH). Specifically, this initiative will support research on or leading to interventions to address a) innovation in measurement of HIV-associated stigma and of other intersecting stigmas due to multiple morbidities to develop better interventions, b) stigma and adolescent and/or youth health, c) effects of stigma on family members or care givers of PLWH, and on the aging PLWH, d) novel stigma reduction interventions that link to increase in care-seeking behavior and/or decrease in transmission and e) coping with the complexity of added burden of stigmatization due to HIV and to one or more comorbidities/coinfections.
This Notice of Funding Opportunity (NOFO) focuses on prevention and intervention strategies for fetal alcohol spectrum disorders (FASD) throughout the lifespan. The intent of this NOFO is to support research that advances (1) prevention approaches to reduce prenatal alcohol exposure and the incidence of FASD and that (2) interventions for FASD. These objectives will be accomplished with the Exploratory/Developmental Phased Award (R61/R33) mechanism, clinical trial optional. The R61 phase will support pilot studies or secondary data analysis for hypothesis development and feasibility, and research testing the hypotheses can be expanded in the R33 phase. The transition to the R33 phase will be determined by NIAAA program staff after evaluation of the achievement of specific milestones set for the R61 phase. Highest priority will be given to applications with clinical trials. Applicants interested in planning clinical trials or adding to current projects may also consider NOFO (TEMP-23832, the R34 option).
Late-Stage Translation of Biomedical and Behavioral Research Results in Arthritis and Musculoskeletal and Skin Diseases from Academic/Non-profit Lab to Marketplace (SBIR [R43/R44] Clinical Trial Not Allowed)
The purpose of this solicitation is to provide targeted technical assistance and training support to the Government of Egypt to enable it to effectively implement a sustainable, nation-wide early grade learning (reading and mathematics) as well as develop an approach for improving the instruction of English in primary school. Over the last three years, the Ministry of Education has demonstrated strong commitment to design and scale up an Early Grade Reading Program (EGRP) that was developed in 2010 under a USAID-funded program (GILO Girls for Improved Learning Outcomes). Most recently the Ministry of Education (MOE) has decided to incorporate a mathematics component in the early grade reading program. At the same time, the Ministry would like to improve the instruction of English. Given the Ministrys strong commitment and experience, it is expected to take the lead in the US-Egypt Learning Program. The role of the grantee will be a supportive one. The grantee will solidify and build on the EGRP strategies and approaches introduced by GILO, and expand them to be fully institutionalized. Specifically the grantee will collaborate with the MOE to: (1) Strengthen early grade reading instruction, and improve mathematics and English language teaching and learning materials and instructional approaches (2) Develop cost-effective national assessments for reading and mathematics as well and monitoring and reporting systems. (3) Institutionalize pre-service and in-service professional development systems for early grade teachers and supervisors. (4) Improve the education delivery system and build the capacity of Governorate and Idara (district) teams to develop and implement education plans that include budgets for early grade learning, incentives, and needed human resources.
The purpose of this Funding Opportunity Announcement (FOA) is to stimulate efforts to translate scientific discoveries and engineering developments into methods or tools that address problems in basic research to understand disease, or in applied research to assess risk, detect, prevent, diagnose, treat, and/or manage disease. The rationale is to deliver new capabilities to meet evolving requirements for technologies and methods relevant to the advance of research and delivery of care in pre-clinical, clinical and non-clinical settings, domestic or foreign, for conditions and diseases within the missions of participating institutes.
Sample PTS Synopsis
An open competition for organizations to submit applications for a project to fight corruption in North Macedonia by maximizing whistleblower reporting and supporting implementation of its whistleblowers law. It will support whistleblowers’ role in revealing illicit practices with the aim of prompting formal investigations by the corresponding authorities. Furthermore, the project will develop a culture within public institutions whereby allegations of wrongdoing are taken seriously and investigated to hold alleged perpetrators accountable. Overall goals are to increase reports of misconduct through established channels without retribution while enforcing whistleblower protections under the law.
The objective of this funding opportunity announcement (FOA) is to stimulate research in 1) discovery and development of novel, small molecules for their potential use in studying disease treatment relevant to psychiatric disorders; and 2) to generate new insight into the biology of relevant diseases and processes that have yet to be validated as important drug targets.
This Notice of Funding Opportunity (NOFO) seeks to support multidisciplinary research teams with complementary expertise in HIV and pathobiology, pathophysiology, and/or metabolism in organs, tissues, and/or biological systems of specific interest to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). These teams will comprehensively interrogate fundamental biological mechanisms underlying HIV-associated comorbidities, co-infections, and complications relevant to the mission of the NIDDK and advance progress toward preventing or alleviating them.
This NOFO invites applications to establish and support State-based Healthcare Extension Cooperatives (referred to as Cooperatives) to conduct an initiative that is based on PCOR evidence to improve care for medically underserved people; the initiative's focus must be on behavioral healthcare. To support this initiative, the Cooperative will (1) engage key stakeholders including Medicaid agencies, managed care organizations, and other organizations that address the health needs of people who are medically underserved in identifying and addressing barriers and facilitators to implementing patient-centered healthcare delivery improvements that are based on PCOR evidence, (2) work with healthcare policy, payment, community, care delivery, and research organizations that serve people who are medically underserved to build their capacity to implement patient-centered healthcare delivery improvements based on PCOR evidence, and to support ongoing learning, (3) conduct evaluations of the Cooperative's activities and (4) provide the support structure to ensure these activities are integrated and aligned.
Addressing the Impact of Syndemics on the Health of People with HIV and Diseases and Conditions within the Missions of NIDDK and NHLBI (R01 Clinical Trial Optional)
Reissue: RFA-NS-21-024: The purpose of this Funding Opportunity Announcement (FOA) is to encourage investigators to pursue a small clinical trial to obtain critical information necessary to advance recording and/or stimulating devices to treat central nervous system disorders and better understand the human brain (e.g., Early Feasibility Study). Clinical studies supported may consist of acute or short-term procedures that are deemed Non-Significant Risk (NSR) by an Institutional Review Board (IRB), or Significant Risk (SR) studies that require an Investigational Device Exemption (IDE) from the FDA, such as chronic implants. The clinical trial should provide data to answer key questions about the function or final design of a device. This final device design may require most, if not all, of the non-clinical testing on the path to more advanced clinical trials and market approval. The clinical trial is expected to provide information that cannot be practically obtained through additional non-clinical assessments (e.g., bench top or animal studies) due to the novelty of the device or its intended use. Activities supported by this Funding Opportunity include a small clinical trial to answer key questions about the function or final design of a device. As part of the BRAIN Initiative, NIH has initiated a Public-Private Partnership Program (BRAIN PPP) that includes agreements (Memoranda of Understanding, MOU) with a number of device manufacturers willing to make such devices available, including devices and capabilities not yet market approved but appropriate for clinical research. In general it is expected that the devices' existing safety and utility data will be sufficient to enable new IRB NSR or FDA IDE approval without need for significant additional non-clinical data. For more information on the BRAIN PPP, see http://braininitiative.nih.gov/BRAIN_PPP/index.htm
The purpose of this program is to recruit and train EMS personnel in rural areas with a particular focus on addressing substance use disorders (SUD) and co-occurring disorders (COD) substance use and mental disorders. SAMHSA recognizes the great need for emergency services in rural areas and the critical role EMS personnel serve across the country. Recipients will be expected to train EMS personnel on SUD and COD, trauma-informed, recovery-based care for people with such disorders in emergency situations and, as appropriate, to maintain licenses and certifications relevant to serve in an EMS agency. With this program, SAMHSA aims to develop the capacity of EMS staff to support residents in rural communities. | This NOFO will be open for FY 2024 and FY 2025. The following are the due dates for each FY:FY 2023: Applications are due by May 1, 2023 (Closed)FY 2024: Applications are due by March 20, 2024FY 2025: Applications are due by March 20, 2025 | Applications submitted by the due date will be reviewed and funding decisions will be made by the end of the FY. | Applicants that do not receive funding are eligible to apply for the following fiscal year.
The purpose of the NHGRI Predoctoral to Postdoctoral Transition Award for a Diverse Genomics Workforce (F99/K00) is to support a defined pathway across career stages for talented graduate students from diverse backgrounds, including those from groups underrepresented in biomedical, clinical, behavioral and social sciences. This two-phased award will facilitate completion of a doctoral dissertation (F99) and transition to a strong postdoctoral research position (K00) focused on the scientific, medical, ethical, social and/or legal areas of genomics research. It is anticipated that successful completion of this phased award program will have provided students sufficient scientific and career development activities to set them on the path to becoming independent genomics researchers. This Funding Opportunity Announcement (FOA) does not allow applicants to propose to lead an independent clinical trial, but does allow applicants to propose research experience in a clinical trial led by a sponsor or co-sponsor.
The Notice of Funding Opportunity (NOFO) aims to support research addressing the interplay of autophagy orchestrated cell death and HIV pathogenesis with a focus on the CNS cellular immune responses influenced by acute and chronic drug use.
The scientific objective of this Funding Opportunity Announcement is to encourage research to delineate the role of inflammasomes in the neuropathology produced by acute or chronic drug exposure and HIV infection. Understanding the involvement of inflammasomes in virus and drug-induced immune activation may help identify molecular markers and CNS immune cells associated with HIV-1 infection or disease progression among substance abuse populations, as well as identify novel therapies to target inflammasome activation or suppression to treat neuroinflammation and immune dysregulation aroused in these processes.
Invitation: Pre-Application Conference (Amendment 5) Purpose: 1) Upload pre-application conference presentations, questions and answers, and list of participants Dear International Development Community: The United States Agency for International Development (USAID) invited organizations working on the prevention, detection, and response of infectious disease threats to participate in the pre-application conference organized by USAID’s Emerging Threats Division held on November 29, 2018, in Washington, DC. A call-in line was also available for Washington's conference. This amendment provides a copy of the PowerPoint presentations presented in the conference, questions and answers, and the list of participants. At the meeting in Washington, D.C., USAID discussed a Request for Information (RFI) provided as Annex 1 soliciting feedback from a broad range of stakeholders, including the higher education community, on a planned activity to equip current and future workforces with the multisectoral skills and competencies required to address infectious disease threats. The RFI (Appendix 1) was posted for the following purposes: 1) To obtain feedback on questions pertinent to the RFI (Appendix 1) 2) To provide industry and stakeholders an opportunity to review, comment and provide suggestions for improvement or clarification of the DRAFT Program Description for One Health Workforce Next Generation activity (Appendix 2) The comments to the Program Descriptions will not be shared; however, questions and responses as result to this RFI are made public with this amendment. Addressing infectious disease threats requires workforces that not only have the technical skills and competencies to function within their own discipline and sector, but also possess the skills to effectively and sustainably work across sectors and disciplines. USAID has invested for nearly a decade in the development of two regional OH university networks in Africa and Southeast Asia that are committed to transforming health workforces to function more effectively and across sectors: One Health Central and East Africa (OHCEA), which is based in Kampala, Uganda, and Southeast Asian One Health University Network (SEAOHUN), which is based in Chiangmai, Thailand. These networks are comprised of 144 schools and faculties in 84 universities across 12 countries. Under OHW Next Generation, USAID plans to build on this investment by strengthening the organizational capacity of these two networks to use assessments of multisectoral workforce capacity to inform the design and adaptation of training and educational offerings, develop and deliver educational offerings in alignment with prioritized One Health core competencies and technical skills, and acquire and manage direct donor funding. One cooperative agreement will be awarded to a qualified higher education institution that will represent a coalition of universities and other public and private sector organizations that will work with OHCEA and SEAOHUN, as beneficiary institutions. More information on eligibility can be found under the “Eligibility” section of this Synopsis. Thank you for your interest in USAID’s Emerging Threats Programming. THIS NOTICE IS NOT A COMMITMENT TO AWARD. All of the information contained in this Notice is subject to change.
The Centers for Disease Control/Agency for Toxic Substances and Disease Registry (CDC/ATSDR) is seeking investigator-initiated research that will identify and evaluate potential risk factors contributing to Amyotrophic Lateral Sclerosis (ALS), with preferred focus on research proposals that will examine factors related to military service, contact sports, traumatic brain injury, neuroinflammation, and infectious agents. Research proposals on preferred topics can be funded under one of three funding options, Funding Option A, Funding Option B, or Funding Option C. Funding Option A is intended to support ALS risk factor research investigations that have an existing, well substantiated evidence base and would benefit from strengthened rigorous evaluation. Funding Option B is intended to support novel ALS risk factor research investigations that may or may not have an existing evidence base, may be supported by limited and insufficient preliminary research, and are exploratory and developmental in nature. Funding Option C is intended to support research and better understanding of ALS risk including prevalence and incidence in communities such as racial and ethnic minority populations (e.g., Black or African American persons, Hispanic or Latino persons, Asian persons) and military veterans.
The SuRE program supports research capacity building at eligible higher education institutions bythrough funding investigator-initiated biomedical research inbasic, social, clinical, behavioral, or translational science that falls in the mission areas of the NIH. The purpose of SuRE awards is to provide research grant support for faculty investigators at resource-limited institutions who are not currently funded by any NIH Research Project Grants (RPGs) - with the exception of SuRE or SuRE-First awards, to furnish students with high-quality undergraduate and/or graduate research experiences and to enhance the institutional scientific research culture.
The purpose of this notice of funding opportunity (NOFO) is to support highly innovative mechanistic research to accelerate precision probiotic interventions using a milestone-driven, biphasic award mechanism, R61/R33 Phased Innovation Award. Specifically, this NOFO solicits applications that will characterize person-specific features affecting probiotic responses to identify subgroups of probiotic responders and to enhance probiotic clinical outcomes. The ultimate goal of this NOFO is to identify, understand, and develop strategies to address barriers in precision probiotic therapies to account for the heterogenicity in humans that causes inconsistent probiotic responses. The first phase, funded by the R61, will providing for up to 2 years to identify unique host biological patterns (e.g., native microbiome, immune system, gender, diet, age, genetic background, lifestyle, and health history) that are correlated with heterogeneity of probiotic clinical effects using observational or secondary data analysis studies. The second phase, funded under the R33, will support studies to assess the ability of the unique patterns determined in the R61 phase to detect the improvement of probiotic responsiveness in rigorously designed mechanistic studies in relevant animal models or in human subjects. The combined R61/R33 should not exceed 5 years. Transition from the R61 to the R33 phase of the award will be administratively reviewed and will be determined based on successful completion of Transition Milestones that need to be clearly specified in the R61 phase application. Support for a single phased award that does not need the R61 Exploratory phase is available in the companion (R33) NOFO, PAR-AT-24-XXX (TEMP-25413).
The U.S. Fish and Wildlife Service’s (FWS) mission is to work with others to conserve, protect and enhance fish, wildlife, plants, and their habitats for the continuing benefit of the American people. The International Affairs Program (IA) delivers this mission through its financial assistance programs by supporting strategic projects that deliver measurable conservation results for priority species and their habitats around the world. The Central Africa Program is administered by the Africa Branch of FWS/IA and focuses on developing the capacity of protected area and conservation managers, at multiple levels of implementation, to sustain healthy wildlife populations and benefit those communities with which they co-exist. One of the greatest threats to the wildlife populations in Central Africa is the unsustainable commercialization and trafficking of meat illegally harvested from wild populations of protected species for trade and consumption in cities. In support of the overall Central Africa Program goal and in combination with other strategies, the purpose of this Notice of Funding Opportunity is to address the threat of the unsustainable urban trade of protected species.
Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) announces its interest in supporting meritorious research projects in three distinct domains related to cancer communication: 1) the utility and application of new cancer communication surveillance approaches; 2) the development and testing of rapid cancer communication pilot interventions using innovative methods and designs; and 3) the development and testing of multilevel cancer communication models emphasizing bidirectional influence between levels. For such projects, applicants should apply communication science approaches to the investigation of behavioral targets and health outcomes related to cancer prevention and control. Applications should utilize one or more innovative communication research methodologies.
The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NIH Blueprint R25 program is to encourage individuals from diverse backgrounds, including those from groups underrepresented in the biomedical, behavioral, and clinical research workforce, to pursue further studies or careers in research. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on Courses for Skills Development, Research Experiences, and Mentoring Activities.The fully integrated educational activities should prepare undergraduate students from diverse backgrounds, including those from groups underrepresented in biomedical and behavioral sciences to enter Ph.D. degree programs in the neurosciences. To accomplish this goal, this initiative will provide institutional awards to develop neuroscience research education programs comprised of collaborative partnerships integrated across different educational institution types. Each partnership must include: a) one or more institutions that either: 1) have a historical and current mission to educate students from any of the populations that have been identified as underrepresented in biomedical research as defined by the National Science Foundation NSF, see http://www.nsf.gov/statistics/wmpd/) (i.e., African Americans or Blacks, Hispanic or Latino Americans, American Indians, Alaska Natives, Native Hawaiians, U.S. Pacific Islanders, and persons with disabilities) or 2) have a documented track record of recruiting, training and/or educating, and graduating underrepresented students as defined by NSF (see above), which has resulted in increasing the institution's contribution to the national pool of graduates from underrepresented backgrounds who pursue biomedical research careers; b) a research-intensive institution that has an established neuroscience or neuroscience-related program; c) integrated
The U.S. Department of Housing and Urban Development (HUD), Office of Policy Development and Research (PD&R) issues this Notice to announce that it has authority to accept unsolicited research proposals that address the current research priorities, which are included in this Notice. In accordance with statutory requirements, the research proposals must be submitted by eligible applicants and provide cost sharing of at least 50 percent of total project cost from philanthropic entities or Federal, state, or local government agencies. This Notice also announces that HUD is accepting research proposals for such research partnerships and provides a general description of information that should be included in any research proposal. Any organization that expects to submit a proposal to HUD should carefully read all information in this Notice to avoid sending an incomplete or ineligible proposal. Failure to respond accurately to any submission requirement could result in an incomplete or ineligible proposal.For further information regarding this Notice, direct questions regarding the specific requirements of this Notice to the agency contact identified in section VII.
The primary purpose of the NIH Mentored Clinical Scientist Research Career Development Awards (K08) program is to prepare qualified individuals for careers that have a significant impact on the health-related research needs of the Nation. This program represents the continuation of a long-standing NIH program that provides support and "protected time" to individuals with a clinical doctoral degree for an intensive, supervised research career development experience in the fields of biomedical and behavioral research, including translational research.
The Stimulating Urology Interdisciplinary Team Opportunity Research (SUITOR) program is intended to promote innovative, high quality, interdisciplinary research relevant to the mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The NIDDK invites investigator-initiated research project grant applications (R01s) in specific areas of basic, translational, or clinical research in specific benign urologic conditions and diseases where needs and opportunities for progress are particularly timely. As such, research topics of interest will change over time to take advantage of emerging opportunities. The research topic area previously supported by the SUITOR program, urinary incontinence, will now transition to neurourology, as described below.
Avenir means future in French, and the Avenir Award Program for Research on Substance Abuse and HIV/AIDS looks toward the future by supporting early stage investigators (ESI) proposing highly innovative studies that address NIH HIV/AIDS Research Priorities https://grants.nih.gov/grants/guide/notice-files/NOT-OD-15-137.html. The Avenir Award Program for Research on Substance Abuse and HIV/AIDS will support creative individuals who wish to pursue innovative research at the nexus of substance abuse and HIV/AIDS. The nexus with drug abuse should be clearly described. The Avenir Award Program for Research on Substance Abuse and HIV/AIDS will support research approaches, both basic and clinical, which have the potential to benefit substance using populations with or at risk for HIV/AIDS by reducing HIV incidence, improving therapies for HIV, reducing the impact of comorbid conditions, and ultimately, eradicating HIV.
National Leadership Grants for Museums support projects that address critical needs of the museum field and that have the potential to advance practice in the profession to strengthen museum services for the American public.
The Biosensing program is part of the Engineering Biology and Health cluster, which also includes 1) the Biophotonics program; 2) the Cellular and Biochemical Engineering program; 3) the Disability and Rehabilitation Engineering program; and 4) the Engineering of Biomedical Systems program. The Biosensing program supports fundamental engineering research in the monitoring, identification and/or quantification of biological analytes and phenomena using innovations that exist at the intersection of engineering, life sciences, and information technology. Projects submitted to the program must advance both engineering and life sciences. The Biosensing program encourages proposals that, in addition to advancing biosensing technology, address critical sensor needs in biomedical research, public health, food safety, agriculture, forensics, environmental protection, and homeland security. Proposals are especially encouraged in areas of critical need: sensing technologies that can enable monitoring and surveillance of the environment and/or individuals for novel infectious agents; platform technologies that can readily be modified as soon as new agents are detected, sequenced, and/or otherwise characterized to enable rapid deployment of sensors in clinics and the environment; and adaptive and/or multiplex sensing technologies that can help the nation prevent the spread of the next global pandemic. Major areas of interest for the program include: Novel signal transduction principles and mechanisms that enable sensitive and specific biosensors, suitable for measurements in multiple areas; Design of novel biorecognition elements and appropriately designed transducing systems to enable adaptable and/or reconfigurable operating parameters in response to environmental changes or application needs at levels of device, system, or data analysis; Development of adaptive and/or evolvable biosensing systems for detection of novel target analytes or analytes under novel conditions; Novel synthetic biology approaches for the development of cell-free and cell-based biosensors; and Combining biosensors with artificial intelligence (AI) methods to improve sensor specificity and response time. Innovative ideas outside of the above specific interest areas may be considered. However, prior to submission, it is recommended that the PI contact the program director to avoid the possibility of the proposal being returned without review. The Biosensors program does not encourage proposals addressing circuit design for signal processing and amplification, computational modeling, and microfluidics for sample separation and filtration. Medical imaging-based measurements are outside of the scope of the program interests. Proposals that rely heavily on descriptive approaches are given lower priority. Proposals for optimizing and/or utilizing established methods for specific applications should be directed to programs focused on the application of sensor technology. NOTE: Projects related to water and/or soil quality may be jointly supported with the Environmental Engineering program (CBET 1440). Photonic devices with medical imaging and/or optogenetics should be submitted to the Biophotonics program (CBET 7236). Applications of devices for tissue engineering or organ-on-chip systems should be submitted to the Engineering of Biomedical Systems program (CBET 5345). Basic chemical/biochemical sensing mechanisms should be submitted to the Chemical Measurement and Imaging program (CMI 6880) in the Division of Chemistry. Proposals for dynamic biosensing systems, including circuit design for signal/data processing and amplification, and sensing systems through communication and machine learning should be submitted to the Communications, Circuits, and Sensing-Systems program (CCSS 7564) in the Division of Electrical, Communications, and Cyber Systems. INFORMATION COMMON TO MOST CBET PROGRAMS Proposals should address the novelty and/orpotentially transformative natureof the proposed work compared to previous work in the field.Also, it is important to address why the proposed work is important in terms of engineering science, as well as to also project the potential impact on society and/or industry of success in the research.The novelty or potentially transformative nature of the research should be included, as a minimum, in the Project Summary of each proposal. The duration of unsolicited proposal awards in CBET is generally up to three years. Single-investigator award budgets typically include support for one graduate student (or equivalent) and up to one month of PI time per year(awards for multiple investigator projects are typically larger). Proposal budgets that are much larger than typical should be discussed with the program director prior to submission. Proposers can view budget amounts and other information from recent awards made by this program via the ?What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)? link towards the bottom of this page. Faculty Early Career Development(CAREER)program proposals are strongly encouraged.Award duration is five years.The submission deadline for Engineering CAREER proposals is in July every year. Learn more in the CAREER program description. Proposals for Conferences, Workshops, and Supplements: PIs are strongly encouraged to discuss their requests with the program director before submission of the proposal. Grants forRapid Response Research(RAPID)andEArly-concept Grants for Exploratory Research(EAGER)are also considered when appropriate. Please note that proposals of these types must be discussed with the program director before submission. Grant Opportunities for Academic Liaison with Industry (GOALI)proposals that integrate fundamental research with translational results and are consistent with the application areas of interest to each program are also encouraged. Please note that RAPID, EAGER, and GOALI proposals can be submitted anytime during the year. Details about RAPID, EAGER, and GOALI are available in the Proposal & Award Policies & Procedures Guide(PAPPG), Part 1, Chapter II, Section E: Types of Proposals. Compliance: Proposals that are not compliant with theProposal & Award Policies & Procedures Guide (PAPPG)will be returned without review.
The Centers for Disease Control and Prevention's National Center for Injury Prevention and Control (NCIPC) is soliciting investigator-initiated research proposals to conduct a well-designed study within two or more assisted living facilities serving a diverse patient population to adapt, implement, and evaluate STEADI-based older adult (age 65+) fall prevention. Of particular interest is research that focuses on populations experiencing high rates of older adult falls and fall injuries within these assisted living facilities. These disproportionately affected populations could include: Tribal populations; rural populations; populations disadvantaged by reduced economic stability or limited education attainment; and populations with cognitive (e.g., dementia, Alzheimer’s disease), comorbidities, or physical limitations.
This Funding Opportunity Announcement (FOA) supports Small Business Technology Transfer (STTR) applications from small business concerns (SBCs) that propose the development of therapeutic agents for the treatment of alcohol use disorder (AUD) and/or alcohol associated organ damage (AAOD). As a starting point, eligible applicants must identify a therapeutic candidate with a robust body of background data in the basic science and early discovery phases to be ready for transition to the preclinical and clinical phases of development. Data may include having sufficient bioactivity, stability, manufacturability, bioavailability, in vivo efficacy and/or target engagement, and other favorable properties that are consistent with the desired clinical application. Projects responsive to this announcement could be undertaken at any point along the drug development continuum, from late discovery (i.e., lead optimization/early safety) up to early-stage clinical trials. For small molecules, the earliest stage of eligibility for this Award is already having small-molecule compounds with proof of desired pharmacological activity. For biologics, the profiling of promising product candidates in animal models of AUD or AAOD will be allowed as the earliest entry point. The ultimate purpose and goal of this FOA is to advance molecules closer to U.S. Food and Drug Administration (FDA) approval. Milestones will be commensurate with the project proposed and the purpose of this FOA. This FOA supports early-phase clinical trials, although these are not required. Women-owned and Small Disadvantaged small business are encouraged to apply.
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to provide the infrastructure for early-phase cancer prevention clinical trials through the Cancer Prevention Clinical Trials Network (CP-CTNet), DCP's main mechanism for early clinical development of cancer preventive interventions. The phase 0-2 trials performed through CP-CTNet evaluate biologic effects of interventions and determine clinically relevant correlates, with the ultimate goal of advancing their further development for cancer prevention. The research network will develop multiple cancer prevention clinical trials targeting cancers arising in various organ sites, including collaborative studies across the Network, using the UG1 cooperative agreement funding mechanisms. This NOFO relates to the performance sites that will plan and perform clinical trials.
The National Endowment for the Humanities (NEH) Division of Public Programs is accepting applications for the Public Humanities Projects program. This program supports projects that bring the ideas and insights of the humanities to life for general audiences through in-person, hybrid, or virtual programming. Projects must engage humanities scholarship to analyze significant themes in disciplines such as history, literature, ethics, and art history.
The Applied Mathematics program supports mathematics research motivated by or having an effect on problems arising in science and engineering. Mathematical merit and novelty, as well as breadth and quality of impact on applications, are important factors. Proposals to develop critical mathematical techniques from individual investigators as well as from interdisciplinary teams are encouraged. Proposals whose primary applications are in the biological sciences are inappropriate for Applied Mathematics, and should be submitted elsewhere; see the synopsis of the DMS Mathematical Biology program on that program's webpage for further guidance. Conferences Proposals to the Applied Mathematics program for conferences or workshops should be submitted through the program solicitation "Conferences and Workshops in the Mathematical Sciences" (link below). Principal Investigators should carefully read the program solicitation to obtain important information regarding the substance of proposals for conferences, workshops, summer/winter schools, and similar activities. To facilitate timely notification of the availability of support: Proposals for conferences, workshops, etc., to be held in the US must be submitted 8 months in advance of the conference date; Proposals to support group travel to meetings outside the US must be submitted 12 months in advance of the meeting date; Proposals for conferences, workshops, etc., whose budget request exceeds $50,000 must be submitted during the annual November 1-15 submission window.
This Funding Opportunity Announcement (FOA) uses a R61/R33 Phased Innovation Award mechanism to support clinical research applications that are exploratory and developmental in nature and focus on understanding the neurobiological mechanisms underlying SUD, including fundamental brain function relevant to substance use. This FOA is particularly designed to support exploratory/developmental projects requiring budgets that would exceed that allowed for the R21 mechanism (Neuroscience Research on Drug Abuse (R21 Clinical Trial Optional)
With this non-competitive solicitation, BJA seeks to request applications from 16 cooperative agreement recipients and one grantee that have been previously funded to support state, local, tribal, and territorial criminal justice agencies, courts, practitioners, and communities.
NSF invites supplemental requests for Small Business Innovation Research and Small Business Technology Transfer (SBIR/STTR) grantees to join an Industry/University Cooperative Research Center (I/UCRC). The supplements are intended to accelerate the innovation process by partnering industry-relevant academic research with commercialization focused small business research. The supplements will enable small businesses to purchase annual memberships in I/UCRCs; thus opening the doors to the benefits of the centers’ collaborative research endeavors, which are directed to the needs of specific industries. Please see the "Related URL" section for additional information about this opportunity.
The Centers of Biomedical Research Excellence (COBRE) program supports the establishment and development of innovative biomedical and behavioral research centers at Institutional Development Award (IDeA)-eligible institutions through awards for three sequential five-year phases. The purpose of the COBRE Phase 2 award is to strengthen successful COBRE Phase 1 centers established in Phase 1 through further improvements to research infrastructure and the continued development of a critical mass of investigators with shared scientific interests who are able to compete effectively for independent research funding and further improvements to research infrastructure at the institution.
The purpose of this research announcement is to support investigator-initiated research to rigorously evaluate policies and programs for the primary prevention of ACEs. In alignment with NCIPC’s ACEs Research Priorities, projects are expected to evaluate prevention approaches at the community- or societal-level that address social and health inequities that place some populations at greater risk for ACEs. Research conducted with these funds will rigorously evaluate existing primary prevention approaches (i.e., policies or programs that are already developed and implemented or ready for implementation in the community or population of interest) that have not yet undergone rigorous evaluation or are not currently undergoing a rigorous outcome evaluation. This research is intended to expand the evidence base for ACEs prevention in one or more of the following strategy areas identified in the CDC’s ACEs Prevention Resource for Action: Ensure A Strong Start for Children, Promote Social Norms That Protect Against Violence and Adversity, and Strengthen Economic Supports to Families.
The National Endowment for the Humanities (NEH) Office of Digital Humanities is accepting applications for the Digital Humanities Advancement Grants program. The program supports work that is innovative, experimental, and contributes to the critical infrastructure that underpins scholarly research, teaching, and public programming in the humanities.
Some projects initiated with SBIR or STTR funding require considerable financing beyond the SBIR/STTR Phase II award to achieve commercialization. The development of medical biotechnology products is often impeded by a significant funding gap (known as the Valley of Death) between the end of the SBIR/STTR Phase II award and the commercialization stage. The goal of this FOA is to assist applicants in pursuing the next appropriate milestone(s) necessary to advance a product/technology that requires Federal regulatory approval or to bring a complex research tool to market. This opportunity aims to facilitate the transition of previously funded SBIR and STTR Phase II projects to the commercialization stage by promoting partnerships between NINDS SBIR or STTR awardees and third-party investors and/or strategic partners in the Phase IIB competing renewal. Applicants are strongly encouraged to secure independent third-party funding throughout the Phase IIB project period.
This Funding Opportunity Announcement (FOA) encourages research on the biology of high confidence risk factors associated with complex brain disorders, with a focus on the intracellular, transcellular and circuit substrates of neural function. For the purposes of this FOA, the term complex can refer to a multifactorial contribution to risk (e.g., polygenic and/or environmental) and/or highly distributed functional features of the brain disorder. Studies may be either hypothesis-generating (unbiased discovery) or hypothesis-testing in design and may utilize in vivo, in situ or in vitro experimental paradigms, e.g., model organisms or human cell-based assays. While behavioral paradigms and outcome measures can be incorporated into the research design to facilitate the characterization of intracellular, transcellular and circuit mechanisms, these are neither required nor expected. Studies should not attempt to model disorders but instead should aim to elucidate the neurobiological impact of individual or combined risk factor(s), such as the affected molecular and cellular components and their relationships within defined biological process(es). This can include the fundamental biology of these factors, components and processes. The resulting paradigms, component pathways and biological processes should be disseminated with sufficient detail to enrich common and/or federated data resources (e.g., those contributing to the Gene Ontology, Synaptic Gene Ontology, FAIR Data Informatics) in order to bridge the gap between disease risk factors, biological mechanism and therapeutic target identification. The present announcement seeks R01 applications.
The purpose of the NCI Transition Career Development Award to Promote Diversity (K22) is to assist postdoctoral fellows or individuals in equivalent positions to transition to positions of assistant professor or equivalent and initiate a successful biomedical career as an independent research scientist
This FOA encourages grant applications for Animal and Biological Material Resource Centers. These Centers provide support for special colonies of laboratory animals, as well as other resources such as informatics tools, reagents, cultures (cells, tissues, and organs) and genetic stocks that serve the biomedical research community in a variety of research areas on a local, regional, and national basis. The goal of projects supported by this FOA is to provide research resources that facilitate optimization and enhancement of scientific rigor, transparency, and experimental reproducibility of biomedical research. Proposed Animal and Biological Material Resource Centers must have broad application to multiple NIH Institutes or Centers (ICs) to align with the ORIPs NIH-wide mission (https://orip.nih.gov/about-orip). This funding opportunity is designed to support both continuation of existing resources and to develop new ones when appropriate. Prior to preparing an application, all applicants are strongly encouraged to consult with Scientific/Research staff to be advised on appropriateness of the intended resource plans for this program, competitiveness of a potential application, and ORIP's program priorities.
The MSRP EHDA supports the initial exploration of innovative, high-risk, high-gain, and potentially groundbreaking concepts in the MS research field. The studies supported by this award mechanism are expected to lay the groundwork for future avenues of scientific investigation. The proposed research project should include a well-formulated, testable hypothesis based on strong scientific rationale and study design. The presentation of preliminary and/or published data is not required. The proposed research project must be innovative. Innovative research may examine a novel paradigm, challenge current paradigms, look at existing problems from novel perspectives, or exhibit other highly creative qualities. Research that is an incremental advance beyond ongoing research or published data is not considered innovative and is not consistent with the intent of this award mechanism. It is the responsibility of the Principal Investigator (PI) to clearly and explicitly articulate how the proposed research project is innovative in the field of MS research. For the “Correlates of Disease Activity and Progression in MS” Focus Area, applications must demonstrate access to the relevant specimens and/or data of the proposed cohort. Refer to Attachment 9: Letter(s) Confirming Access to Specimens and/or Data for more details. Note for projects involving animal models of MS: Applicants should be prudent in the choice of animal model(s) for their proposed research project. Applicants must justify the relevance of their proposed animal model(s) to the specific aspect of human MS to be studied. New Investigator option: The FY24 MSRP EHDA mechanism encourages applications from investigators in the early stages of their MS research career. The New Investigator option is designed to support the continued development of promising independent investigators that are early in their faculty appointments. Applications from Established Investigators and New Investigators will be peer- and programmatically reviewed in separate groups. PIs applying under the New Investigator option are encouraged to strengthen their applications through collaboration with investigators experienced in MS research and/or possess other relevant expertise as demonstrated by a record of funding and publications.
This funding opportunity announcement (FOA) seeks to support research that examines the impact of leveraging health information technology (health IT) to reduce health care disparities in access to care, patient-clinician communication, and health outcomes for populations that experience health disparities in the U.S.
The goal of this program is to detect, prevent, eradicate, and/or control invasive plant species to promote ecological resiliency, watershed stability, and biological diversity on Federal, State, other public or private lands in the Great Lakes Basin. | An informational webinar will be held on July 24th, 2024, at 10am Central/11 am Eastern. Connection information will be posted on the website and on this opportunity. Recording and transcript PowerPoint Presentation (PDF) | | The webinar recording is also posted on our website at https://www.fs.usda.gov/detail/r9/workingtogether/grants/?cid=FSEPRD898821. |
The purpose of this Funding Opportunity Announcement is to support research that investigates the effectiveness of school-based health centers (SBHCs) as a health services care delivery model to address the needs of school-aged children from populations with health disparities (underserved youth).
The purpose of the NIDCD Research Dissertation Fellowship for Au.D. Audiologists (F32) program is to support a comprehensive, rigorous biomedical research training, and dissertation research leading to a research doctorate (i.e., Ph.D.) in the biomedical, behavioral, or clinical sciences.
The specific purpose of this NOFO is to promote the development of a diverse, interdisciplinary workforce needed to conduct translational research on Alzheimer's disease and Alzheimer's-related dementias from target discovery through clinical development. This NOFO will support institutional training programs for predoctoral and postdoctoral level researchers with diverse educational backgrounds (i.e., basic biology, translational and clinical research, data science). The program invites eligible institutions to develop interdisciplinary training programs that will provide trainees with the knowledge and skills in data science, disease biology, behavioral research, and traditional and emerging drug discovery disciplines necessary to conduct rigorous and cutting-edge basic, translational, and clinical research for AD/ADRD.
The Bureau of lnternational Labor Affairs (ILAB), U.S. Department of Labor (DOL, or the Department), announces the availability of approximately $4,000,000 total costs (subject to the availability of Federal funds) for one cooperative agreement to fund a technical assistance project in the United Republic of Tanzania to improve implementation of laws, policies, and action plans to combat child labor (CL) and promote Acceptable Conditions of Work (ACW) in artisanal and small-scale gold mining (ASGM). We encourage prospective applicants and interested parties to use the Grants.gov subscription option to register for future updates provided for this particular FOA. | In order to achieve the project goal, applicants must propose strategies to achieve the following outcomes: | Outcome(s)(1) Increased capacity of key stakeholders to collect and disseminate data on CL and ACW in ASGM;(2) Increased monitoring, identification, and reporting of instances of CL and ACW in ASGM; and(3) Increased capacity of key stakeholders to address CL and promote ACW in ASGM at the local level. | Questions regarding this Funding Opportunity Announcement (FOA) Forecast may be emailed to [email protected].
This is a Notice of Intent to Issue Funding Opportunity Announcement No. DE-FOA-0003215, titled University Training and Research for Fossil Energy and Carbon Management. The University Training and Research (UTR) Program, sponsored by Office of Fossil Energy and Carbon Management (FECM) and administered by the National Energy Technology Laboratory (NETL), has the following primary mission objectives: 1) educate and train the next generation of engineers and scientists; 2) support novel, early-stage research at U.S. colleges and universities; 3) increase research and development opportunities for underrepresented and structurally marginalized communities; 4) ensure that students are being equipped with cutting-edge, translatable skillsets that will allow them to contribute to the U.S. workforce and greater economy over the course of a longstanding and enduring career. This NOI is for informational purposes only; the Department of Energy (DOE) is not seeking comments on the information contained in this notice. Applications are not accepted at this time. Any information contained in this notice is subject to change.
This Funding Opportunity Announcement (FOA), issued by the National Institute of Allergy and Infectious Diseases (NIAID), invites applications for investigator-initiated Resource-Related Research Projects (R24). The proposed resource must provide a significant benefit to currently funded high priority projects in need of further coordination and support in the areas specified. Under rare circumstances, this mechanism may be used to support development of a new resource to the broader scientific community of the NIAID. It is anticipated that the request for resource support through the R24 activity code will occur on an infrequent basis and only in circumstances where other mechanisms of support from the NIAID are not appropriate. The proposed resources should be relevant to the scientific areas of the NIAID mission including the biology, pathogenesis, and host response to microbes, including HIV; the mechanisms of normal immune function and immune dysfunction resulting in autoimmunity, immunodeficiency, allergy, asthma, and transplant rejection; and translational research to develop vaccines, therapeutics, and diagnostics to prevent and treat infectious, immune-mediated, and allergic diseases.
This Funding Opportunity Announcement (FOA) supports applications to develop and implement a Clinical Coordinating Center (CCC) for investigator-initiated multi-site clinical trials including efficacy, comparative effectiveness, pragmatic and/or implementation research clinical trials. Trials for which this FOA applies must be relevant to the research mission of the NHLBI and meet the NIH definition of a clinical trial (see NOT-OD-15-015). For additional information about the mission, strategic vision, and research priorities of the NHLBI, applicants are encouraged to consult the NHLBI website.This FOA will utilize a bi-phasic, milestone-driven cooperative agreement mechanism of award and runs in parallel with a companion FOA that encourages applications for a collaborating Data Coordinating Center (PAR-22-NNN). The objective of the CCC application is to present the scientific rationale for the clinical trial and a comprehensive scientific and operational plan that describes it. The application should address project management, subject recruitment and retention, performance milestones, scientific conduct of the trial, and dissemination of results. Both a CCC application and a collaborating Data Coordinating Center (DCC) application must be submitted on the same application due date for consideration by NHLBI. Applicants are strongly encouraged to contact the appropriate Scientific/Research contact prior to submitting an application.
GL to update purpose after the NOFO is finalized. Develop plans to establish or enhance BME departments, interdisciplinary technology centers, and/or academic programs which may include: Support research and educational opportunities for trainees in bioengineering and technology development (Undergrad and/or Graduate) Plans for core technology facilities, maker space, data science centers Faculty recruitment, collaborative research programs, training, and partnerships Building curriculum and course development Innovation and entrepreneurship programs Plans for sustainability of programs
The FY24 RCRP RCDA supports the development of clinical or preclinical data sets and research resources that advance the field of rare cancers research and ultimately improve outcomes for individuals with rare cancers. Major gaps in patient care of rare cancers include lack of communication and dissemination strategies for rare cancers research and clinical findings within communities; lack of therapeutics and mechanistic studies to inform treatment development; lack of research and clinical resources, including patient tissues, cell, and tumor models; and lack of infrastructure for sharing data and other resources.The intent of this funding opportunity is to develop research platforms that can share resources and knowledge pertaining to available preclinical or clinical research models, molecular pathways, and therapeutic approaches to facilitate collaboration and information sharing among stakeholders such as researchers, patients, caregivers, clinicians, and other members of the rare cancers community.Clinical or preclinical datasets should strive to integrate or develop the following research resources. This list is not all-inclusive:• Building and sharing rare tumor biospecimen repository with clinical annotation• Databases/banks for centralizing and sharing data for patient registries that can be accessed globally• Centralizing and sharing research models and molecular data related to genomics/ transcriptomics/immune profiling/proteomics/metabolomics/methylomics/bioinformatics• Generating a data/reagent/model exchange program where researchers can list resources that they are willing to share and are tagged with indications that may be relevant• Platform to enable or leverage longitudinal studies of disease natural history and treatment response• Development of novel methods and systems for collection, sharing, and analysis of data or biospecimensApplicants should include a well-formulated project design based on a strong scientific rationale and clearly articulate how the proposed resource platform or community development addresses an unmet need in rare cancers research. Applicants should explain the advantage of their approach to developing resources or community versus standard methodologies, techniques, or scopes. A clear plan for collaboration and data sharing needs to be demonstrated. It is critical to demonstrate how the outcome of the proposed project can benefit type(s) or sub-type(s) of rare cancers. It is encouraged for the research platform/resource to have an effect on multiple types or sub-types of rare cancers.Key Elements of the Resource and Community Development Award are as follows:• Impact: Outcomes of the RCDA must have potential for major impact on an unmet need in rare cancers research. A resource, as developed in the proposed research, should aim forDOD FY24 Rare Cancers Resource and Community Development Award 5long-term anticipated advantages toward greatly improving outcomes for people with rare cancers.• Patient Advocate Partnership: Applications to the RCDA funding opportunity are required to include patient advocates who are involved with patient advocacy organization(s). The research team must include at least two rare cancers patient advocates who will be early and integral partners throughout the planning and implementation of the research project. Patient advocates should be involved in the development of the research question, project design, oversight, and evaluation, as well as other significant aspects of the proposed project. Interactions with other team members should be well integrated and ongoing, and not limited to attending seminars and semi-annual meetings. The patient advocates must be individuals who have been directly impacted by a rare cancer either by being diagnosed themselves or as a caretaker/family member of a patient, and they should be active in a cancer advocacy organization or within a support group focused on their rare cancer. Their role should be focused on providing objective input on the research and its potential impact for individuals with or at risk for a rare cancer. The patient advocates should have a high level of understanding of current rare cancers research.• Preliminary Data: Due to the developmental nature of this award, preliminary data are not required but may be included, if available, to address the feasibility of the resource to be developed. Whether or not preliminary data are included, applications must apply solid scientific rationale and logical reasoning based on existing knowledge to the development of the proposed product.• Clinical Research: Research involving human subject use is permitted under this mechanism but is restricted to studies without clinical trials. Clinical trials will not be supported. Applications focused on clinical research should demonstrate how the study will leverage clinical information to address knowledge gaps in the development of platforms that can be utilized for sharing data and tissue, the development of clinical annotation datasets, process development, and/or infrastructure development.• Applied Research: Preclinical studies utilizing or creating animal models to further research into rare cancers may be supported by this funding opportunity. The RCDA is intended to support projects that will have the potential to move beyond the realm of basic research, with results that may impact clinical research or patient outcomes.• Community Building: A plan describing how the rare cancers stakeholder community will be built/enhanced and the community’s involvement with developing the resource platform is required. It is also important to justify how the community is essential for the development and sustainment of the resource platform.• Dissemination: A Dissemination Plan is required. The plan should describe the means by which the fully developed resource platform will be made easily available to the scientific and/or clinical community. Dissemination of resource platform will play a major role by not only educating the rare cancer community about the recent progress, but also help to develop an informational network.DOD FY24 Rare Cancers Resource and Community Development Award 6• Sustainment: A plan that outlines the sustainability of the resource in the future is required. The plan should detail the types of rare cancers that are less studied in the collaborations and the resources to be gathered, annotated, and sustained. Additional expansion and feasibility plans should be included. It is important to demonstrate how the outcomes of the current award will be continued and eventually will help the rare care cancer community, beyond the award period.A congressionally mandated Metastatic Cancer Task Force was formed with the purpose of identifying ways to help accelerate clinical and translational research aimed at extending the lives of advanced state and recurrent patients. As a member of the Metastatic Cancer Task Force, CDMRP encourages applicants to review the recommendations (https://health.mil/Reference-Center/Congressional-Testimonies/2018/05/03/Metastatic-Cancer-Research) and submit research ideas to address these recommendations provided they are within the limitations of this funding opportunity and fit within the FY24 RCRP priorities.Collaborations between researchers at military or Veteran institutions and non-military institutions are strongly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the partners bring to the research effort, ultimately advancing cancer research that is of significance to the Warfighter, military Families, and the American public.Innovative research involving nuclear medicine and related techniques to support early diagnosis, more effective treatment, and improved health outcomes of active-duty Service Members and their Families is encouraged. Such research could improve diagnostic and targeted treatment capabilities through noninvasive techniques and may drive the development of precision imaging and advanced targeted therapies.CDMRP encourages research on health areas and conditions that affect women uniquely, disproportionately, or differently from men, including studies analyzing sex as a biological variable. Such research should relate anticipated project findings to improvements in women’s health outcomes and/or advancing knowledge for women's health.All projects should adhere to a core set of standards for rigorous study design and reporting to maximize the reproducibility and translational potential of clinical and preclinical research. The standards are described in SC Landis et al., 2012, A call for transparent reporting to optimize the predictive value of preclinical research, Nature 490:187-191 (https://www.nature.com/nature/journal/v490/n7419/full/nature11556.html). While these standards are written for preclinical studies, the basic principles of randomization, blinding, sample-size estimation, and data handling derive from well-established best practices in clinical studies.
The Mathematical Biology Program supports research in areas of applied and computational mathematics with relevance to the biological sciences. Successful proposals must demonstrate mathematical innovation, biological relevance and significance, and strong integration between mathematics and biology. Some projects of interest to the Mathematical Biology Program may include development of mathematical concepts and tools traditionally seen in other disciplinary programs within the Division of Mathematical Sciences, e.g., topology, probability, statistics, computational mathematics, etc. In general, if a proposal is appropriate for review by more than one NSF program, it is advisable to contact the program officers handling each program to determine when and where the proposal should be submitted and to facilitate the review process. The Mathematical Biology Program regularly seeks joint reviews of proposals with programs in the Directorates of Biological Sciences and Engineering. Investigators are encouraged to discuss their project with program officers in relevant areas to determine if it should be considered by more than one program. Research in Undergraduate Institutions (RUI) Investigators submitting an RUI proposal should read the RUI solicitation (link below), as the rules for proposal format may deviate from the Proposal & Award Policies & Procedures Guide (PAPPG). EAGER and RAPID Proposals Prior to submitting proposals for EArly-concept Grants for Exploratory Research (EAGER) or Rapid Response Research (RAPID), Investigators must contact the cognizant program directors. Requests for Award Supplements Principal Investigatorsare encouraged to contact the cognizant program director prior to submission of a proposal for an award supplement. See the PAPPG for more information. Conferences Investigators should carefully read the program solicitation, "Conferences and Workshops in the Mathematical Sciences," (link below) to obtain important information regarding the substance of proposals for conferences, workshops, summer/winter schools, and similar activities. To facilitate timely notification of the availability of support: proposals for conferences, workshops, etc., to be held in the US must be submitted 8 months in advance of the conference date; proposals to support group travel to meetings outside the US must be submitted 12 months in advance of the meeting date.
The U.S. Department of State Bureau of Economic and Business Affairs (EB) announces an open competition for organizations to submit a statement of interest (SOI) to carry out a program under the International Technology Security and Innovation (ITSI) Fund, created by the CHIPS Act of 2022. Please carefully follow all instructions below. | The submission of the SOI is the first step in a two-step process. Applicants must first submit a concise no more than three (3) page statement of interest designed to clearly communicate the program idea and objectives. This is not a full proposal. The purpose of the SOI process is to allow applicants to submit program ideas for evaluation prior to requiring the development of a full proposal application. Upon a merit review of eligible SOIs, selected applicants will be invited to expand on their program idea(s) by submitting a full proposal application. Full proposals will go through a second merit review before final funding decisions are made. | EB administers a portion of the ITSI Fund, the “ITSI Promote” line of effort, to help expand international semiconductor assembly, testing, and packaging (“ATP” or “downstream”) capacity in key partner countries that will in turn diversify the global semiconductor supply chain. EB’s objectives under the ITSI Fund are to: 1) Expand and diversify the required workforce for semiconductor ATP facilities to ensure growth; and 2) Improve regulatory environments that will encourage private sector efforts that generate additional capabilities in ATP facilities. | This solicitation is specific to Mexico and includes three (3) categories under which applicants may submit SOIs: 1) Workforce Development, 2) Policy and Regulatory Reform, and 3) Supply Chain Development. See "Related Documents" tab for attached RSOI background, illustrative activities, and submission instructions. | If you have any questions about the SOI application process, please contact [email protected] by August 2, 2024. Emails must reference the funding opportunity number DFOP0016767 in the subject line. FAQ will be posted on Grants.gov by August 10, 2024. SOIs may be submitted via email to [email protected].
The purpose of the NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01) is to support comprehensive and rigorous postdoctoral research and career development experiences in the biomedical, behavioral, or clinical sciences of promising Au.D./Ph.D. audiologists who have the potential to become productive, independent investigators in scientific health-related research fields relevant to NIDCD's mission.
The purpose of the NIH Mentored Patient-Oriented Research Career Development Award (K23) is to support the career development of individuals with a clinical doctoral degree who have made a commitment to focus their research endeavors on patient-oriented research.
The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that encourage individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to pursue further studies or careers in research To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on:Courses for Skills DevelopmentResearch Experiences
The purpose of the Native American Research Centers for Health (NARCH) Planning Grants program is to support federally recognized American Indian/Alaska Native (AI/AN) Tribes, Tribal colleges and universities, Tribal health programs, or Tribal organizations (collectively, eligible AI/AN Tribal entities) to plan and conduct preparatory work for developing competitive NARCH applications.
This funding opportunity requires a Letter of Intent (LOI) to be submitted to [email protected] for competitive review before a full proposal can be submitted. LOIs must be submitted no later than 11:59 p.m. Eastern time, September 27, 2024. If invited, full proposals must then be submitted in Grants.gov (http://www.grants.gov) and validated by eRA on or before 11:59 p.m. Eastern time, January 31, 2025. The NOAA Marine Debris Program (MDP) is a division of the NOAA Office of Response and Restoration. Authorized in the Marine Debris Act, codified at 33 U.S.C. § 1951 et seq., the NOAA MDP supports the development and implementation of marine debris assessment, removal, and prevention projects that benefit coastal habitat, waterways, and marine and Great Lake resources. Marine debris is defined as "any persistent solid material that is manufactured or processed and directly or indirectly, intentionally or unintentionally, disposed of or abandoned into the marine environment or the Great Lakes" (15 C.F.R. § 909.1). The mission of the NOAA MDP is to investigate and prevent the adverse impacts of marine debris. Through this solicitation, NOAA seeks to support large marine debris removal projects with funding available through the Bipartisan Infrastructure Law (PL 117-58). The overall objective of this funding opportunity is to support impactful, large marine debris removal projects that will improve the resilience of the coastal and marine environment. This competition considers impactful projects to be those that will have long-lasting, transformational benefits to marine and coastal NOAA Trust Resources, coastal communities, and/or local economies. The Notice of Funding Opportunity (NOFO) describes the types of projects that are eligible for funding, as well as the proposal requirements and how applications will be evaluated. NOAA anticipates up to $47,000,000 will be available for this grant solicitation. The minimum federal request for this solicitation is $1,000,000. The maximum federal request is $10,000,000. The typical funding request will range from $2,000,000 to $6,000,000. Proposals requesting over $6,000,000 are expected to be proposals including a subaward competition for other organizations to identify and apply for funding for localized removal activities. Proposals requesting over $6,000,000 solely identifying marine debris targets for direct removal organized by the applicant should provide a detailed justification for why this amount of funding is needed. The exact amount of funds to be awarded and the number of awards made will be at the discretion of NOAA following pre-award negotiations with highly meritorious applicants.
The purpose of this individual postdoctoral research training fellowship is to enhance the research training of promising postdoctoral candidates who have the potential to become productive, independent investigators in health services research, with a research interest in areas and priorities relevant to the mission of AHRQ. This Notice of Funding Opportunity (NOFO) does not allow applicants to propose to lead an independent clinical trial but does allow applicants to propose research experience in a clinical trial led by a sponsor or co-sponsor.
The National Endowment for the Humanities (NEH) Division of Research Programs is accepting applications for the Summer Stipends program. The purpose of this program is to stimulate new research and publication in the humanities. Summer Stipends support continuous, full-time work on a humanities project for a period of two consecutive months. NEH funds may support recipients’ compensation, travel, and other costs related to the proposed scholarly research.
The purpose of this Funding Opportunity Announcement (FOA) is to invite applications proposing the innovative analysis of existing social science, behavioral, administrative, and neuroimaging data to study the etiology and epidemiology of drug using behaviors (defined as alcohol, tobacco, prescription and other drug) and related disorders, prevention of drug use and HIV, and health service utilization. This FOA encourages the analyses of public use and other extant community-based or clinical datasets to their full potential in order to increase our knowledge of etiology, trajectories of drug using behaviors and their consequences including morbidity and mortality, risk and resilience in the development of psychopathology, strategies to guide the development, testing, implementation, and delivery of high quality, effective and efficient services for the prevention and treatment of drug abuse and HIV.
This FOA will support integrated, interdisciplinary research teams that focus on examining dynamic circuit functions related to behavior, using advanced and innovative technologies. The FOA will support programs with a necessarily-synergistic, team science approach. Awards will be made for 5 years, with a possibility of one competing renewal. Applications should incorporate overarching principles of circuit function in the context of specific neural systems underlying sensation, perception, emotion, motivation, cognition, decision-making, motor control, communication, or homeostasis. Applications should incorporate theory-/model-driven experimental design and should offer predictive models as deliverables. Applications should seek to understand circuits of the central nervous system by systematically controlling stimuli and/or behavior while actively recording and/or manipulating relevant dynamic patterns of neural activity and by measuring the resulting behaviors and/or perceptions. Applications are expected to employ approaches guided by specified theoretical constructs, and are encouraged to employ quantitative, mechanistic models where appropriate. Applications will be required to manage their data and analysis methods in a framework that will be developed and used in the proposed U19 project and exchanged with other BRAIN U19 awardees for further refinement and development. Model systems, including the possibility of multiple species ranging from invertebrates to humans, can be employed and should be appropriately justified. Programs should employ multi-component teams of research expertise including neurobiologists, statisticians, physicists, mathematicians, engineers, computer scientists, and data scientists, as appropriate - that seek to cross boundaries of interdisciplinary collaboration. Applicants proposing to include human subjects with invasive neural recording must apply to the companion FOA, RFA-NS-XX-XXX.
The Bureau of International Labor Affairs (ILAB), U.S. Department of Labor (DOL, or the Department) announces the availability of approximately $3,000.000 total costs (subject to the availability of Federal funds) for one cooperative agreement to fund a technical assistance project in Cambodia to increase the responsiveness of Cambodian Organizations of Persons with Disabilities and their key stakeholders to labor exploitation and barriers that impede access to decent work. We encourage prospective applicants and interested parties to use the Grants.gov subscription option to register for future updates provided for this particular FOA. In order to achieve the project goal, applicants must propose strategies to achieve the following outcomes:Outcome(s)• (1) Increased understanding of the linkage between disability and vulnerability to child labor, forced labor and/or human trafficking and of barriers that impede access to decent work for persons with disabilities. • (2) Increased coordination and partnerships between/among Organizations of Persons with Disabilities (OPDs) and their key stakeholders to address the prevalence of child labor, forced labor and/or human trafficking among persons with disabilities and barriers that impede their access to decent work. • (3) Increased implementation of sustainable interventions by OPDs and their key stakeholders that address the linkage between disability and vulnerability to child labor, forced labor and/or human trafficking and barriers that impede access to decent work. | Questions regarding this Funding Opportunity Announcement (FOA) may be emailed to [email protected].
The purpose of this Notice of Funding Opportunity (NOFO) is to provide continuing support for specific pathogen-free (SPF) macaque colonies previously funded under the auspices of PAR-21-089 and PAR-18-669 that support Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) research. Breeding colonies are essential to sustain appropriate SPF macaques for research related to HIV/AIDS. Pedigree SPF macaques are free of certain viruses, which may confound the results of HIV/AIDS-related investigations or present a risk to the personnel who care for the animals. The SPF macaques are genetically characterized for major histocompatibility complex (MHC) class I types, because MHC class I genotypes have large effects on macaque immune responses to Simian Immunodeficiency Virus (SIV) that can induce AIDS in nonhuman primates (NHPs) and on human immune responses to HIV.
The goal of this Funding Opportunity Announcement (FOA) is to encourage applications for studies that will enhance knowledge of mechanisms associated with neuropsychiatric symptoms (NPS) in persons with Alzheimer's disease (AD) or Alzheimer's disease-related dementias (ADRD). The findings are expected to advance mechanistic understanding of both biobehavioral and neurobiological pathways leading to NPS. Findings may also provide insight into novel therapeutic targets that can be advanced into interventions to treat and prevent the development of NPS in AD and/or ADRD
Historic battlefields and associated sites of armed conflict are powerful reminders of the shared heritage of all Americans. In an ongoing effort to extend the conservation of natural and cultural resources beyond our park boundaries, the National Park Service American Battlefield Protection Program (NPS ABPP) promotes the preservation and interpretation of these important places. NPS ABPP supports community-driven stewardship of historic resources through four grant opportunities: Preservation Planning, Battlefield Restoration, Battlefield Interpretation, and Battlefield Land Acquisition.NPS ABPP administers Battlefield Land Acquisition Grants (BLAG) to assist State and local governments with the preservation of eligible Revolutionary War, War of 1812, and Civil War battlefield lands through acquisition of fee-simple or less-than-fee (easement) interests. Funding for the BLAG program is made available from the Land and Water Conservation Fund (LWCF) and is awarded competitively. Each grant requires a dollar-for-dollar non-Federal match. Grants are available to acquire interests in eligible Civil War battlefields listed in the Civil War sites Advisory Commission's (CWSAC) Report on the Nation's Civil War Battlefields (1993) and in the principal battlefields of the Revolutionary War and War of 1812 identified in NPS ABPP’s Report to Congress on the Historic Preservation of Revolutionary War and War of 1812 Sites in the United States (2007) (Survey Reports).A nonprofit organization may acquire an interest in an eligible site with a BLAG award in partnership with a State or local government.
The purpose of this Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutionsis to support small scale research grants at institutions that do not receive substantial funding from the NIH, with an emphasis on providing biomedical research experiences primarily for undergraduate students, and enhancing the research environment at applicant institutions. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million dollars per year of NIH support (in both direct and F and A/indirect costs) in 4 of the last 7 fiscal years. For institutions composed of multiple schools and colleges, the $6 million funding limit is based on the amount of NIH funding received by all the non-health professional schools and colleges within the institution as a whole. See Part II. Section 3.1 Eligible Organizations for more information.
This Funding Opportunity Announcement (FOA) encourages pilot and preliminary research in preparation for larger-scale services research effectiveness trials. Relevant trials may test a wide range of approaches, including interventions, practices, and policies designed to optimize access to, and the quality, effectiveness, affordability and utilization of drug, tobacco, or alcohol use disorder treatments and related services, as well as services for comorbid medical and mental disorder conditions. Relevant approaches may include both those that are novel, and those that are commonly used in practice but lack an evidence base. This FOA provides resources for assessing the feasibility, acceptability, and utility of these approaches, in addition to usual trial preparation activities.
This notice identifies the objectives for Community Food Projects Competitive Grant Program (CFPCGP) projects, deadlines, funding information, eligibility criteria for projects and applicants, and application forms and associated instructions. In FY 2024 NIFA’s CFPCGP intends to solicit applications and fund two types of grants. The grant types are (1) Planning Projects (PP) and (2) Community Food Projects (CFP).
The National Endowment for the Humanities (NEH) Office of Challenge Programs is accepting applications for the Climate Smart Humanities Organizations program. This program strengthens the institutional base of the humanities by funding operational assessments and strategic planning efforts to sustain and protect historical, cultural, educational, intellectual, and physical assets from the risks of climate change. Projects will result in a climate action, resilience, or adaptation plan including detailed assessments, measurable actions, and expected outcomes. Proposals must address how strategic planning for climate change will increase the organization’s resilience and support its work in the humanities over the long term. Projects are financed through a combination of federal matching funds and gifts raised from third-party, non-federal sources.
The purpose of this funding opportunity announcement (FOA) is to support preclinical HIV/AIDS research using NHP models performed by Early Stage Investigators (ESIs) who are within 10 years of their terminal degree or completion of their residency training but who have at least two years of postdoctoral experience. The goal of this support is to help advance HIV/AIDS researchers using NHP models in preclinical research by providing a degree of independence for these ESIs to develop new research directions and to position these researchers to be competitive for new research funding (e.g., R01). Proposed projects must use NHPs as preclinical models for HIV/AIDS research This funding initiative encompasses all priorities of the fiscal year (FY) 2021-2025 NIH Strategic Plan for HIV and HIV-Related Research (https://www.oar.nih.gov/hiv-policy-and-research/strategic-plan): reduce the incidence of HIV; develop next-generation HIV therapies; conduct research toward HIV cure; address HIV-associated comorbidities, coinfections, and complications; and advance cross-cutting areas of research.
The goal of this NOFO is to support R21 applications for novel theory and methods development that better delineate how genetic and non-genetic factors contribute to complex trait variation across individuals, families, and populations. Approaches should be interdisciplinary across the natural and social sciences, account for interdependencies across scales of biological, social, and ecological organization, and make extensive use of theory, simulations, and validation using available large-scale datasets
The United States Government, represented by the United States Agency for International Development (USAID), anticipates issuing a request for applications (RFA), late-March to early April 2012, inviting applications for a Cooperative Agreement to implement the Palestinian Community Infrastructure Development Program to increase Palestinians access to community infrastructure and provide rapid response to address urgent needs in the West Bank and Gaza. To reach this overall objective, the program will replace or upgrade water and sanitation networks in order to increase access to water resources and alleviate water losses; upgrade health facilities to improve essential health services; build and upgrade schools to provide improved learning facilities; and, provide other public infrastructure within and between communities to improve basic services and increase economic opportunities. Subject to the availability of funds, this competitively awarded five year Cooperative Agreement shall focus on implementing projects primarily in rural and vulnerable communities that face serious shortages in basic services. USAID will advise applicants of project objectives and desired outcome; however, applicants must provide the methodology or approach for implementation of the project. Applicants will have the opportunity to propose a sound, cost effective approach for the Program. This will be a competitive announcement, and USAID encourages all U.S. non-governmental organizations to consider this opportunity.
With this solicitation, NIJ seeks proposals from qualified applicants to establish and operate a Forensic Technology Center of Excellence (FTCOE) to support NIJ’s research, development, testing, and evaluation (RDT&E) process and technology transition activities in all areas of forensic science.
To support research project for validation of organ-on-a-chip (OoC) toward disease modelling and pre-clinical efficacy studies in dental, oral, and craniofacial (DOC) research.
The 21st Century Conservation Service Corps and Civilian Climate Corps ProgramsOverview: NPS Youth and Veteran Development Programs represent the future of the NPS and encompasses a full range of 21CSC/CCC oriented developmental programs and projects conducted in and around national park units, NPS support offices, as well as in local communities and with partner organizations. NPS Youth Development Programs are committed to evolving and advancing vibrant and relevant youth and young adult programming that emphasize the mission of the NPS. NPS Youth Development Programs are designed to provide employment, education, experiential learning, and public service opportunities to U.S. citizens and legal residents who are between the ages of 16 and 30, and veterans up to 35 years of age.The 21CSC/CCC is a collaborative effort between federal government agencies and non-profit service organizations to put America’s youth and veterans to work protecting, restoring and enhancing America’s great outdoors. Through the 21CSC/CCC, young people and veterans will accomplish meaningful work, and gain important personal and professional skills while building a lifelong connection to the outdoors. The 21CSC/CCC strives to achieve the following public purpose goals and objectives:1) Put Americans to Work: The 21CSC/CCC will provide service, training, education and employment opportunities for thousands of young Americans and veterans, including low income and disadvantaged youth.2) Preserve, Protect, and Promote America's Greatest Gifts: The 21CSC/CCC will protect, restore, and enhance public and tribal lands and waters as well as natural, cultural, and historical resources and treasures. By producing high-quality, cost-effective project work from the 21CSC/CCC will also increase public access and use while spurring economic development and outdoor recreation.3) Build America's Future: Through service to the United States of America, the 21CSC/CCC will help develop a generation of skilled workers, educated and active citizens, future leaders, and stewards of natural and cultural resources, communities, and the nation.4) Provide a Living Wage: A reasonable living wage which is at the minimum equivalent to the minimum wage for the area. A continuum of benefits to support a corps members whole person can include compensation, housing, and other benefits.5) Provide a Pathway to Employment: Build a pipeline of talent and skilled labor of individuals inspired to enter public service or set them up for good-paying careers through intentional labor partnerships, pre-apprenticeship programs, and more.6) Represent America: Corps members should reflect the rich diversity of America, including hiring people from underserved communities, individuals with disabilities, Native Tribes, returning veterans, and unskilled young adults seeking vocational, internship, and educational opportunities.7) Tackle Climate Change: Tackle climate change from all angles by expanding the scope of climate solutions projects eligible for federal government support.8) Appropriate conservation projects and other appropriate projects to be carried out on federal, state, local, or private land as part of a federal disaster prevention or relief effort.Purpose: The NPS Youth Development Programs Division seeks to develop collaborative partnerships with non-profit youth-serving organizations who have the expertise to develop and administrator 21CSC programs that focus on providing employment, education, and engagement opportunities for U.S. citizens and legal residents in NPS units and affiliated sites such as National Register of Historic Places, National Heritage Areas, National Wild and Scenic Rivers, National Historic Landmarks, National Trails, and adjacent gateway communities. The primary purpose of the funds is for the benefit of the interns participating in the program.Participant Requirements: U.S. citizens and legal residents between the ages of 16 and 30 years of age, and veterans up to 35 years of age.Types of Projects: Natural and cultural resource conservation projects that are developed in collaboration with NPS officials with an emphasis on public purpose for the benefit of the American public, as well as, for providing employment and educational opportunities to young people and veterans. These projects will provide the participants with job skills training, education, and/or professional development. The employment focused projects are organized in either: 1) a crew-based format where the participants work collectively and intensely together and are directly supervised by trained and experienced crew leaders or conservation professionals; or 2) a individual or small team-based format where participants work individually or in coordinated teams under the direction of conservation professionals on initiatives that require specific skills and dedicated attention. The work projects include significant outdoor activity and/or helps young people and veterans connect with “America’s Great Outdoors”. Some projects may include work primarily indoors (i.e., research, policy, web development, visitor services, or administration) but also has a clear and direct connection to natural and cultural resource conservation.Project Examples:Climate change mitigation and resilienceCyclic maintenanceDevelopment of educational resource materials for visitorsEcosystem restorationEnhancing recreational opportunitiesField-based service such as trail building/restoration, removing invasive species and habitat restoration.GIS and mapping resourcesInterpretation of natural and cultural resourcesMuseum curationPreserving historic structuresProtecting of wildlife and preserving lands and structuresResearch such as scientific, historic, archival, archaeological digs, oral histories, historic preservation, and habitat surveys etc.Restoration and rehabilitation of facilitiesSupport management of natural and cultural resources such as developing and implementing resource stewardship plans, developing educational and informational materials for park visitorsTechnologically based natural and cultural resource educational programs and communication outreachVisitor educationEducation Projects: The National Park Service is committed to providing educational opportunities to 21CSC qualified individuals that help them to learn about American values, civic engagement, and citizenship stewardship. These projects utilize various educational techniques to convey and teach the NPS mission of natural and resource conservation.Education Project Examples:Projects that target 21CSC qualified participants and provide place-based learning opportunities with a focus on natural and/or cultural resource stewardship.Seminars that provide training opportunities for 21CSC qualified participants that promote natural and cultural resource stewardship and gateway community collaboration.Applicant Organizational RequirementsThe applicant organization should be able to clearly demonstrate their ability to design natural and cultural resource conservation projects that accomplish needed and important work on public lands while at the same time providing their 21CSC participants with educational, technical, life, and leadership skills. Each participant should develop a sense of community and purpose from their work on these projects. NPS may give preference to qualified youth or conservation corps organizations (see definition below) located in a specific area that have a substantial portion of members who are economically, physically, or educationally disadvantaged to carry out projects within the area. Park asset acquisition or personal services are not allowable.Public Land Corps Law DefinitionQualified Youth or Conservation Corps means any program established and administered by a State or local government, by the governing body of any Indian tribe, or a nonprofit organization that: 1) Carries out appropriate conservation projects on or related to eligible service land; 2) Is capable of offering meaningful, full-time, productive work for individuals between the ages of 16 and 30, inclusive, or veterans age 35 or younger, in a natural or cultural resource setting; 3) Engages participants in a variety of work experience, basic and life skills, education, training, and support services; 4) Provides participants with the opportunity to develop citizenship values and skills through service to their community and the United States; and 5) Provides the individual with a living allowance, stipend, or wages.
Under 25 USC §2020 funds will support the program goals for the following areas that promote tribal education capacity building:To provide for the development and enforcement of tribal educational codes, including tribal educational policies and tribal standards applicable to curriculum, personnel, students, facilities, and support programs;To facilitate tribal control in all matters relating to the education of Indian children on reservations (and on former Indian reservations in Oklahoma);To provide for the development of coordinated educational programs (including all preschool, elementary, secondary, and higher or vocational educational programs funded by tribal, Federal, or other sources) on reservations (and on former Indian reservations in Oklahoma) by encouraging tribal administrative support of all Bureau-funded educational programs as well as encouraging tribal cooperation and coordination with entities carrying out all educational programs receiving financial support from other Federal agencies, State agencies, or private entities.
This Notice of Funding Opportunity (NOFO) invites applications to form an interdisciplinary network of scholars from a variety of disciplines to collaborate with each other in the measurement and modeling of structural racism to facilitate research on life course health and aging.
The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project that represents a change in research direction for an early stage investigator (ESI) and for which no preliminary data exist. Applications submitted to this Notice of Funding Opportunity Announcement (NOFO) must not include preliminary data. Applications must include a separate attachment describing the change in research direction. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions. This Funding Opportunity is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this NOFO include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Studies that are NOT conducted with specific applications toward processes or products in mind and which also do not meet the clinical trial definition should submit under the appropriate Clinical Trial Not Allowed NOFO .
ATTENTION: This announcement will be revised regularly to incorporate country specific narratives (Attachment 1 of the announcement) with information vital to the content of application. Potential applicants interested in applying to this announcement should click 'Subscribe' to be notified of future revisions. DoD HIV/AID Prevention Program's (DHAPP) objective, through the PEPFAR program, is to save lives, prevent HIV infections, and accelerate progress toward achieving HIV/AIDS epidemic control and to support the development of interventions and programs in military health systems that address these issues. DHAPP works with militaries of foreign countries to devise plans based on the following process:Meet with key partners in country to determine provisional major program areas and other technical assistance needs.Adapt DHAPP support to a country’s need for prevention, care and/or treatment of its HIV/AIDS situation based on an assessment of the country’s epidemic, and more specifically, in that country’s military.Strengthen the military capacity for ownership and behavioral changes over the long term.Consider program design by leveraging assets with other country partners who have/had successful prevention, care, and/or treatment efforts.Focus on prevention, care and/or treatment impact aligned with national implementation plans.Implement and monitor programs to ensure accountability and sustainability. | Countries and their militaries need strong evidenced based HIV programs with measurable courses of action that demonstrate the following specific attributes. Priorities for DHAPP include the following but are subject to change.Support and ownership from the military sector.Development of plans of action and support for military policies that further HIV epidemic control.Alignment with PEPFAR and national strategies and priorities.Testing and treatment expansion to meet 2020 goals of 90-90-90 and 2030 goals of 95-95-95 for people living with HIV. (The first goal is identifying 90/95 percent of all HIV-positive individuals in the population; the second goal is linking 90/95 percent of all those identified HIV positive people to consistent antiretroviral treatment; and the last goal is reaching 90/95 percent of all those on antiretroviral treatment to attain viral suppression.)Care and treatment plans should use the “Treat All” approach with differentiated models of care including tuberculosis (TB), hepatitis, cervical cancer in HIV positive women, other sexually transmitted infections (STI) other opportunistic infections, and care for those with advanced HIV disease.Reduction of mother-to-child transmission of HIV.Combination prevention using biomedical, behavioral and structural support for sexual transmission of HIV and other STI.Prevention packages for specific populations including a comprehensive package for Key Populations (KP), Priority Populations, and prevention interventions for young people.Stigma and discrimination reduction associated with HIV infection.Program monitoring to collect and report on PEPFAR indicators, ensure quality of service delivery using clinical and laboratory monitoring tools and to take rapid corrective action based on results.Strengthen HIV data collection systems for improved clinical decision making and program management.Promoting sustainability through capacity building of the military partner.Transition to Local Partners: Local partners are encouraged to apply to this announcement. | To sustain epidemic control, it is critical that the full range of HIV prevention and treatment services are owned and operated by local institutions, governments, and community-based and community-led organizations – regardless of current antiretroviral (ARV) coverage levels. The intent of the transitioning to local partners is to increase the delivery of direct HIV services, along with non-direct services provided at the site, and establish sufficient capacity, capability, and durability of these local partners to ensure successful, long-term, local partner engagement and impact.
The U.S. Embassy Bridgetown Public Affairs Section of the U.S. Department of State is pleased to announce that funding is available through its Public Diplomacy Small Grants Program. This is an Annual Program Statement. Please see attached Annual Program Statement for full details.
This funding opportunity announcement (FOA) encourages applications from small business concerns (SBCs) for Small Business Innovation Research (SBIR) projects to develop novel tools and devices to improve handling of laboratory animals, to ease the management of animal facilities, and to enhance experiments which use animal models. The intent is to facilitate the design, implementation, and creation of tools and devices to directly benefit the welfare of research animals, and to advance equipment to improve infrastructure and environmental conditions of animal facilities that support biomedical and bio-behavioral research.
The purpose of this FOA is to enhance the capability of NCATS CTSA Program KL2 scholars and recipients of diversity and re-entry supplements supported by the CTSA Program to conduct research as they complete the transition to fully independent academic translational scientists. These R03 grants will support different clinical and translational science research projects, including pilot and feasibility studies; secondary data analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. Research proposed in the R03 application may or may not include patient-oriented research. The R03 is, therefore, intended to support research projects that can be carried out in a short period of time with limited resources and that provide preliminary data to support submission of a subsequent R01, or equivalent, application.
The purpose of this Funding Opportunity Announcement (FOA) is to stimulate HIV/AIDS research within the scientific mission areas of the National Institute on Deafness and Other Communications Disorders (NIDCD). Applications should address high priority HIV/AIDS research outlined by the NIH Office of AIDS Research (OAR) [https://www.oar.nih.gov/hiv-policy-and-research/research-priorities] in the areas of hearing, balance, taste, smell, voice, speech, or language. For applicationswith a clinical trial, only low risk clinical trials will be supported.
The purpose of the Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) program is to fund federally recognized American Indian/Alaska Native (AI/AN) Tribes, tribal colleges or universities, Tribal health programs, or Tribal organizations (collectively termed, eligible Tribal Entities) to identify and develop a pool of scientists to conduct research on AI/AN health and health disparities. Through this Notice of Funding Opportunity (NOFO), NIGMS will provide support for a phased award to eligible AI/AN Tribal Entities to develop (UE5) and implement (T32) effective training and mentoring activities for research-oriented individuals earning a doctoral degree in a biomedical research field at a variety of institutions across the United States and territories. The overall purpose is to support the development of individuals who have the technical, operational, and professional skills required to conduct AI/AN health research in a culturally appropriate, ethically responsible and rigorous manner, to complete Ph.D.s in a biomedical field, and to transition into careers in the biomedical research workforce.
The purpose of this Funding Opportunity Announcement (FOA) is to promote epidemiologic research investigating novel and innovative hypotheses on emerging risk factors (biological, environmental, and social) and their interplay with established risk factors (e.g., viral hepatitis) associated with the development of liver cancer (hepatocellular carcinoma and other histological subtypes) in the United States.
This Funding Opportunity Announcement (FOA) invites grant applications for the Research Specialist Award (R50) in any area of NCI-funded cancer research. This FOA is specifically for laboratory-based scientists.The Research Specialist Award is designed to encourage the development of stable research career opportunities for exceptional scientists who want to continue to pursue research within the context of an existing NCI-funded basic, translational, clinical, or population science cancer research program, but not serve as independent investigators. These non-tenure track scientists, such as researchers within a research program, are vital to sustaining the biomedical research enterprise. It is anticipated that only exceptional scientists who want to pursue research within the context of an existing NCI-funded cancer research program, but not serve as independent investigators, will be competitive for this award.
The purpose of this Funding Opportunity Announcement (FOA) is to support collaborative research projects designed to address adverse sequelae of cancer therapies that persist and become chronic comorbidities or develop as delayed posttreatment effects. This FOA supports basic, translational, and clinical research projects that seek to identify the mechanisms of therapy-induced adverse sequelae, clinically characterize the adverse sequelae, or translate the mechanistic understanding into therapeutic approaches to prevent or minimize the development of long-term sequelae. Research projects should focus on mechanistic studies with translational endpoints and longitudinal clinical phenotyping to identify and validate clinical endpoints (biomarkers, imaging, patient-reported outcomes, or combined elements) for future use in clinical trials that will evaluate the efficacy of interventions designed to prevent or reduce specific adverse sequelae.